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HESI Fundamentals 2026 | 39 Practice Questions with Correct Answers & Detailed Rationales

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This document contains 39 HESI Fundamentals practice questions for 2026, complete with correct answers and detailed rationales. It is designed to help nursing students strengthen core nursing knowledge and improve exam readiness for both HESI and NCLEX assessments. The questions cover essential nursing topics including patient safety, infection control, medication administration, IV therapy, fluid and electrolyte balance, basic nursing procedures, prioritization, delegation, and therapeutic communication. Each question includes a clear and detailed rationale explaining why the correct answer is right and why the other options are incorrect. This resource is ideal for RN and PN nursing students who want a structured, high-quality review tool for mastering nursing fundamentals and improving test performance.

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HESI FUNDAMENTALS 2026 |39 PRACTICE
QUESTIONS, CORRECT ANSWERS&DETAILED
RATIONALES


The healthcare provider prescribes the diuretic metolazone (Zaroxolyn) 7.5
mg PO. Zaroxolyn is available in 5 mg tablets. How much should the nurse
plan to administer?
A. ½ tablet.
B. 1 tablet.
C. 1½ tablets.
D. 2 tablets

Correct Answer: C
The healthcare provider prescribes furosemide (Lasix) 15 mg IV stat. On hand
is Lasix 20 mg/2 ml. How many milliliters should the nurse administer? A. 1
ml.
B. 1.5 ml.
C. 1.75 ml.
D. 2 ml

Correct Answer: B
Heparin 20,000 units in 500 ml D5W at 50 ml/hour has been infusing for 5½
hours. How much heparin has the client received?
A. 11,000 units.
B. 13,000 units.
C. 15,000 units.
D. 17,000 units

Correct Answer: A
The healthcare provider prescribes morphine sulfate 4mg IM STAT. Morphine
comes in 8 mg per ml. How many ml should the nurse administer?
A. 0.5 ml.
B. 1 ml.

, C. 1.5 ml.
D. 2 ml

Correct Answer: A
The nurse prepares a 1,000 ml IV of 5% dextrose and water to be infused over
8 hours. The infusion set delivers 10 drops per milliliter. The nurse should
regulate the IV to administer approximately how many drops per minute?
A. 80
B. 8
C. 21
D. 25

Correct Answer: C
Which action is most important for the nurse to implement when donning
sterile gloves?
A. Maintain thumb at a ninety degree angle.
B. Hold hands with fingers down while gloving.
C. Keep gloved hands above the elbows.
D. Put the glove on the dominant hand first

Correct Answer: C
A client's infusion of normal saline infiltrated earlier today, and approximately
500 ml of saline infused into the subcutaneous tissue. The client is now
complaining of excruciating arm pain and demanding "stronger pain
medications." What initial action is most important for the nurse to take?
A. Ask about any past history of drug abuse or addiction.
B. Measure the pulse volume and capillary refill distal to the infiltration.
C. Compress the infiltrated tissue to measure the degree of edema.
D. Evaluate the extent of ecchymosis over the forearm area

Correct Answer: B
An elderly male client who is unresponsive following a cerebral vascular
accident (CVA) is receiving bolus enteral feedings though a gastrostomy tube.
What is the best client position for administration of the bolus tube feedings?
A. Prone.
B. Fowler's.
C. Sims'.

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