ONCC OCN PRACTICE EXAMINATION 200 Practice Questions with Verified
Answers & Rationales.
ONCC OCN Practice Examination: 200 Practice Questions with Answers &
Rationales
Welcome to this comprehensive OCN® practice examination. This resource
provides 200 multiple-choice questions designed to reflect the style, content, and
difficulty of the actual ONCC Oncology Certified Nurse exam. Questions are
organized by domain based on the official OCN Test Content Outline.
DOMAIN I: HEALTH PROMOTION, SCREENING, AND EARLY DETECTION (6%)
Questions 1-12
1. A 52-year-old female patient with no family history of breast cancer asks about
screening mammography. According to current guidelines, which
recommendation is most appropriate?
A) Begin screening at age 40 with annual mammograms
B) Begin screening at age 50 with mammograms every 2 years
C) Begin screening at age 45 with annual mammograms until age 54, then every 2
years
,D) Screening is not recommended until age 55
Answer: C) Begin screening at age 45 with annual mammograms until age 54,
then every 2 years
Rationale: Current guidelines recommend that women at average risk begin
screening mammography at age 45, with annual screening from ages 45-54 and
biennial screening starting at age 55. Women ages 40-44 should have the option
to begin screening based on individual preference and shared decision-making.
This patient has no risk factors, making average-risk guidelines appropriate.
2. A 65-year-old male patient with a 40-pack-year smoking history asks about lung
cancer screening. Which criteria must be met for him to be a candidate for low-
dose CT screening?
A) Age 50-80 with 20 pack-year history and current smoker
B) Age 55-77 with 30 pack-year history and current or former smoker who quit
within 15 years
,C) Age 50-80 with 30 pack-year history and current or former smoker who quit
within 10 years
D) Any patient with a 20 pack-year history regardless of age
Answer: B) Age 55-77 with 30 pack-year history and current or former smoker
who quit within 15 years
Rationale: The USPSTF recommends annual screening for lung cancer with low-
dose CT in adults aged 55-77 years who have a 30 pack-year smoking history and
are current smokers or have quit within the past 15 years. This patient meets all
criteria, making him an appropriate candidate for screening.
3. A 50-year-old African American male is being seen for routine health
maintenance. What recommendation should the nurse provide regarding
prostate cancer screening?
A) Begin screening at age 50 with annual PSA and DRE
B) Begin screening at age 45 with shared decision-making
, C) Screening is not recommended for African American men
D) Begin screening at age 40 with annual PSA
Answer: B) Begin screening at age 45 with shared decision-making
Rationale: African American men and those with a family history of prostate
cancer are at higher risk and should begin discussions about screening at age 45.
Shared decision-making between the patient and provider is essential,
considering the risks and benefits of PSA screening. Age 50 is the recommended
starting point for average-risk men.
4. A 58-year-old female patient with a first-degree relative diagnosed with
colorectal cancer at age 55 asks about screening recommendations. When should
this patient begin colorectal cancer screening?
A) Age 50
B) Age 45
C) Age 40
Answers & Rationales.
ONCC OCN Practice Examination: 200 Practice Questions with Answers &
Rationales
Welcome to this comprehensive OCN® practice examination. This resource
provides 200 multiple-choice questions designed to reflect the style, content, and
difficulty of the actual ONCC Oncology Certified Nurse exam. Questions are
organized by domain based on the official OCN Test Content Outline.
DOMAIN I: HEALTH PROMOTION, SCREENING, AND EARLY DETECTION (6%)
Questions 1-12
1. A 52-year-old female patient with no family history of breast cancer asks about
screening mammography. According to current guidelines, which
recommendation is most appropriate?
A) Begin screening at age 40 with annual mammograms
B) Begin screening at age 50 with mammograms every 2 years
C) Begin screening at age 45 with annual mammograms until age 54, then every 2
years
,D) Screening is not recommended until age 55
Answer: C) Begin screening at age 45 with annual mammograms until age 54,
then every 2 years
Rationale: Current guidelines recommend that women at average risk begin
screening mammography at age 45, with annual screening from ages 45-54 and
biennial screening starting at age 55. Women ages 40-44 should have the option
to begin screening based on individual preference and shared decision-making.
This patient has no risk factors, making average-risk guidelines appropriate.
2. A 65-year-old male patient with a 40-pack-year smoking history asks about lung
cancer screening. Which criteria must be met for him to be a candidate for low-
dose CT screening?
A) Age 50-80 with 20 pack-year history and current smoker
B) Age 55-77 with 30 pack-year history and current or former smoker who quit
within 15 years
,C) Age 50-80 with 30 pack-year history and current or former smoker who quit
within 10 years
D) Any patient with a 20 pack-year history regardless of age
Answer: B) Age 55-77 with 30 pack-year history and current or former smoker
who quit within 15 years
Rationale: The USPSTF recommends annual screening for lung cancer with low-
dose CT in adults aged 55-77 years who have a 30 pack-year smoking history and
are current smokers or have quit within the past 15 years. This patient meets all
criteria, making him an appropriate candidate for screening.
3. A 50-year-old African American male is being seen for routine health
maintenance. What recommendation should the nurse provide regarding
prostate cancer screening?
A) Begin screening at age 50 with annual PSA and DRE
B) Begin screening at age 45 with shared decision-making
, C) Screening is not recommended for African American men
D) Begin screening at age 40 with annual PSA
Answer: B) Begin screening at age 45 with shared decision-making
Rationale: African American men and those with a family history of prostate
cancer are at higher risk and should begin discussions about screening at age 45.
Shared decision-making between the patient and provider is essential,
considering the risks and benefits of PSA screening. Age 50 is the recommended
starting point for average-risk men.
4. A 58-year-old female patient with a first-degree relative diagnosed with
colorectal cancer at age 55 asks about screening recommendations. When should
this patient begin colorectal cancer screening?
A) Age 50
B) Age 45
C) Age 40
