What were safety considerations (ALL) for Digoxin?
- Check the apical pulse for 1 minute
- Hold med if apical pulse is less than 60
- Therapeutic range for Digoxin: 0.8-2
- Antidote to Digoxin: Digiband/Digoxin Immune Fab
- Digoxin is (+) INO & DROMO but (-) for CHRONO
What were lab values, Antidote, for Heparin? Warfarin?
- Heparin lab value:
- Heparin Antidote: Protamine Sulfate
- Warfarin lab value
- Antidote Warfarin: Vitamin K
What were the adrenergic agonist drugs that were Vessicant risks?
NTG why do you avoid extremes in weather?
- Can cause extreme vasodilation
What drug could cause Lupus (SLE)?
- Procainamide
How do we treat Torsades de Pontes?
- Magnesium sulfate IV P
- Isoproterenol → Adrenergic Agnoist
What are the INO, CHRONO, DROMO for Adrenergic Agonists?
- Inotrope: force of contraction of the heart muscle,
- (+) inotrope: increases force of contraction, increases the heart’s
pumping ability
- ex)Digoxin, Adrenaline
, - (-) inotrope: decreases the force of contractions, decreasing the heart’s
pumping ability
- ex) beta-blockers, calcium channel blockers
- Chronotrope: affects how fast the heart beats, affects the heart rate
- (+) chronotrope: increases the heart rate
- ex) Atropine, epinephrine
- (-) chronotrope: decreases the heart rate
- ex) beta-blockers, calcium channel blockers
- Dromotrope: affects the conduction velocity of electrical impulses through the
heart, particularly the AV node
- (+) dromotrope: increases the speed at which the electrical speed
impulses travel through the heart
- ex) sympathomimetic drugs
- (-) dromotrope: decreases the conduction velocity
- ex) Calcium channel blockers, certain antiarrhythmics
Gente de la Clase: What is Inotropic, Chronotropic, and Dromotropic effect of
medications?
Which drug is a + (pos) Inotrope, - (neg) Chronotrope?
- Digoxin
Which drugs were all + Ino, Chrono, Dromo?
- Adrenergic Agonists
- Epinephrine
- Norepinephrine
- Dopamine
- Isoperenolol
Which were all - Ino, Chrono, Dromo?
- Calcium Channel Blcokers that end with pine (think Chris Pine for Calcium
Channel )
What drug class was a notorious Extravasation risk?
- Adrenergic Agonist
- Check the apical pulse for 1 minute
- Hold med if apical pulse is less than 60
- Therapeutic range for Digoxin: 0.8-2
- Antidote to Digoxin: Digiband/Digoxin Immune Fab
- Digoxin is (+) INO & DROMO but (-) for CHRONO
What were lab values, Antidote, for Heparin? Warfarin?
- Heparin lab value:
- Heparin Antidote: Protamine Sulfate
- Warfarin lab value
- Antidote Warfarin: Vitamin K
What were the adrenergic agonist drugs that were Vessicant risks?
NTG why do you avoid extremes in weather?
- Can cause extreme vasodilation
What drug could cause Lupus (SLE)?
- Procainamide
How do we treat Torsades de Pontes?
- Magnesium sulfate IV P
- Isoproterenol → Adrenergic Agnoist
What are the INO, CHRONO, DROMO for Adrenergic Agonists?
- Inotrope: force of contraction of the heart muscle,
- (+) inotrope: increases force of contraction, increases the heart’s
pumping ability
- ex)Digoxin, Adrenaline
, - (-) inotrope: decreases the force of contractions, decreasing the heart’s
pumping ability
- ex) beta-blockers, calcium channel blockers
- Chronotrope: affects how fast the heart beats, affects the heart rate
- (+) chronotrope: increases the heart rate
- ex) Atropine, epinephrine
- (-) chronotrope: decreases the heart rate
- ex) beta-blockers, calcium channel blockers
- Dromotrope: affects the conduction velocity of electrical impulses through the
heart, particularly the AV node
- (+) dromotrope: increases the speed at which the electrical speed
impulses travel through the heart
- ex) sympathomimetic drugs
- (-) dromotrope: decreases the conduction velocity
- ex) Calcium channel blockers, certain antiarrhythmics
Gente de la Clase: What is Inotropic, Chronotropic, and Dromotropic effect of
medications?
Which drug is a + (pos) Inotrope, - (neg) Chronotrope?
- Digoxin
Which drugs were all + Ino, Chrono, Dromo?
- Adrenergic Agonists
- Epinephrine
- Norepinephrine
- Dopamine
- Isoperenolol
Which were all - Ino, Chrono, Dromo?
- Calcium Channel Blcokers that end with pine (think Chris Pine for Calcium
Channel )
What drug class was a notorious Extravasation risk?
- Adrenergic Agonist
