NUR 6501- Advanced Pharmacology Ex
] ] ] ]
am 1 Questions with 100% Correct Answ
] ] ] ] ] ]
ers (2025-2026)
]QU
]
Once ]you ]graduate ]from ]an ]NP ]program, ]in ]order ]to ]prescribe ]you'll ]need: ]- ]correct ]answer: ]-
Advanced ]nurse ]prescriber ]license
-DEA ]#
What ]is ]the ]purpose ]of ]a ]DEA ]#? ]- ]correct ]answer: ]Needed ]to ]prescribed ]scheduled ]drugs
Rules ]for ]prescribing ]Schedule ]II ]drugs: ]- ]correct ]answer: ]-Written ]script ]needed
-1 ]month ]supply ]only ]
-No ]refills
What ]is ]the ]PDMP? ]- ]correct ]answer: ]Prescription ]Drug ]Monitoring ]Program
Used ]to ]effectively ]track ]patient's ]controlled ]substance ]uses ]across ]different ]health ]facilities ]
(in ]the ]same ]state)
What ]are ]clinical ]practice ]guidelines? ]- ]correct ]answer: ]Recommendations ]that ]are ]intended ]to ]o
ptimize ]patient ]care ]that ]are ]informed ]by ]a ]systematic ]review ]of ]the ]evidence ]and ]an ]assessmen
t ]of ]the ]benefits/harms ]of ]alternative ]care ]practices
Ex: ]sepsis, ]CAP
Common ]causes ]of ]medication ]errors: ]- ]correct ]answer: ]-Illegible ]writing
-Drug ]names ]that ]sound ]alike
,-Medications ]that ]look ]alike
-Administering ]a ]drug ]with ]the ]wrong ]route
What ]is ]pharmacokinetics? ]What ]are ]its ]4 ]categories? ]- ]correct ]answer: ]What ]the ]body ]does ]to ]t
he ]drug
1. ]Absorption
2. ]Metabolism
3. ]Distribution
4. ]Excretion
Quickest ]route ]of ]absorption? ]Slowest? ]- ]correct ]answer: ]IV ]= ]quickest ]
IM ]= ]slowest
What ]is ]the ]most ]common ]way ]drugs ]pass ]through ]cell ]membranes? ]- ]correct ]answer: ]Passive ]di
ffusion
What ]characteristics ]of ]a ]drug ]allow ]it ]to ]pass ]most ]quickly ]through ]cell ]membranes ]
(usually ]through ]passive ]diffusion)? ]- ]correct ]answer: ]Small, ]uncharged ]
(unionized), ]lipid ]soluble--pass ]through ]membrane ]without ]any ]energy
What ]does ]it ]mean ]when ]a ]drug ]is ]ionized? ]- ]correct ]answer: ]It ]means ]that ]the ]drug ]is ]stuck ]in ]th
e ]compartment ]it ]was ]ionized ]in ]and ]has ]to ]be ]moved ]to ]the ]next ]compartment ]
(cannot ]be ]absorbed ]into ]the ]bloodstream)
Where ]do ]weak ]acids ]absorb? ]- ]correct ]answer: ]Stomach
Where ]do ]weak ]bases ]absorb? ]- ]correct ]answer: ]Small ]intestine
,pH ]of ]stomach: ]- ]correct ]answer: ]2-4
pH ]of ]small ]intestine: ]- ]correct ]answer: ]6-7
pH ]of ]large ]intestine: ]- ]correct ]answer: ]6-7
pH ]of ]bloodstream: ]- ]correct ]answer: ]7.35-7.45
pH ]of ]bladder: ]- ]correct ]answer: ]5-8
pH ]of ]breastmilk: ]- ]correct ]answer: ]7.1
Where ]will ]a ]drug ]absorb ]if ]it ]is ]a ]weak ]base ]that ]ionizes ]at ]a ]pH ]of ]4 ]and ]lower? ]- ]correct ]answe
r: ]In ]the ]small ]intestine ](since ]the ]stomach ]has ]a ]pH ]of ]2-
4, ]so ]the ]drug ]will ]become ]ionized ]and ]move ]to ]the ]small ]intestine ]where ]it ]will ]be ]able ]to ]absor
b ]into ]the ]bloodstream)
How ]can ]we ]manipulate ]the ]urine ]pH ]in ]cases ]of ]overdose? ]- ]correct ]answer: ]Drugs ]that ]are ]wea
k ]acids ](aspirin) ]can ]be ]trapped ]and ]excreted ]through ]the ]urine. ]
We ]raise ]pH ]of ]the ]urine ]
(with ]sodium ]bicarb) ]to ]force ]the ]drug ]to ]ionize ]and ]allow ]it ]to ]be ]excreted, ]not ]reabsorbed ]thro
ugh ]the ]bloodstream.
What ]is ]distribution? ]- ]correct ]answer: ]How ]a ]drug ]will ]be ]transported ]to ]the ]tissues ]it ]needs ]to ]
go ]to ]in ]order ]for ]it ]to ]exert ]its ]effects
, Drug ]factors ]related ]to ]distribution: ]- ]correct ]answer: ]-Lipid ]solubility ]
-Molecular ]size
-Degree ]of ]ionization ]
-Duration ]of ]action
-Cellular ]binding
-Therapeutic ]effects ]
-Toxic ]effects
(lipid ]soluble, ]small, ]and ]non-ionized ]drugs ]will ]distribute ]more ]quickly)
Body ]factors ]related ]to ]distribution: ]- ]correct ]answer: ]-Vascularity ]
(poor ]perfusion, ]disruption ]of ]blood ]flow ]due ]to ]trauma--difficulty ]distributing)
-Blood ]barriers ](blood-brain-barrier ]can ]be ]problematic ]if ]we ]need ]to ]get ]drugs ]to ]the ]brain--
will ]need ]very ]high ]dosing ]since ]only ]a ]small ]amount ]of ]the ]drug ]will ]get ]through)
-Transport ]mechanisms ]
-Plasma ]binding ]proteins ]
-Disease ]states
-Volume ]of ]distribution
-Drug ]interactions
What ]is ]the ]key ]plasma ]protein ]involved ]with ]protein ]binding ]for ]medications? ]- ]correct ]answer: ]
Albumin
Why ]do ]we ]monitor ]albumin? ]- ]correct ]answer: ]Indicative ]of ]nutritional ]status ]and ]how ]well ]prot
ein-bound ]drugs ]will ]be ]transported ]to ]their ]target ]locations
What ]happens ]to ]the ]therapeutic ]effect ]of ]a ]drug ]when ]the ]patient ]is ]elderly ]and ]has ]very ]low ]le
vels ]of ]albumin? ]- ]correct ]answer: ]The ]drug ]does ]not ]bind ]to ]the ]protein ]
] ] ] ]
am 1 Questions with 100% Correct Answ
] ] ] ] ] ]
ers (2025-2026)
]QU
]
Once ]you ]graduate ]from ]an ]NP ]program, ]in ]order ]to ]prescribe ]you'll ]need: ]- ]correct ]answer: ]-
Advanced ]nurse ]prescriber ]license
-DEA ]#
What ]is ]the ]purpose ]of ]a ]DEA ]#? ]- ]correct ]answer: ]Needed ]to ]prescribed ]scheduled ]drugs
Rules ]for ]prescribing ]Schedule ]II ]drugs: ]- ]correct ]answer: ]-Written ]script ]needed
-1 ]month ]supply ]only ]
-No ]refills
What ]is ]the ]PDMP? ]- ]correct ]answer: ]Prescription ]Drug ]Monitoring ]Program
Used ]to ]effectively ]track ]patient's ]controlled ]substance ]uses ]across ]different ]health ]facilities ]
(in ]the ]same ]state)
What ]are ]clinical ]practice ]guidelines? ]- ]correct ]answer: ]Recommendations ]that ]are ]intended ]to ]o
ptimize ]patient ]care ]that ]are ]informed ]by ]a ]systematic ]review ]of ]the ]evidence ]and ]an ]assessmen
t ]of ]the ]benefits/harms ]of ]alternative ]care ]practices
Ex: ]sepsis, ]CAP
Common ]causes ]of ]medication ]errors: ]- ]correct ]answer: ]-Illegible ]writing
-Drug ]names ]that ]sound ]alike
,-Medications ]that ]look ]alike
-Administering ]a ]drug ]with ]the ]wrong ]route
What ]is ]pharmacokinetics? ]What ]are ]its ]4 ]categories? ]- ]correct ]answer: ]What ]the ]body ]does ]to ]t
he ]drug
1. ]Absorption
2. ]Metabolism
3. ]Distribution
4. ]Excretion
Quickest ]route ]of ]absorption? ]Slowest? ]- ]correct ]answer: ]IV ]= ]quickest ]
IM ]= ]slowest
What ]is ]the ]most ]common ]way ]drugs ]pass ]through ]cell ]membranes? ]- ]correct ]answer: ]Passive ]di
ffusion
What ]characteristics ]of ]a ]drug ]allow ]it ]to ]pass ]most ]quickly ]through ]cell ]membranes ]
(usually ]through ]passive ]diffusion)? ]- ]correct ]answer: ]Small, ]uncharged ]
(unionized), ]lipid ]soluble--pass ]through ]membrane ]without ]any ]energy
What ]does ]it ]mean ]when ]a ]drug ]is ]ionized? ]- ]correct ]answer: ]It ]means ]that ]the ]drug ]is ]stuck ]in ]th
e ]compartment ]it ]was ]ionized ]in ]and ]has ]to ]be ]moved ]to ]the ]next ]compartment ]
(cannot ]be ]absorbed ]into ]the ]bloodstream)
Where ]do ]weak ]acids ]absorb? ]- ]correct ]answer: ]Stomach
Where ]do ]weak ]bases ]absorb? ]- ]correct ]answer: ]Small ]intestine
,pH ]of ]stomach: ]- ]correct ]answer: ]2-4
pH ]of ]small ]intestine: ]- ]correct ]answer: ]6-7
pH ]of ]large ]intestine: ]- ]correct ]answer: ]6-7
pH ]of ]bloodstream: ]- ]correct ]answer: ]7.35-7.45
pH ]of ]bladder: ]- ]correct ]answer: ]5-8
pH ]of ]breastmilk: ]- ]correct ]answer: ]7.1
Where ]will ]a ]drug ]absorb ]if ]it ]is ]a ]weak ]base ]that ]ionizes ]at ]a ]pH ]of ]4 ]and ]lower? ]- ]correct ]answe
r: ]In ]the ]small ]intestine ](since ]the ]stomach ]has ]a ]pH ]of ]2-
4, ]so ]the ]drug ]will ]become ]ionized ]and ]move ]to ]the ]small ]intestine ]where ]it ]will ]be ]able ]to ]absor
b ]into ]the ]bloodstream)
How ]can ]we ]manipulate ]the ]urine ]pH ]in ]cases ]of ]overdose? ]- ]correct ]answer: ]Drugs ]that ]are ]wea
k ]acids ](aspirin) ]can ]be ]trapped ]and ]excreted ]through ]the ]urine. ]
We ]raise ]pH ]of ]the ]urine ]
(with ]sodium ]bicarb) ]to ]force ]the ]drug ]to ]ionize ]and ]allow ]it ]to ]be ]excreted, ]not ]reabsorbed ]thro
ugh ]the ]bloodstream.
What ]is ]distribution? ]- ]correct ]answer: ]How ]a ]drug ]will ]be ]transported ]to ]the ]tissues ]it ]needs ]to ]
go ]to ]in ]order ]for ]it ]to ]exert ]its ]effects
, Drug ]factors ]related ]to ]distribution: ]- ]correct ]answer: ]-Lipid ]solubility ]
-Molecular ]size
-Degree ]of ]ionization ]
-Duration ]of ]action
-Cellular ]binding
-Therapeutic ]effects ]
-Toxic ]effects
(lipid ]soluble, ]small, ]and ]non-ionized ]drugs ]will ]distribute ]more ]quickly)
Body ]factors ]related ]to ]distribution: ]- ]correct ]answer: ]-Vascularity ]
(poor ]perfusion, ]disruption ]of ]blood ]flow ]due ]to ]trauma--difficulty ]distributing)
-Blood ]barriers ](blood-brain-barrier ]can ]be ]problematic ]if ]we ]need ]to ]get ]drugs ]to ]the ]brain--
will ]need ]very ]high ]dosing ]since ]only ]a ]small ]amount ]of ]the ]drug ]will ]get ]through)
-Transport ]mechanisms ]
-Plasma ]binding ]proteins ]
-Disease ]states
-Volume ]of ]distribution
-Drug ]interactions
What ]is ]the ]key ]plasma ]protein ]involved ]with ]protein ]binding ]for ]medications? ]- ]correct ]answer: ]
Albumin
Why ]do ]we ]monitor ]albumin? ]- ]correct ]answer: ]Indicative ]of ]nutritional ]status ]and ]how ]well ]prot
ein-bound ]drugs ]will ]be ]transported ]to ]their ]target ]locations
What ]happens ]to ]the ]therapeutic ]effect ]of ]a ]drug ]when ]the ]patient ]is ]elderly ]and ]has ]very ]low ]le
vels ]of ]albumin? ]- ]correct ]answer: ]The ]drug ]does ]not ]bind ]to ]the ]protein ]
