Nsg 533 ADVANCED PHARMACOLOGY TEST 1
WEEK 4 QUESTION WITH VERIFIED ANSWERS
Which of the following SSRIs requires up to a 5-
vb vb vb vb vb vb vb vb vb
week washout period because of the long half-life of its potent active metabolite?
vb vb vb vb vb vb vb vb vb vb vb vb
A. Escitalopram
B. Fluvoxamine
C. Fluoxetine
D. Sertraline - ✔✔C vb vb
Which of the following symptoms is most likely to improve within approximately 1 week of
vb vb vb vb vb vb vb vb vb vb vb vb vb vb vb
starting treatment? vb
A. Depressed mood vb
B. Suicidal thoughts vb
C. Anhedonia
D. Sleep - ✔✔D vb vb
Of the following combinations of medications, which one would you want to avoid?
vb vb vb vb vb vb vb vb vb vb vb vb
A. Fluoxetine-lithium
B. Fluoxetine-phenelzine
C. Citalopram-valproic acid vb
D. Citalopram-aripiprazole - ✔✔B vb vb
A 26-year-
vb
old man with a history of depression has been taking sertraline 200 mg/day for 12 weeks with no response.
vb vb vb vb vb vb vb vb vb vb vb vb vb vb vb vb vb vb vb
The patient has no other complications. The physician asks for your recommendation. The most reasonab
vb vb vb vb vb vb vb vb vb vb vb vb vb vb
le recommendation would be to:
vb vb vb vb
A. Increase sertraline vb
B. Add fluoxetine vb
, C. Switch to amitriptyline vb vb
D. Change to venlafaxine vb vb
E. Decrease sertraline - ✔✔D vb vb vb
Which of the following is a dangerous combination?
vb vb vb vb vb vb vb
A. MAOI-lorazepam
B. MAOI-acetaminophen
C. MAOI-meperidine
D. MAOI-ziprasidone - ✔✔C vb vb
A 23-year-old married white woman comes to the outpatient psychiatric clinic
vb vb vb vb vb vb vb vb vb vb
complaining of decreased sleep, decreased appetite, decreased concentration, depressed m
vb vb vb vb vb vb vb vb vb
ood, thoughts of death, and lack of interest in activities for 6 weeks' duration. She has no hi
vb vb vb vb vb vb vb vb vb vb vb vb vb vb vb vb vb
story of psychiatric illness and takes no medications except for Ortho-Tri Cyclen Lo
vb vb vb vb vb vb vb vb vb vb vb vb
daily. Based upon the patients symptoms, choose the best medication to treat this patient.
vb vb vb vb vb vb vb vb vb vb vb vb vb
A. Nefazodone 100 mg po twice daily vb vb vb vb vb
B. Paroxetine 20 mg po daily vb vb vb vb
C. St. John's wort 300 mg po three times daily
vb vb vb vb vb vb vb vb
D. Amitriptyline 25 mg at bedtime - ✔✔B vb vb vb vb vb vb
A 36-year-old man is admitted to the hospital for a severe methicillin-
vb vb vb vb vb vb vb vb vb vb vb
resistant Staphylococcus aureus diabetic foot infection and is started on linezolid 600 mg IV every 12 hou
vb vb vb vb vb vb vb vb vb vb vb vb vb vb vb vb
rs. His medication profile includes paroxetine 40 mg every morning, trazodone 100 mg at bedtime as nee
vb vb vb vb vb vb vb vb vb vb vb vb vb vb vb vb
ded for sleep, and metformin 1000 mg po twice daily. After 3
vb vb vb vb vb vb vb vb vb vb vb
days on these medications, the patient becomes agitated, confused, and diaphoretic and develops myoclo
vb vb vb vb vb vb vb vb vb vb vb vb vb
nic jerks. Which of the following is the most likely diagnosis?
vb vb vb vb vb vb vb vb vb vb
A. Overdose of metformin vb vb
B. Bacterial meningitis vb
C. Neuroleptic malignant syndrome vb vb
D. Serotonin syndrome - ✔✔D vb vb vb
WEEK 4 QUESTION WITH VERIFIED ANSWERS
Which of the following SSRIs requires up to a 5-
vb vb vb vb vb vb vb vb vb
week washout period because of the long half-life of its potent active metabolite?
vb vb vb vb vb vb vb vb vb vb vb vb
A. Escitalopram
B. Fluvoxamine
C. Fluoxetine
D. Sertraline - ✔✔C vb vb
Which of the following symptoms is most likely to improve within approximately 1 week of
vb vb vb vb vb vb vb vb vb vb vb vb vb vb vb
starting treatment? vb
A. Depressed mood vb
B. Suicidal thoughts vb
C. Anhedonia
D. Sleep - ✔✔D vb vb
Of the following combinations of medications, which one would you want to avoid?
vb vb vb vb vb vb vb vb vb vb vb vb
A. Fluoxetine-lithium
B. Fluoxetine-phenelzine
C. Citalopram-valproic acid vb
D. Citalopram-aripiprazole - ✔✔B vb vb
A 26-year-
vb
old man with a history of depression has been taking sertraline 200 mg/day for 12 weeks with no response.
vb vb vb vb vb vb vb vb vb vb vb vb vb vb vb vb vb vb vb
The patient has no other complications. The physician asks for your recommendation. The most reasonab
vb vb vb vb vb vb vb vb vb vb vb vb vb vb
le recommendation would be to:
vb vb vb vb
A. Increase sertraline vb
B. Add fluoxetine vb
, C. Switch to amitriptyline vb vb
D. Change to venlafaxine vb vb
E. Decrease sertraline - ✔✔D vb vb vb
Which of the following is a dangerous combination?
vb vb vb vb vb vb vb
A. MAOI-lorazepam
B. MAOI-acetaminophen
C. MAOI-meperidine
D. MAOI-ziprasidone - ✔✔C vb vb
A 23-year-old married white woman comes to the outpatient psychiatric clinic
vb vb vb vb vb vb vb vb vb vb
complaining of decreased sleep, decreased appetite, decreased concentration, depressed m
vb vb vb vb vb vb vb vb vb
ood, thoughts of death, and lack of interest in activities for 6 weeks' duration. She has no hi
vb vb vb vb vb vb vb vb vb vb vb vb vb vb vb vb vb
story of psychiatric illness and takes no medications except for Ortho-Tri Cyclen Lo
vb vb vb vb vb vb vb vb vb vb vb vb
daily. Based upon the patients symptoms, choose the best medication to treat this patient.
vb vb vb vb vb vb vb vb vb vb vb vb vb
A. Nefazodone 100 mg po twice daily vb vb vb vb vb
B. Paroxetine 20 mg po daily vb vb vb vb
C. St. John's wort 300 mg po three times daily
vb vb vb vb vb vb vb vb
D. Amitriptyline 25 mg at bedtime - ✔✔B vb vb vb vb vb vb
A 36-year-old man is admitted to the hospital for a severe methicillin-
vb vb vb vb vb vb vb vb vb vb vb
resistant Staphylococcus aureus diabetic foot infection and is started on linezolid 600 mg IV every 12 hou
vb vb vb vb vb vb vb vb vb vb vb vb vb vb vb vb
rs. His medication profile includes paroxetine 40 mg every morning, trazodone 100 mg at bedtime as nee
vb vb vb vb vb vb vb vb vb vb vb vb vb vb vb vb
ded for sleep, and metformin 1000 mg po twice daily. After 3
vb vb vb vb vb vb vb vb vb vb vb
days on these medications, the patient becomes agitated, confused, and diaphoretic and develops myoclo
vb vb vb vb vb vb vb vb vb vb vb vb vb
nic jerks. Which of the following is the most likely diagnosis?
vb vb vb vb vb vb vb vb vb vb
A. Overdose of metformin vb vb
B. Bacterial meningitis vb
C. Neuroleptic malignant syndrome vb vb
D. Serotonin syndrome - ✔✔D vb vb vb
