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MODERN BLOOD L
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BANKING &
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TRANSFUSION
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PRACTICES 6TH
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EDITIONDENISEM.
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HARMENING
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,TEST BANK FOR MODERNBLOODBANKING
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& TRANSFUSION PRACTICES
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6TH EDITION L
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DENISE M. HARMENING L
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, Chapter 1 RBCs and Platelet Preservation: Historical Perspectives and Current Trends
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Multiple Choice L
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Identify the choice that best completes the statement or answers the question.
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1. Which metabolic pathway is responsible for generating 90% of the ATP for the RBC?
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a. Pentose phosphate shunt c. Glycolysis L
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b. Luebering-Rapoport shunt d. Methemoglobin reductase L
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2. A unit of blood was returned to the blood bank before it was spiked. Apparently the patient’s IV failed. The
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unit of blood was outside the blood bank for 35 minutes. Which of the statements below is most
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accurate?FT L
a. The unit of blood should be discarded immediately. L
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b. The unit of blood can be returned to inventory. L
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c. The unit of blood must be transfused within 4 hours or be discarded at the end of that time.
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d. The unit of blood must be transfused with 24 hours. L
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3. What is the average diameter of a platelet? FT L L
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a. 5 to 10 µm FT L FT L FT L c. 1 to 2 µm FT L FT L FT L
b. 2 to 4 µm FT L FT L FT L d. 4 to 6 µm F T L F T L FT L FT L FT L
4. In the normal hemoglobin-oxygen dissociation curve, what percentage of oxygen is released to the tissues
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when PO2 averages 40 mm Hg?
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a. 75% c. 100%
b. 25% d. 50% F T L F T L
5. What factors are known to influence platelet metabolism and function?
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a. Storage temperature c. Platelet count L
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b. Initial pH d. All of the above FT L F T L F T L L
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6. Which of the following red blood cell morphologies may be present on the peripheral blood smear as a result
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of loss of RBC membrane?
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a. Spherocytes c. Burr cells L
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b. Target cells d. Schistocytes L
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7. What does the term autologous transfusion refer to?
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a. A parent donating blood for his or her child L
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b. An individual donating blood for a friend L
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c. An individual donating blood for a relative FT L FT L FT L FT L FT L L
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d. An individual donating blood for his or her own transfusion FT L FT L FT L FT L L
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8. What is the primary function of hemoglobin? FT L L
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a. Iron metabolism c. Oxygen transport L
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b. Porphyrin synthesis d. Signal transduction L
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9. All of the following areas of red blood cell biology are crucial for normal erythrocyte survival except:
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a. Cellular metabolism. c. Site of the ABO antigen attachment. L
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b. RBC membrane. d. Hemoglobin structure. FT L F T L F T L L
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, F T L 10. F T L What is the correct biochemical composition of the RBC membrane?
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a. 52% protein, 40% lipid, 8% carbohydrate FT L L
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b. 40% protein, 8% lipid, 52% carbohydrate FT L L
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c. 8% protein, 52% lipid, 40% carbohydrate
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d. 8% lipid, 40% carbohydrate, 52% protein
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F T L 11. F T L F T L All of the following biochemical changes are associated with loss of red blood cell viability upon
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except:
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b. Loss of red blood cell function. L
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a. ACD c. AS-1
b. CPDA-1 d. CPD F T L F T L
F T L 13. The RBC membrane is relatively permeable to all of the following except:
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a. Chloride. c. Bicarbonate.
b. Sodium. d. Water. F T L F T L
F T L 14. What percentage of platelets is sequestered in the spleen as functional reserve after being released
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from the bone marrow?
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a. 30% c. 10%
b. 50% d. 25% F T L F T L
F T L 15. What is the major biochemical consideration in platelet storage?
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a. Glucose metabolism c. Production of carbon dioxide FT L FT L L
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b. Oxygen supply d. Regulation of pH L
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F T L 16. What would the hemoglobin-oxygen dissociation curve depict in a patient exhibiting clinical
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signs of alkalosis?
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b. Shift to the left d. None of the above L
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a. Phospholipid c. Glycolipid
b. Sphingomyelin d. Glycophorin A F T L F T L L
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a. Charles Drew c. Loutit and Mollison L
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b. Karl Landsteiner d. Edward Lindeman FT L F T L F T L L
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F T L 19. A standing order of platelets was shipped to your facility by your supplier. It was inadvertently left
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in the corner of the department until discovered 36 hours later. What would the appropriate action be for the
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blood banker?
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a. If the temperature in the box was 22 +/- 2°C and the platelet swirl seemed OK, it would be
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OK to accept the unit into inventory.
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b. The platelets have fallen outside the supplier’s quality assurance. The unit should be
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discarded because the pH has probably dropped too low and platelet activation has been L
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compromised. L
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c. If the temperature was 1°C to 6°C and the platelet swirl seemed OK, it would be OK to
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