T L 12263423
TEST BANK FOR ADVANCED ASSESSMENT: T L T L T L T L T L
T L INTERPRETING FINDINGS AND FORMULATING T L T L T L T L
DIFFERENTIAL DIAGNOSES 4th Edition, Mary Jo T L L
T L
T L
T L
T L
T
Goolsby, Laurie Grubbs-A+ GRADES-2023-2024
T L T L T L T L
Chapter 1: Clinical reasoning, differential diagnosis, evidence-based practice, and symptom ana
L
T L
T L
T L
T L
T L
T L
T L
T L
T L
T
Multiple Choice T L
Identify the choice that best completes the statement or answers the question.
L
T L
T L
T L
T L
T L
T L
T L
T L
T L
T L
T
1. Which type of clinical decision-making is most reliable? L
T L
T L
T L
T L
T L
T L
T
A. Intuitive
B. Analytical
C. Experiential
D. Augenblick
2. Which of the following is false? To obtain adequate history, health-care providers must be:
L
T L
T L
T L
T L
T L
T T L L
T L
T L
T T L L
T L
T
A. Methodical and systematic L
T L
T
B. Attentive to the patient’s verbal and nonverbal language L
T L
T L
T L
T T L L
T L
T
C. Able to accurately interpret the patient’s responses
L
T L
T L
T L
T L
T L
T
D. Adept at reading into the patient’s statements
L
T L
T L
T L
T L
T L
T
3. Essential parts of a health history include all of the following except: L
T L
T L
T T L L
T L
T L
T L
T L
T L
T T L
A. Chief complaint L
T
B. History of the present illness L
T L
T L
T L
T
C. Current vital signs L
T L
T
D. All of the above are essential history components
L
T L
T L
T T L L
T L
T L
T
4. Which of the following is false? While performing the physical examination, the examiner must be able to:
L
T L
T T L L
T T L L
T L
T L
T L
T L
T L
T L
T L
T L
T L
T L
T
A. Differentiate between normal and abnormal findings L
T L
T L
T L
T L
T
B. Recall knowledge of a range of conditions and their associated signs and symptoms
L
T T L L
T L
T L
T T L L
T L
T L
T L
T L
T L
T
C. Recognize how certain conditions affect the response to other conditions L
T L
T T L L
T L
T L
T L
T L
T L
T
D. Foresee unpredictable findings T L T L
5. The following is the least reliable source of information for diagnostic statistics:
L
T L
T L
T L
T L
T L
T L
T L
T L
T L
T L
T
A. Evidence-based investigations L
T
B. Primary reports of research L
T L
T L
T
C. Estimation based on a provider’s experience L
T L
T L
T L
T L
T
D. Published meta-analyses T L
6. The following can be used to assist in sound clinical decision-making:
L
T T L T L L
T L
T L
T L
T L
T L
T T L
A. Algorithm published in a peer-reviewed journal article L
T L
T L
T L
T L
T L
T
B. Clinical practice guidelines L
T L
T
C. Evidence-based research L
T
D. All of the above
L
T L
T L
T
7. If a diagnostic study has high sensitivity, this indicates a:
L
T L
T L
T L
T L
T L
T T L L
T L
T
A. High percentage of persons with the given condition will have an abnormal result
L
T L
T L
T L
T L
T L
T L
T L
T L
T L
T L
T L
T
B. Low percentage of persons with the given condition will have an abnormal result
L
T T L L
T T L L
T L
T T L L
T L
T L
T L
T L
T
C. Low likelihood of normal result in persons without a given condition
L
T T L L
T L
T L
T L
T L
T T L L
T L
T
D. None of the above L
T L
T L
T
8. If a diagnostic study has high specificity, this indicates a:
L
T L
T L
T L
T T L L
T T L L
T L
T
A. Low percentage of healthy individuals will show a normal result
L
T L
T T L L
T L
T L
T T L L
T T L
B. High percentage of healthy individuals will show a normal result
L
T L
T L
T L
T L
T L
T L
T L
T T L
C. High percentage of individuals with a disorder will show a normal result
T L L
T L
T T L T L L
T L
T L
T L
T L
T L
T
D. Low percentage of individuals with a disorder will show an abnormal result
L
T T L L
T L
T L
T L
T L
T T L L
T L
T L
T
9. A likelihood ratio above 1 indicates that a diagnostic test showing a:
L
T L
T L
T T L L
T L
T L
T L
T L
T L
T L
T
A. Positive result is strongly associated with the disease T L L
T L
T L
T L
T L
T L
T
B. Negative result is strongly associated with absence of the disease
L
T L
T T L L
T L
T L
T T L L
T L
T
C. Positive result is weakly associated with the disease T L L
T T L L
T L
T L
T L
T
D. Negative result is weakly associated with absence of the disease L
T L
T L
T L
T T L L
T L
T L
T L
T
Downloaded by Anna Maina () L
T L
T L
T L
T
, lOMoAR T L cPSD|
10. Which of the following clinical reasoning tools is defined as evidence-based resource based on mathematical modeling L
T L
T L
T L
T L
T L
T L
T L
T
T L 12263423
L
T L
T L
T L
T L
T L
T L
T
to express the likelihood of a condition in select situations, settings, and/or patients?
T L T L L
T L
T T L T L T L L
T T L T L T L T L L
T
A. Clinical practice guideline L
T L
T
B. Clinical decision rule L
T T L
C. Clinical algorithm L
T
Chapter 1: Clinical reasoning, differential diagnosis, evidence-based practice, and symptom ana
L
T L
T L
T L
T L
T L
T L
T L
T L
T L
T
Answer Section
L
T
MULTIPLE CHOICE L
T
1. ANS: B
Croskerry (2009) describes two major types of clinical diagnostic decision-making: intuitive and analytical. Intuitive
L
T T L T L T L L
T T L T L L
T L
T T L T L L
T T L
Tdecision-making (similar to Augenblink decision-making) is based on the experience and intuition of the clinician and is less
L T L T L L
T L
T L
T L
T L
T T L L
T L
T T L L
T L
T T L L
T L
T L
T
Treliable and paired with fairly common errors. In contrast, analytical decision-making is based on careful consideration and
L L
T L
T L
T L
T T L T L L
T L
T T L L
T L
T T L L
T T L L
T L
T
Thas greater reliability with rare errors.
L L
T T L T L L
T T L
PTS: 1
2. ANS: D
To obtain adequate history, providers must be well organized, attentive to the patient’s verbal and nonverbal language, and able
T L L
T L
T L
T T L L
T L
T L
T L
T T L T L L
T L
T L
T T L L
T L
T L
T
Tto accurately interpret the patient’s responses to questions. Rather than reading into the patient’s statements, they clarify any
L T L T L L
T L
T L
T T L T L T L L
T L
T L
T T L L
T L
T L
T T L T L
Tareas of uncertainty.
L L
T T L
PTS: 1
3. ANS: C
Vital signs are part of the physical examination portion of patient assessment, not part of the health history.
L
T L
T L
T L
T L
T L
T L
T L
T L
T T L L
T T L L
T T L L
T L
T T L
PTS: 1
4. ANS: D
While performing the physical examination, the examiner must be able to differentiate between normal and abnormal findings,
L
T L
T L
T L
T L
T T L L
T L
T L
T T L T L L
T L
T L
T L
T L
T
Trecall knowledge of a range of conditions, including their associated signs and symptoms, recognize how certain conditions
L T L L
T L
T T L T L L
T T L L
T L
T L
T L
T L
T T L L
T L
T L
T
Taffect the response to other conditions, and distinguish the relevance of varied abnormal findings.
L T L T L L
T T L L
T L
T L
T T L L
T T L T L T L L
T
PTS: 1
5. ANS: C
Sources for diagnostic statistics include textbooks, primary reports of research, and published meta-analyses. Another source
L
T L
T L
T L
T T L L
T T L L
T T L L
T L
T L
T T L L
T
L
Tof statistics, the one that has been most widely used and available for application to the reasoning process, is the estimation based
T L L
T L
T L
T L
T L
T L
T L
T L
T L
T L
T L
T L
T T L T L L
T L
T L
T L
T L
T L
T
on a provider’s experience, although these are rarely accurate. Over the past decade, the availability of evidence on which to
L
T T L T L L
T L
T T L L
T L
T T L L
T L
T T L L
T L
T L
T T L T L L
T T L T L
L
Tbase clinical reasoning is improving, and there is an increasing expectation that clinical reasoning be based on scientific
T L L
T L
T L
T T L T L L
T L
T T L L
T L
T L
T T L L
T L
T L
T L
T
L
Tevidence.
Evidence-based statistics are also increasingly being used to develop resources to facilitate clinical decision-making. T L T L L
T T L L
T T L L
T T L T L L
T T L T L T L
PTS: 1
6. ANS: D
To assist in clinical decision-making, a number of evidence-based resources have been developed to assist the clinician.
T L L
T T L L
T L
T L
T L
T L
T L
T L
T T L L
T L
T L
T T L T L
TResources, such as algorithms and clinical practice guidelines, assist in clinical reasoning when properly applied.
L L
T T L T L L
T L
T L
T L
T L
T T L L
T L
T L
T L
T L
T
PTS: 1
7. ANS: A
The sensitivity of a diagnostic study is the percentage of individuals with the target condition who show an abnormal, or positive,
L
T L
T L
T L
T L
T L
T L
T L
T T L L
T L
T L
T L
T L
T L
T L
T L
T L
T L
T L
T
Tresult. A high sensitivity indicates that a greater percentage of persons with the given condition will have an abnormal result.
L L
T L
T L
T L
T L
T T L L
T L
T T L T L L
T L
T L
T T L T L L
T T L T L L
T
PTS: 1
8. ANS: B
The specificity of a diagnostic study is the percentage of normal, healthy individuals who have a normal result. The greater the
T L T L T L L
T L
T L
T T L T L L
T L
T L
T T L L
T L
T L
T T L T L L
T L
T T L
Tspecificity, the greater the percentage of individuals who will have negative, or normal, results if they do not have the target
L T L L
T L
T L
T T L T L L
T T L T L L
T T L T L L
T L
T L
T T L T L T L T L L
T
Tcondition.
L
PTS: 1
9. ANS: A
The likelihood ratio is the probability that a positive test result will be associated with a person who has the target condition and
T L T L L
T L
T L
T T L L
T L
T L
T L
T L
T T L L
T L
T L
T L
T L
T L
T L
T L
T L
T L
T
Ta negative result will be associated with a healthy person. A likelihood ratio above 1 indicates that a positive result is
L T L T L L
T T L L
T T L L
T T L T L L
T TL T L L
T T L T L T L T L L
T T L L
T
Tassociated with the disease; a likelihood ratio less than 1 indicates that a negative result is associated with an absence of the
L T L L
T L
T L
T L
T T L L
T L
T L
T L
T L
T L
T T L L
T L
T L
T T L T L L
T L
T L
T
Tdisease.
L
Downloaded by Anna Maina () L
T L
T L
T L
T
, lOMoAR T L cPSD|
T L
12263423
PTS: 1
10. ANS: B
Clinical decision (or prediction) rules provide another support for clinical reasoning. Clinical decision rules are evidence-based
L
T L
T L
T L
T L
T L
T L
T L
T L
T L
T L
T L
T L
T L
T L
T
L
Tresources that provide probabilistic statements regarding the likelihood that a condition exists if certain variables are met
L
T L
T L
T L
T L
T L
T T L L
T L
T T L L
T L
T L
T L
T L
T L
T
L
Twith regard to the prognosis of patients with specific findings. Decision rules use mathematical models and are specific to
L
T L
T L
T L
T L
T T L L
T L
T L
T L
T T L L
T L
T L
T L
T L
T L
T T L
L
Tcertain situations, settings, and/or patient characteristics.
L
T L
T L
T L
T L
T
PTS: 1
Downloaded by Anna Maina ()
L
T L
T L
T L
T
, lOMoAR T L cPSD|
T L 12263423
Chapter 2. Evidence-based health screening
L
T T L L
T L
T
Multiple Choice
T L
Identify the choice that best completes the statement or answers the question.
L
T L
T L
T L
T L
T L
T L
T L
T L
T L
T L
T
1. The first step in the genomic assessment of a patient is obtaining information regarding:
L
T L
T L
T L
T L
T L
T L
T L
T L
T L
T TL L
T L
T
A. Family history L
T
B. Environmental exposures L
T
C. Lifestyle and behaviors L
T L
T
D. Current medications L
T
2. An affected individual who manifests symptoms of a particular condition through whom a family with a genetic
L
T L
T T L T L L
T L
T L
T L
T L
T L
T L
T L
T L
T L
T L
T L
T
disorder is ascertained is called a(n):
L
T L
T T L L
T T L T L
A. Consultand
B. Consulband
C. Index patient L
T
D. Proband
3. An autosomal dominant disorder involves the:
L
T T L L
T L
T L
T
A. X chromosome
L
T
B. Y chromosome
L
T
C. Mitochondrial DNA L
T
D. Non-sex chromosomes L
T
4. To illustrate a union between two second cousin family members in a pedigree, draw:
L
T L
T L
T L
T L
T L
T T L L
T L
T L
T L
T L
T L
T
A. Arrows pointing to the male and female T L L
T L
T L
T T L L
T
B. Brackets around the male and female T L L
T L
T L
T L
T
C. Double horizontal lines between the male and female
L
T L
T L
T L
T T L L
T L
T
D. Circles around the male and female L
T L
T L
T L
T L
T
5. To illustrate two family members in an adoptive relationship in a pedigree:
L
T L
T L
T L
T L
T L
T L
T L
T L
T L
T L
T
A. Arrows are drawn pointing to the male and female L
T L
T T L L
T L
T L
T L
T L
T
B. Brackets are drawn around the male and female L
T L
T T L L
T L
T L
T L
T
C. Double horizontal lines are drawn between the male and female
L
T L
T T L L
T L
T L
T L
T L
T L
T
D. Circles are drawn around the male and female
L
T L
T T L L
T L
T L
T L
T
6. When analyzing the pedigree for autosomal dominant disorders, it is common to see:
L
T L
T L
T L
T L
T L
T L
T L
T L
T L
T L
T L
T
A. Several generations of affected members T L L
T L
T L
T
B. Many consanguineous relationships
L
T L
T
C. More members of the maternal lineage affected than paternal
L
T T L L
T L
T L
T T L L
T L
T
D. More members of the paternal lineage affected than maternal
L
T L
T L
T L
T L
T L
T L
T L
T
7. In autosomal recessive (AR) disorders, individuals need:
L
T L
T L
T L
T L
T L
T
A. Only one mutated gene on the sex chromosomes to acquire the disease
L
T L
T L
T L
T T L L
T T L L
T L
T L
T L
T
B. Only one mutated gene to acquire the disease
L
T L
T T L T L L
T L
T L
T
C. Two mutated genes to acquire the disease
L
T L
T L
T L
T L
T L
T
D. Two mutated genes to become carriers
L
T L
T L
T L
T L
T
8. In autosomal recessive disorders, carriers have:
L
T T L L
T L
T L
T
A. Two mutated genes; one from each parent that cause disease
L
T L
T L
T L
T L
T L
T L
T L
T L
T
B. A mutation on a sex chromosome that causes a disease
L
T L
T T L L
T L
T T L L
T L
T L
T
C. A single gene mutation that causes the disease
L
T L
T T L L
T L
T L
T L
T
D. One copy of a gene mutation but not the disease
L
T L
T L
T T L L
T L
T L
T L
T L
T
9. With an autosomal recessive disorder, it is important that parents understand that if they both carry a mutation, the
L
T L
T L
T L
T L
T L
T L
T L
T L
T L
T L
T L
T L
T L
T L
T L
T L
T L
T
L
Tfollowing are the risks to each of their offspring (each pregnancy):
L
T L
T L
T L
T T L T L T L L
T L
T L
T
A. 50% chance that offspring will carry the disease
L
T L
T L
T L
T T L L
T L
T
B. 10% chance of offspring affected by disease
L
T L
T L
T T L L
T L
T
Downloaded by Anna Maina () L
T L
T L
T L
T