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TEST BANK FOR MODERN BLOOD BANKING &
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TRANSFUSION PRACTICES 7TH EDITION BY
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DENISE M HARMENING
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9780803668881 CHAPTER 1-29 COMPLETE L
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,https://www.stuvia.com/
Chapter 1 RBCs and Platelet Preservation: Historical Perspectives and Current Trends
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Multiple Choice L
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Identify the choice that best completes the statement or answers the question.
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1. Which metabolic pathway is responsible for generating 90% of the ATP for the RBC?L
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a. Pentose phosphate shunt c. Glycolysis L
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b. Luebering-Rapoport shunt d. Methemoglobin reductase L
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2. A unit of blood was returned to the blood bank before it was spiked. Apparently the patient’s IV failed. The
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unit of blood was outside the blood bank for 35 minutes. Which of the statements below is most
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accurate? F,T. L
a. The unit of blood should be discarded immediately. L
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b. The unit of blood can be returned to inventory. F,T. L L
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c. The unit of blood must be transfused within 4 hours or be discarded at the end of that time. L
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d. The unit of blood must be transfused with 24 hours. F,T. L F,T. L F,T. L L
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3. What is the average diameter of a platelet? F,T. L L
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a. 5 to 10 µm F,T. L F,T. L L
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b. 2 to 4 µm F,T. L F,T. L F,T. L d. 4 to 6 µm F , T . L F , T . L F,T. L F,T. L L
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4. In the normal hemoglobin-oxygen dissociation curve, what percentage of oxygen is released to the tissues
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when PO2 averages 40 mm Hg?
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a. 75% c. 100%
b. 25% d. 50% F , T . L
5. What factors are known to influence platelet metabolism and function?
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a. Storage temperature c. Platelet count F,T.L L
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b. Initial pH d. All of the above L
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6. Which of the following red blood cell morphologies may be present on the peripheral blood smear as a
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result of loss of RBC membrane?
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a. Spherocytes c. Burr cells L
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b. Target cells d. Schistocytes L
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7. What does the term autologous transfusion refer to? L
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a. A parent donating blood for his or her child L
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b. An individual donating blood for a friend L
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c. An individual donating blood for a relative L
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d. An individual donating blood for his or her own transfusion L
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8. What is the primary function of hemoglobin? F,T. L L
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9. All of the following areas of red blood cell biology are crucial for normal erythrocyte survival except:
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a. Cellular metabolism. c. Site of the ABO antigen attachment. L
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b. RBC membrane. d. Hemoglobin structure. L
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F , T . L 10. F , T . What is the correct biochemical composition of the RBC membrane?
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a. 52% protein, 40% lipid, 8% carbohydrate L
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b. 40% protein, 8% lipid, 52% carbohydrate L
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c. 8% protein, 52% lipid, 40% carbohydrate F,T. L L
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d. 8% lipid, 40% carbohydrate, 52% protein L
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F , T . L 11. All of the following biochemical changes are associated with loss of red blood cell viability upon storage
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except:
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F , T . L 12. Which red blood cell preservative has a storage time of 35 days?
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a. ACD c. AS-1
b. CPDA-1 d. CPD F , T . L F , T . L
F , T . L 13. The RBC membrane is relatively permeable to all of the following except:
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a. Chloride. c. Bicarbonate.
b. Sodium. d. Water. F , T . L
F , T . L 14. What percentage of platelets is sequestered in the spleen as functional reserve after being released from
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the bone marrow?
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a. 30% c. 10%
b. 50% d. 25% F , T . L F , T . L
F , T . L 15. What is the major biochemical consideration in platelet storage?
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a. Glucose metabolism c. Production of carbon dioxide L
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b. Oxygen supply d. Regulation of pH L
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F , T . L 16. What would the hemoglobin-oxygen dissociation curve depict in a patient exhibiting clinical signs
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of alkalosis?
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a. Normal c. Shift to the right L
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b. Shift to the left d. None of the above L
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F , T . L 17. Name the main lipid components of a red blood cell membrane.
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a. Phospholipid c. Glycolipid
b. Sphingomyelin d. Glycophorin A F , T . L L
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a. Charles Drew c. Loutit and Mollison F,T. L F,T. L F,T.L
b. Karl Landsteiner d. Edward Lindeman F,T.L F , T . L L
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F , T . L 19. A standing order of platelets was shipped to your facility by your supplier. It was inadvertently left in
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the corner of the department until discovered 36 hours later. What would the appropriate action be for the
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blood banker?
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a. If the temperature in the box was 22 +/- 2°C and the platelet swirl seemed OK, it would be F,T. L F,T. L F,T. L L
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OK to accept the unit into inventory. F,T. L F,T . L F,T. L F,T. L F,T. L F,T. L F,T. L
b. The platelets have fallen outside the supplier’s quality assurance. The unit should be F,T. L F,T. L F,T. L F,T. L F,T. L F,T. L F,T. L F,T. L F,T. L F,T. L F,T. L F,T. L
discarded because the pH has probably dropped too low and platelet activation has been
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compromised. F,T. L
c. If the temperature was 1°C to 6°C and the platelet swirl seemed OK, it would be OK to L
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This study source was downloaded by 100000826342158 from CourseHero.com on 09-15-2021 17:54:15 GMT -05:00
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accept the unit into inventory. L
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d. If the platelets appeared OK and passed the platelet swirl test after being placed on the L
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agitator, they could be accepted into the inventory. F,T. L F,T. L F,T. L F,T. L F,T. L F,T. L F,T. L F,T. L
F , T . L 20. Which metabolic pathway permits the accumulation of 2,3 diphosphoglycerate (2,3-DPG)?
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a. Glycolysis c. Pentose phosphate shunt L
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b. Luebering-Rapoport shunt d. Methemoglobin reductase L
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F , T . L 21. F All of the following are consistent with a "shift to the right" of the hemoglobin-oxygen dissociation curve
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except:
a. Increased 2,3-DPG. L
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b. 50% O2 saturation to tissues. L
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c. Decreased 2,3-DPG. L
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d. Decreased hemoglobin affinity for O2. L
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F , T . L 22. What is the normal platelet count range per cubic millimeter?
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a. 100 to 350 c. 50,000 to 200,000 F,T. L F,T. L F,T.L F,T. L
b. 150,000 to 350,000 d. 350,000 to 500,000 L
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F , T . L 23. What cryoprotective agent is added to red blood cells upon freezing?
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a. Dextrose c. Glycerol
b. Adsol d. All of the above F , T . L F,T. L L
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F , T . L 24. If platelets are to be stored for 5 days on a rotator, what is the optimal storage temperature?
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a. 1°C to 6°C c. 35°C to 37°C F,T. L L
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b. 20°C to 24°C d. 1°C to 10°C L
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F , T . L 25. F , T What role do platelets play in hemostasis?
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a. Maintenance of vascular integrity F,T. L F,T.L L
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b. Initial arrest of bleeding by platelet plug formation L
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c. Stabilization of the hemostatic plug L
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d. All of the above L
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F , T . L 26. F , T Which of the following best describes "integral" membrane proteins?
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b. Span the entire membrane surface L
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c. Form the red blood cell cytoskeleton L
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d. None of the above F,T. L F,T. L F,T. L
F , T . L 27. F , T How is stroma-free hemoglobin solution prepared?
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a. Outdated red blood cells are concentrated, and stroma is removed. L
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b. Outdated red blood cells are diluted with saline, and stroma is removed. L
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c. Outdated red blood cells are lysed, and stroma is removed. L
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d. None of the above F,T. L F,T. L F,T. L
F , T . L 28. What is the normal life span of an RBC?
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a. 100 days c. 120 hours F,T. L F,T. L
b. 120 days d. 2 days L
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F , T . L 29. Regarding loss of RBC membrane deformability, all of the following are true except:
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a. Increase in ATP level. F,T. L L
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b. Decrease in ATP level. L
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F.
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TEST BANK FOR MODERN BLOOD BANKING &
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TRANSFUSION PRACTICES 7TH EDITION BY
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DENISE M HARMENING
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9780803668881 CHAPTER 1-29 COMPLETE L
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GUIDE L
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,https://www.stuvia.com/
Chapter 1 RBCs and Platelet Preservation: Historical Perspectives and Current Trends
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Multiple Choice L
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Identify the choice that best completes the statement or answers the question.
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1. Which metabolic pathway is responsible for generating 90% of the ATP for the RBC?L
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a. Pentose phosphate shunt c. Glycolysis L
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b. Luebering-Rapoport shunt d. Methemoglobin reductase L
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2. A unit of blood was returned to the blood bank before it was spiked. Apparently the patient’s IV failed. The
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unit of blood was outside the blood bank for 35 minutes. Which of the statements below is most
F,T. L F,T. L F,T. L F,T. L F,T. L F,T. L F,T. L L
F,T. L
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F,T. F,T.L L
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accurate? F,T. L
a. The unit of blood should be discarded immediately. L
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F,T. F,T. L L
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b. The unit of blood can be returned to inventory. F,T. L L
F,T. F,T. L F,T.L L
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c. The unit of blood must be transfused within 4 hours or be discarded at the end of that time. L
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F. F,T. L F,T. L F,T. L F,T. L L
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d. The unit of blood must be transfused with 24 hours. F,T. L F,T. L F,T. L L
F,T. F,T. L F,T. L F,T. L L
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3. What is the average diameter of a platelet? F,T. L L
F,T. F,T. L F,T.L F,T. L L
F,T. L
F,T.
a. 5 to 10 µm F,T. L F,T. L L
F,T. c. 1 to 2 µm F,T. L F,T. L F,T. L
b. 2 to 4 µm F,T. L F,T. L F,T. L d. 4 to 6 µm F , T . L F , T . L F,T. L F,T. L L
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4. In the normal hemoglobin-oxygen dissociation curve, what percentage of oxygen is released to the tissues
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when PO2 averages 40 mm Hg?
F,T. L F,T. L F , T . L F,T. L F,T. L F,T. L
a. 75% c. 100%
b. 25% d. 50% F , T . L
5. What factors are known to influence platelet metabolism and function?
L
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F,T. F,T.L L
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a. Storage temperature c. Platelet count F,T.L L
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b. Initial pH d. All of the above L
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6. Which of the following red blood cell morphologies may be present on the peripheral blood smear as a
F,T. L L
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F,T. F,T.L F,T. L F,T.L L
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F,T. F,T. L L
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result of loss of RBC membrane?
F,T. L F,T. L F,T. L F,T. L F,T. L F,T. L
a. Spherocytes c. Burr cells L
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b. Target cells d. Schistocytes L
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7. What does the term autologous transfusion refer to? L
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F,T. F,T. L L
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a. A parent donating blood for his or her child L
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F,T. F,T. L F,T. L L
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b. An individual donating blood for a friend L
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c. An individual donating blood for a relative L
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d. An individual donating blood for his or her own transfusion L
F,T. F,T. L F,T. L F,T. L F,T. L F,T. L F,T. L F,T. L F,T.L
8. What is the primary function of hemoglobin? F,T. L L
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F,T. F,T.L F,T. L
a. Iron metabolism F,T.L c. Oxygen transport L
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b. Porphyrin synthesis L
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9. All of the following areas of red blood cell biology are crucial for normal erythrocyte survival except:
L
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a. Cellular metabolism. c. Site of the ABO antigen attachment. L
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b. RBC membrane. d. Hemoglobin structure. L
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This study source was downloaded by 100000826342158 from CourseHero.com on 09-15-2021 17:54:15 GMT -05:00
L
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F , T . L 10. F , T . What is the correct biochemical composition of the RBC membrane?
L F,T. L F,T. L F,T. L F,T. L F,T. L L
F,T. F,T. L F,T. L F,T. L
a. 52% protein, 40% lipid, 8% carbohydrate L
F,T. F,T.L L
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F,T. F,T. L
b. 40% protein, 8% lipid, 52% carbohydrate L
F,T. F,T. L L
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c. 8% protein, 52% lipid, 40% carbohydrate F,T. L L
F,T. F,T. L F,T.L F,T. L
d. 8% lipid, 40% carbohydrate, 52% protein L
F,T. F,T.L L
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F , T . L 11. All of the following biochemical changes are associated with loss of red blood cell viability upon storage
F , T . L L
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except:
a. Decreased pH. c. Increased ATP level. F,T. L L
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b. Loss of red blood cell function. d. Decreased glucose consumption. F,T.L F,T. L F,T. L L
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F , T . L 12. Which red blood cell preservative has a storage time of 35 days?
F , T . L L
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F,T. F,T. L F,T. L F,T. L F,T. L F,T. L L
F,T. F,T. L F,T. L F,T. L
a. ACD c. AS-1
b. CPDA-1 d. CPD F , T . L F , T . L
F , T . L 13. The RBC membrane is relatively permeable to all of the following except:
F , T . L F,T. L F,T. L F,T. L F,T. L F,T.L F,T. L F,T. L F,T. L F,T. L L
F,T. F,T. L
a. Chloride. c. Bicarbonate.
b. Sodium. d. Water. F , T . L
F , T . L 14. What percentage of platelets is sequestered in the spleen as functional reserve after being released from
F,T. L F,T. L F,T.L F,T. L F,T. L L
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F,T. F,T. L F,T. L F,T. L F,T. L F,T. L L
F,T.
the bone marrow?
L
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a. 30% c. 10%
b. 50% d. 25% F , T . L F , T . L
F , T . L 15. What is the major biochemical consideration in platelet storage?
F , T . L F,T.L L
F,T. F,T. L F,T. L F,T. L F,T. L F,T.L F,T. L
a. Glucose metabolism c. Production of carbon dioxide L
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F,T. L
F,T. L
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b. Oxygen supply d. Regulation of pH L
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F , T . L 16. What would the hemoglobin-oxygen dissociation curve depict in a patient exhibiting clinical signs
F,T. L F,T. L F,T. L F,T. L L
F,T. F,T.L F,T. L F,T. L L
F,T. F,T. L L
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F,T. F,T. L
of alkalosis?
F,T. L F,T. L
a. Normal c. Shift to the right L
F,T. F,T. L F,T. L
b. Shift to the left d. None of the above L
F,T. F,T. L F,T. L F , T . L F,T. L L
F,T. F,T . L
F , T . L 17. Name the main lipid components of a red blood cell membrane.
F , T . L F,T. L F,T. L F,T. L L
F,T. F,T. L F,T. L L
F,T. F,T. L F,T. L F,T. L
a. Phospholipid c. Glycolipid
b. Sphingomyelin d. Glycophorin A F , T . L L
.,T
F
F , T . L 18. The ABO blood groups were discovered in 1901 by whom?
F , T . L L
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F F,T. L F,T. L F,T. L F,T. L F,T. L F,T. L L
F,T. L
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a. Charles Drew c. Loutit and Mollison F,T. L F,T. L F,T.L
b. Karl Landsteiner d. Edward Lindeman F,T.L F , T . L L
F,T.
F , T . L 19. A standing order of platelets was shipped to your facility by your supplier. It was inadvertently left in
F,T. L F,T. L F,T. L F,T. L F,T. L F,T. L F,T. L F,T. L F,T. L F,T. L F,T. L F,T. L F,T. L F,T. L F,T. L F,T. L F,T. L F,T. L
the corner of the department until discovered 36 hours later. What would the appropriate action be for the
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F,T. L
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blood banker?
F,T. L F,T. L
a. If the temperature in the box was 22 +/- 2°C and the platelet swirl seemed OK, it would be F,T. L F,T. L F,T. L L
F,T. L
F,T. L
F,T. F,T. L F,T. L L
,FT. L
F,T. F,T.L L
F,T. F,T. L L
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F,T. L
F,T. L
F,T. L
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OK to accept the unit into inventory. F,T. L F,T . L F,T. L F,T. L F,T. L F,T. L F,T. L
b. The platelets have fallen outside the supplier’s quality assurance. The unit should be F,T. L F,T. L F,T. L F,T. L F,T. L F,T. L F,T. L F,T. L F,T. L F,T. L F,T. L F,T. L
discarded because the pH has probably dropped too low and platelet activation has been
F,T. L L
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F,T. L
,FT. L
F,T. L
F,T. F,T.L F,T. L L
F,T. L
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compromised. F,T. L
c. If the temperature was 1°C to 6°C and the platelet swirl seemed OK, it would be OK to L
F,T. L
F,T. L
F,T. F,T. L L
F,T. L
F,T. L
F,T. L
F,T. L
F,T. F,T. L F,T. L L
F,T. L
F,T. F,T.L L
F,T. L
F,T. L
F,T.
This study source was downloaded by 100000826342158 from CourseHero.com on 09-15-2021 17:54:15 GMT -05:00
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F. L
F,T. L
F,T. F,T.L L
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accept the unit into inventory. L
F,T. L
F,T. F,T.L L
F,T.
d. If the platelets appeared OK and passed the platelet swirl test after being placed on the L
F,T. F,T. L F,T. L F,T. L L
F,T. L
F,T. F,T.L L
F,T. F,T. L L
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agitator, they could be accepted into the inventory. F,T. L F,T. L F,T. L F,T. L F,T. L F,T. L F,T. L F,T. L
F , T . L 20. Which metabolic pathway permits the accumulation of 2,3 diphosphoglycerate (2,3-DPG)?
F , T . L L
F,T. F,T.L L
,T
F. F,T.L F,T. L F,T.L F,T. L F,T.L L
F,T.
a. Glycolysis c. Pentose phosphate shunt L
F,T. L
F,T.
b. Luebering-Rapoport shunt d. Methemoglobin reductase L
,T
F. F , T . L L
F,T.
F , T . L 21. F All of the following are consistent with a "shift to the right" of the hemoglobin-oxygen dissociation curve
, T . L F,T. L F,T. L L
F,T. L
F,T. L
F,T. F,T. L L
F,T. L
F,T. F,T. L L
F,T. F,T. L F,T. L L
F,T. F,T.L L
F,T. L
F,T.
except:
a. Increased 2,3-DPG. L
.,T
F
b. 50% O2 saturation to tissues. L
F,T.
F , T . L L
F,T. L
F,T.
c. Decreased 2,3-DPG. L
.,T
F
d. Decreased hemoglobin affinity for O2. L
.,T
F L
,T
F. L
.,T
F L
,T
F.
F , T . L 22. What is the normal platelet count range per cubic millimeter?
F , T . L F,T. L F,T. L F,T. L F,T. L F,T. L L
F,T. F,T. L F,T. L F,T.L
a. 100 to 350 c. 50,000 to 200,000 F,T. L F,T. L F,T.L F,T. L
b. 150,000 to 350,000 d. 350,000 to 500,000 L
F,T. F,T. L F , T . L F,T. L F,T. L
F , T . L 23. What cryoprotective agent is added to red blood cells upon freezing?
F , T . L L
F,T. F,T. L F,T. L F,T. L F,T. L F,T. L L
F,T. F,T. L F,T. L F,T. L
a. Dextrose c. Glycerol
b. Adsol d. All of the above F , T . L F,T. L L
F,T. F,T. L
F , T . L 24. If platelets are to be stored for 5 days on a rotator, what is the optimal storage temperature?
F , T . L F,T. L L
F,T. L
F,T. L
F,T. F,T. L L
F,T. F,T. L F,T. L F,T. L L
F,T. L
F,T. F,T. L L
F,T. L
F,T. F,T.L L
F,T. F,T. L
a. 1°C to 6°C c. 35°C to 37°C F,T. L L
F,T. F,T. L F,T. L
b. 20°C to 24°C d. 1°C to 10°C L
F,T. F,T. L F , T . L F,T. L F,T. L
F , T . L 25. F , T What role do platelets play in hemostasis?
. L F,T. L F,T. L F,T. L F,T. L L
F,T. F,T. L
a. Maintenance of vascular integrity F,T. L F,T.L L
F,T.
b. Initial arrest of bleeding by platelet plug formation L
F,T. L
F,T. F,T. L L
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F. L
F,T. L
F,T. L
F,T.
c. Stabilization of the hemostatic plug L
F,T. L
F,T. L
F,T. L
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F.
d. All of the above L
F,T. F,T. L F,T.L
F , T . L 26. F , T Which of the following best describes "integral" membrane proteins?
. L F,T. L L
F,T. L
F,T. L
F,T. F,T. L L
F,T. L
F,T. F,T. L
a. Reside at the cytoplasmic surface of membrane F,T.L F,T. L F,T.L F,T. L L
F,T. L
F,T.
b. Span the entire membrane surface L
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F. L
F,T. L
F,T. F,T. L
c. Form the red blood cell cytoskeleton L
,T
F. F,T. L F,T. L L
F,T. F,T. L
d. None of the above F,T. L F,T. L F,T. L
F , T . L 27. F , T How is stroma-free hemoglobin solution prepared?
. L F,T. L F,T. L F,T. L F,T.L L
F,T.
a. Outdated red blood cells are concentrated, and stroma is removed. L
F,T. L
F,T. F,T. L F,T. L F,T. L L
F,T. L
,FT. F,T.L F,T.L
b. Outdated red blood cells are diluted with saline, and stroma is removed. L
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F. F,T. L L
F,T. L
F,T. L
F,T. L
F,T. L
F,T. L
F,T. F,T.L L
F,T. L
F,T.
c. Outdated red blood cells are lysed, and stroma is removed. L
F,T. L
F,T. L
F,T. L
F,T. L
F,T. L
F,T. L
F,T. F,T. L F,T.L
d. None of the above F,T. L F,T. L F,T. L
F , T . L 28. What is the normal life span of an RBC?
F , T . L F,T.L F,T. L F,T. L F,T. L F,T. L L
F,T. F,T. L F,T. L
a. 100 days c. 120 hours F,T. L F,T. L
b. 120 days d. 2 days L
F,T. F , T . L F,T. L
F , T . L 29. Regarding loss of RBC membrane deformability, all of the following are true except:
F , T . L F,T.L F,T. L F,T. L F,T.L F,T. L F,T. L F,T. L L
F,T. F,T. L L
F,T. F,T. L F,T. L
a. Increase in ATP level. F,T. L L
.,T
F L
.,T
F
b. Decrease in ATP level. L
F,T. L
.,T
F L
,T
F.
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L
,T
F. L
F,T. L
F,T. L
F,T. L
F,T. F,T.L L
F,T. L
F,T. L
F,T. L
F,T. L
F,T. F,T.L L
F,T.
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