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Coagulation Flashcards _ Quizlet (1).pdf

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Coagulation Flashcards _ Quizlet (1).pdf

Institution
Clinical Chemistry
Course
Clinical chemistry

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Science Medicine Hematology


Coagulation
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Chemistry (ASCP MLT BOARD EXAM... Hematology Practice questions Hematology (MLS ASCP) Hemato

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Anticoagulant drugs that are direct thrombin inhibitors PT, aPTT, Escarin clotting time
(ex: argatroban & bivalirudin) can prolong what clot-
based assays?


Escarin Clotting time a laboratory test that measures how long it takes for blood to clot after the
addition of a protein called ecarin. Ecarin, derived from the venom of the saw-
scaled viper, activates a protein called prothrombin to form meizothrombin, which
then leads to clotting. -used to monitor the effects of direct thrombin inhibitors
(DTIs)


In patients who developed heparin-induced Direct thrombin inhibitors
thrombocytopenia with thrombosis (HIT), what can/ be Ex: Argatroban * Bivalirudin (can be substituted for unfractionated heparin in
used to prevent ischemic stroke patients with HIT)

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