NSG 511: Exam 4 Questions and Correct Answers
estrogen functions: sexual maturity
development and maintenance of female secondary sex characteristics
estrogen functions: reproductive cycle
- follicular (ending with ovulation at day 14) and luteal phases (ending with menstruation)
- proliferation of uterine endothelium and endocervical mucus production
estrogen functions: bones
maintenance of bone health by blocking the actions of osteoclasts
estrogen functions: cholesterol
favors beneficial ratio of HDL:LDL (considered cardioprotective)
estrogen functions: coagulation
complex, but clinically considered thrombogenic
progesterone functions
reproductive cycle - luteal phase - secretory phase and hypertrophy of the endometrium in
preparation for implantation of the zygote
progesterone - no implantation
corpus luteum breaks down, progesterone declines, and endometrium sheds (menstruation)
progesterone - implantation
corpus luteum and placenta synthesize and release progesterone to support the endometrial
lining and the pregnancy
,uses of estrogen and progesterone
- contraception
- menopausal hormone therapy
- gender affirmation and transgender health
- acne
- female hypogonadism
estrogen treating acne
antibiotics used to treat organism and estrogen and/or anti-androgens are used to block the
influence of testosterone
estrogen treating hypogonadism
in absence of estrogen therapy, secondary sex characteristics will not develop - estrogen
administered exogenously
composition of combination pills for contraception
estradiol
AND
1 of 4 generations of progestins to prevent ovulation
combination pills MOA
- 28 day cycle (21 active medication and 7 placebo)
- placebo pills initiate menstruation
- prevent ovulation
, 2 ways to eliminate menstruation
1) take an extended cycle oral contraception
2) take a monophastic oral contraceptive and skip placebo pills
example of extended cycle oral contraceptive
LoSeasonique
- 20 mcg ethinyl estradiol
- 0.1 mg levonorgestrel
$$$
example of monophasic oral contraceptive
Lutera
- 20 mcg ethinyl estradiol
- 0.1 mg levonorgestrel
cheaper
initiation criteria for combination pills
- if within 5 days of starting menstruation, no backup method needed
- if greater than 5 days of starting menstruation, 7 days of abstinence/backup method
estrogen side effects
nausea, breast tenderness, swelling
progestin side effects
appetite and weight gain, fatigue, depression
estrogen functions: sexual maturity
development and maintenance of female secondary sex characteristics
estrogen functions: reproductive cycle
- follicular (ending with ovulation at day 14) and luteal phases (ending with menstruation)
- proliferation of uterine endothelium and endocervical mucus production
estrogen functions: bones
maintenance of bone health by blocking the actions of osteoclasts
estrogen functions: cholesterol
favors beneficial ratio of HDL:LDL (considered cardioprotective)
estrogen functions: coagulation
complex, but clinically considered thrombogenic
progesterone functions
reproductive cycle - luteal phase - secretory phase and hypertrophy of the endometrium in
preparation for implantation of the zygote
progesterone - no implantation
corpus luteum breaks down, progesterone declines, and endometrium sheds (menstruation)
progesterone - implantation
corpus luteum and placenta synthesize and release progesterone to support the endometrial
lining and the pregnancy
,uses of estrogen and progesterone
- contraception
- menopausal hormone therapy
- gender affirmation and transgender health
- acne
- female hypogonadism
estrogen treating acne
antibiotics used to treat organism and estrogen and/or anti-androgens are used to block the
influence of testosterone
estrogen treating hypogonadism
in absence of estrogen therapy, secondary sex characteristics will not develop - estrogen
administered exogenously
composition of combination pills for contraception
estradiol
AND
1 of 4 generations of progestins to prevent ovulation
combination pills MOA
- 28 day cycle (21 active medication and 7 placebo)
- placebo pills initiate menstruation
- prevent ovulation
, 2 ways to eliminate menstruation
1) take an extended cycle oral contraception
2) take a monophastic oral contraceptive and skip placebo pills
example of extended cycle oral contraceptive
LoSeasonique
- 20 mcg ethinyl estradiol
- 0.1 mg levonorgestrel
$$$
example of monophasic oral contraceptive
Lutera
- 20 mcg ethinyl estradiol
- 0.1 mg levonorgestrel
cheaper
initiation criteria for combination pills
- if within 5 days of starting menstruation, no backup method needed
- if greater than 5 days of starting menstruation, 7 days of abstinence/backup method
estrogen side effects
nausea, breast tenderness, swelling
progestin side effects
appetite and weight gain, fatigue, depression
