NBME CBSE REAL EXAM 200
QUESTIONS AND ANSWERS LATEST
2026-2027 COMPLETE EXAM(graded
A+)
70yo M dies in a motor vehicle collision. Was
undergoing evaluation for occult blood in the stool.
Photo of transverse colon shown. Dx? - ANSWER--
Tubular adenoma or villous polyp. GI blood loss
suggests a risk for malignancy
38yo M truck driver with 1-week hx of watery, itchy
eyes and a runny nose. Physical shows inflamed nasal
mucosa. No congestion in lower lung.
Pharmacotherapy? - ANSWER--Loratadine--> less
sedating antihistamine
16yo girl with 3-day hx of fever, nonproductive cough,
and fatigue. T 38.3, P 88/min, BP 102-70. PE shows pale
conjunctivae. CXR shows bilateral interstitial infiltrates.
Blood spontaenously agglutinates while awaiting
transport to the laboratory. Antibody isotypes causing
agglutination? - ANSWER--IgM (mono and
mycoplasma)
,NBME CBSE REAL EXAM 200
QUESTIONS AND ANSWERS LATEST
2026-2027 COMPLETE EXAM(graded
A+)
24yo M with small tender blisters on his penis 3 days
after unprotected sex. Photograph shown. Causal
agent? - ANSWER--HSV-2
42yo F with 3-year hx of an intermittent facial rash,
including the forehead, eyelids, nose, and cheeks. Rash
seems to be getting worse since she moved from New
York to Florida last year. Spicy foods precipitate a
flushing reaction that seems to exacerbate the rash. PE
shows erythema over the nose and cheeks, with
scattered telangiectasias and a few papules. Dx? -
ANSWER--Rosacea
53yo M returned from Africa, has fever, headache, and
abdominal discomfort. Received appropriate
vaccinations prior to the trip. T 39.4C. A wright-stained
peripheral smear shown (ring forms in RBCs). Dx? -
ANSWER--Malaria
,NBME CBSE REAL EXAM 200
QUESTIONS AND ANSWERS LATEST
2026-2027 COMPLETE EXAM(graded
A+)
68yo F with T2DM and hypertension that has been
poorly controlled despite hydrochlorothiazide
treatment. BP 150/96, Labs show serum glucose
concentration of 130 and proteinuria. In addition to
current Rx, which is most appropriate
pharmacotherapy? - ANSWER--ACE I (Lisinopril)
66yo M with stage IV colon cancer with 3-day hx of
severe diarrhea after receiving chemotherapy with
flourouracil, leucovorin, and irinotecan. Prescribed
opioid antidiarrheal agent with no CNS effects. Which
med? - ANSWER--Loperamide
35yo M in ED with 2-hour hx of sever fatigue and
dizziness. Had profuse, watery diarrhea for 8 hours
despite a lack of oral intake. Recently returned from a
medical relief trip to a remove village in Honduras. T
36.7 C, P 122/min, BP 90/50. PE shows dry skin and
decreased capillary refill. Stool for occult blood is
negative; stool is gray and turbid. Gram stain shows
gram-negative, comma-shaped bacteria; no
, NBME CBSE REAL EXAM 200
QUESTIONS AND ANSWERS LATEST
2026-2027 COMPLETE EXAM(graded
A+)
erythrocytes of leukocytes. MOA of toxin? - ANSWER--
V. Cholerae--> activates AC
59yo F with gradual onset of lack of muscle control in
her left arm and leg. Sx 1 mo ago after dx with
metastatic breast cancer. PE shows ataxia of left upper
and lower extremities. Muscle strength, DTR,
sensation, proprioception normal. Metastatic tumor in
which location? - ANSWER--Cerebellum
Newborn delivered at 38 weeks' gestation weighs 1800
g. PE shows petechial rash, microcephaly, and
hepatosplenomegaly. Serologic test for CMV: IgG + in
mother, + in newborn; IGM - in mother, + in newborn.
Explanation? - ANSWER--Congenital CMV infection
Female newborn is delivered at 38 weeks' gestation.
Apgar 8 and 8 at 1/5 min. PE shows a bulging,
fluod0filled mass approximately 5 cm in diameter in
the midline over the lumbosacral region. No
QUESTIONS AND ANSWERS LATEST
2026-2027 COMPLETE EXAM(graded
A+)
70yo M dies in a motor vehicle collision. Was
undergoing evaluation for occult blood in the stool.
Photo of transverse colon shown. Dx? - ANSWER--
Tubular adenoma or villous polyp. GI blood loss
suggests a risk for malignancy
38yo M truck driver with 1-week hx of watery, itchy
eyes and a runny nose. Physical shows inflamed nasal
mucosa. No congestion in lower lung.
Pharmacotherapy? - ANSWER--Loratadine--> less
sedating antihistamine
16yo girl with 3-day hx of fever, nonproductive cough,
and fatigue. T 38.3, P 88/min, BP 102-70. PE shows pale
conjunctivae. CXR shows bilateral interstitial infiltrates.
Blood spontaenously agglutinates while awaiting
transport to the laboratory. Antibody isotypes causing
agglutination? - ANSWER--IgM (mono and
mycoplasma)
,NBME CBSE REAL EXAM 200
QUESTIONS AND ANSWERS LATEST
2026-2027 COMPLETE EXAM(graded
A+)
24yo M with small tender blisters on his penis 3 days
after unprotected sex. Photograph shown. Causal
agent? - ANSWER--HSV-2
42yo F with 3-year hx of an intermittent facial rash,
including the forehead, eyelids, nose, and cheeks. Rash
seems to be getting worse since she moved from New
York to Florida last year. Spicy foods precipitate a
flushing reaction that seems to exacerbate the rash. PE
shows erythema over the nose and cheeks, with
scattered telangiectasias and a few papules. Dx? -
ANSWER--Rosacea
53yo M returned from Africa, has fever, headache, and
abdominal discomfort. Received appropriate
vaccinations prior to the trip. T 39.4C. A wright-stained
peripheral smear shown (ring forms in RBCs). Dx? -
ANSWER--Malaria
,NBME CBSE REAL EXAM 200
QUESTIONS AND ANSWERS LATEST
2026-2027 COMPLETE EXAM(graded
A+)
68yo F with T2DM and hypertension that has been
poorly controlled despite hydrochlorothiazide
treatment. BP 150/96, Labs show serum glucose
concentration of 130 and proteinuria. In addition to
current Rx, which is most appropriate
pharmacotherapy? - ANSWER--ACE I (Lisinopril)
66yo M with stage IV colon cancer with 3-day hx of
severe diarrhea after receiving chemotherapy with
flourouracil, leucovorin, and irinotecan. Prescribed
opioid antidiarrheal agent with no CNS effects. Which
med? - ANSWER--Loperamide
35yo M in ED with 2-hour hx of sever fatigue and
dizziness. Had profuse, watery diarrhea for 8 hours
despite a lack of oral intake. Recently returned from a
medical relief trip to a remove village in Honduras. T
36.7 C, P 122/min, BP 90/50. PE shows dry skin and
decreased capillary refill. Stool for occult blood is
negative; stool is gray and turbid. Gram stain shows
gram-negative, comma-shaped bacteria; no
, NBME CBSE REAL EXAM 200
QUESTIONS AND ANSWERS LATEST
2026-2027 COMPLETE EXAM(graded
A+)
erythrocytes of leukocytes. MOA of toxin? - ANSWER--
V. Cholerae--> activates AC
59yo F with gradual onset of lack of muscle control in
her left arm and leg. Sx 1 mo ago after dx with
metastatic breast cancer. PE shows ataxia of left upper
and lower extremities. Muscle strength, DTR,
sensation, proprioception normal. Metastatic tumor in
which location? - ANSWER--Cerebellum
Newborn delivered at 38 weeks' gestation weighs 1800
g. PE shows petechial rash, microcephaly, and
hepatosplenomegaly. Serologic test for CMV: IgG + in
mother, + in newborn; IGM - in mother, + in newborn.
Explanation? - ANSWER--Congenital CMV infection
Female newborn is delivered at 38 weeks' gestation.
Apgar 8 and 8 at 1/5 min. PE shows a bulging,
fluod0filled mass approximately 5 cm in diameter in
the midline over the lumbosacral region. No
