Abrams' Clinical Drug Therapy
Rationales for Nursing Practice
13th Edition
• Author(s)Geralyn Frandsen;
Sandra Pennington
TEST BANK
,Question 1
A nurse is preparing to administer a medication that has a
narrow therapeutic index. Which nursing action is the highest
priority to promote safe medication therapy?
A. Administer the medication with food regardless of the
prescription.
B. Verify the prescribed dose, review recent laboratory results if
indicated, and confirm the patient's identity before
administration.
C. Delay administration until the patient requests the
medication.
D. Instruct the patient to stop taking the medication if mild
adverse effects occur.
Correct Answer: B
Rationale:
Medications with a narrow therapeutic index require careful
assessment because small changes in drug concentration can
lead to toxicity or loss of therapeutic effect. Verifying the
correct patient, dose, and relevant laboratory values before
administration helps prevent medication errors and promotes
safe, effective therapy. Automatically administering medications
with food may alter absorption, delaying doses unnecessarily
,can reduce effectiveness, and abruptly stopping medications
without provider guidance may be harmful.
Question 2
A patient asks why the same medication dose affects people
differently. Which response by the nurse is most appropriate?
A. "Every patient absorbs and responds to medications
differently because of factors such as age, organ function,
genetics, and other medications."
B. "Medication doses work exactly the same for everyone."
C. "Differences occur only because some people forget to take
their medications."
D. "Your body will eventually respond exactly like everyone
else's."
Correct Answer: A
Rationale:
Drug response varies among individuals because of physiologic,
genetic, environmental, and pharmacokinetic factors. Age, liver
and kidney function, concurrent medications, and genetic
differences can significantly influence medication effectiveness
and safety. The other responses are inaccurate because they
oversimplify factors influencing drug response.
Question 3
, Before administering a newly prescribed medication, which
assessment should the nurse perform first?
A. Determine the patient's preferred meal schedule.
B. Review the patient's allergy history and verify the medication
order.
C. Ask whether the patient prefers tablets or capsules.
D. Determine whether family members are present.
Correct Answer: B
Rationale:
Reviewing allergies and verifying the medication order are
essential safety steps before administering any medication.
Identifying allergies helps prevent serious hypersensitivity
reactions, while verifying the order reduces medication errors.
Meal preferences and visitor presence are secondary
considerations.
Question 4
A patient reports developing a widespread rash shortly after
taking a newly prescribed medication. What is the nurse's
priority action?
A. Administer the next dose as scheduled.
B. Document the rash and continue therapy.
C. Hold the medication and promptly notify the healthcare
Rationales for Nursing Practice
13th Edition
• Author(s)Geralyn Frandsen;
Sandra Pennington
TEST BANK
,Question 1
A nurse is preparing to administer a medication that has a
narrow therapeutic index. Which nursing action is the highest
priority to promote safe medication therapy?
A. Administer the medication with food regardless of the
prescription.
B. Verify the prescribed dose, review recent laboratory results if
indicated, and confirm the patient's identity before
administration.
C. Delay administration until the patient requests the
medication.
D. Instruct the patient to stop taking the medication if mild
adverse effects occur.
Correct Answer: B
Rationale:
Medications with a narrow therapeutic index require careful
assessment because small changes in drug concentration can
lead to toxicity or loss of therapeutic effect. Verifying the
correct patient, dose, and relevant laboratory values before
administration helps prevent medication errors and promotes
safe, effective therapy. Automatically administering medications
with food may alter absorption, delaying doses unnecessarily
,can reduce effectiveness, and abruptly stopping medications
without provider guidance may be harmful.
Question 2
A patient asks why the same medication dose affects people
differently. Which response by the nurse is most appropriate?
A. "Every patient absorbs and responds to medications
differently because of factors such as age, organ function,
genetics, and other medications."
B. "Medication doses work exactly the same for everyone."
C. "Differences occur only because some people forget to take
their medications."
D. "Your body will eventually respond exactly like everyone
else's."
Correct Answer: A
Rationale:
Drug response varies among individuals because of physiologic,
genetic, environmental, and pharmacokinetic factors. Age, liver
and kidney function, concurrent medications, and genetic
differences can significantly influence medication effectiveness
and safety. The other responses are inaccurate because they
oversimplify factors influencing drug response.
Question 3
, Before administering a newly prescribed medication, which
assessment should the nurse perform first?
A. Determine the patient's preferred meal schedule.
B. Review the patient's allergy history and verify the medication
order.
C. Ask whether the patient prefers tablets or capsules.
D. Determine whether family members are present.
Correct Answer: B
Rationale:
Reviewing allergies and verifying the medication order are
essential safety steps before administering any medication.
Identifying allergies helps prevent serious hypersensitivity
reactions, while verifying the order reduces medication errors.
Meal preferences and visitor presence are secondary
considerations.
Question 4
A patient reports developing a widespread rash shortly after
taking a newly prescribed medication. What is the nurse's
priority action?
A. Administer the next dose as scheduled.
B. Document the rash and continue therapy.
C. Hold the medication and promptly notify the healthcare
