NUR 2474 - Nursing Pharmacology
] ] ] ] ]
Questions and Correct Answers 2025-
] ] ] ] ]
2026
Absorption ]- ]correct ]answer: ]the ]process ]by ]which ]drug ]molecules ]move ]from ]their ]site ]of ]admi
nistration ]to ]the ]blood
Affinity ]- ]correct ]answer: ]the ]ability ]of ]some ]tissues ]to ]attract, ]accumulate ]and ]store ]drugs ]in ]hig
h ]concentrations ]relative ]to ]other ]tissues
blood-brain ]barrier ]- ]correct ]answer: ]Blood ]vessels ]
(capillaries) ]that ]selectively ]let ]certain ]substances ]enter ]the ]brain ]tissue ]and ]keep ]other ]substan
ces ]out
diffusion ]- ]correct ]answer: ]process ]by ]which ]molecules ]tend ]to ]move ]from ]an ]area ]where ]they ]a
re ]more ]concentrated ]to ]an ]area ]where ]they ]are ]less ]concentrated
distribution ]- ]correct ]answer: ]the ]transport ]of ]drugs ]throughout ]the ]body ]after ]they ]are ]absorbe
d
drug-
protein ]complexes ]- ]correct ]answer: ]formed ]when ]a ]drugh ]that ]binds ]reversibly ]to ]a ]plasma ]prot
ein, ]particularly ]albumin, ]that ]makes ]the ]drug ]unavailable ]for ]distribution ]to ]its ]site ]of ]action
enterohepatic ]recirculation ]- ]correct ]answer: ]recycling ]of ]drugs ]and ]other ]substances ]by ]the ]circ
ulation ]of ]bile ]through ]the ]intestine ]and ]liver
enzyme ]induction ]- ]correct ]answer: ]process ]by ]whick ]a ]drug ]increases ]the ]activity ]of ]the ]hepatic ]
microsomal ]enzymes
, excretion ]- ]correct ]answer: ]the ]process ]of ]removing ]substances ]from ]the ]body
first-pass ]effect ]- ]correct ]answer: ]mechanism ]whereby ]drugs ]are ]absorbed ]enter ]into ]the ]hepatic
]portal ]circulation ]and ]are ]inactivated ]by ]the ]liver ]before ]they ]reach ]the ]general ]circulation
fetal-
placental ]barrier ]- ]correct ]answer: ]special ]anatomic ]barrier ]that ]inhibits ]many ]chemicals ]and ]dru
gs ]from ]entering ]the ]fetus
hepatic ]microsomal ]enzyme ]system ]- ]correct ]answer: ]as ]it ]relates ]to ]phamacotherapy, ]liver ]enzy
mes ]that ]metabolize ]drugs ]as ]well ]as ]nutrients ]and ]other ]endogenous ]substances, ]sometimes ]ca
lled ]the ]P-450 ]System
isozymes ]- ]correct ]answer: ]multiple ]similar ]forms ]of ]an ]enzyme ]that ]perform ]slightly ]different ]m
etabolic ]functions
loading ]dose ]- ]correct ]answer: ]relatively ]large ]dose ]of ]a ]drug ]given ]at ]the ]beginning ]of ]treatment
]to ]rapidly ]obtain ]a ]therapeutic ]response
maintenance ]doses ]- ]correct ]answer: ]amount ]of ]drug ]that ]keeps ]the ]plasma ]drug ]concentration ]
in ]the ]therapeutic ]range
metabolism ]- ]correct ]answer: ]the ]process ]used ]by ]the ]body ]to ]chemically ]change ]a ]drug ]molecul
e, ]also ]called ]biotransformation
minimum ]effective ]concentration ]- ]correct ]answer: ]amount ]of ]drug ]required ]to ]produce ]a ]thera
peutic ]effect
] ] ] ] ]
Questions and Correct Answers 2025-
] ] ] ] ]
2026
Absorption ]- ]correct ]answer: ]the ]process ]by ]which ]drug ]molecules ]move ]from ]their ]site ]of ]admi
nistration ]to ]the ]blood
Affinity ]- ]correct ]answer: ]the ]ability ]of ]some ]tissues ]to ]attract, ]accumulate ]and ]store ]drugs ]in ]hig
h ]concentrations ]relative ]to ]other ]tissues
blood-brain ]barrier ]- ]correct ]answer: ]Blood ]vessels ]
(capillaries) ]that ]selectively ]let ]certain ]substances ]enter ]the ]brain ]tissue ]and ]keep ]other ]substan
ces ]out
diffusion ]- ]correct ]answer: ]process ]by ]which ]molecules ]tend ]to ]move ]from ]an ]area ]where ]they ]a
re ]more ]concentrated ]to ]an ]area ]where ]they ]are ]less ]concentrated
distribution ]- ]correct ]answer: ]the ]transport ]of ]drugs ]throughout ]the ]body ]after ]they ]are ]absorbe
d
drug-
protein ]complexes ]- ]correct ]answer: ]formed ]when ]a ]drugh ]that ]binds ]reversibly ]to ]a ]plasma ]prot
ein, ]particularly ]albumin, ]that ]makes ]the ]drug ]unavailable ]for ]distribution ]to ]its ]site ]of ]action
enterohepatic ]recirculation ]- ]correct ]answer: ]recycling ]of ]drugs ]and ]other ]substances ]by ]the ]circ
ulation ]of ]bile ]through ]the ]intestine ]and ]liver
enzyme ]induction ]- ]correct ]answer: ]process ]by ]whick ]a ]drug ]increases ]the ]activity ]of ]the ]hepatic ]
microsomal ]enzymes
, excretion ]- ]correct ]answer: ]the ]process ]of ]removing ]substances ]from ]the ]body
first-pass ]effect ]- ]correct ]answer: ]mechanism ]whereby ]drugs ]are ]absorbed ]enter ]into ]the ]hepatic
]portal ]circulation ]and ]are ]inactivated ]by ]the ]liver ]before ]they ]reach ]the ]general ]circulation
fetal-
placental ]barrier ]- ]correct ]answer: ]special ]anatomic ]barrier ]that ]inhibits ]many ]chemicals ]and ]dru
gs ]from ]entering ]the ]fetus
hepatic ]microsomal ]enzyme ]system ]- ]correct ]answer: ]as ]it ]relates ]to ]phamacotherapy, ]liver ]enzy
mes ]that ]metabolize ]drugs ]as ]well ]as ]nutrients ]and ]other ]endogenous ]substances, ]sometimes ]ca
lled ]the ]P-450 ]System
isozymes ]- ]correct ]answer: ]multiple ]similar ]forms ]of ]an ]enzyme ]that ]perform ]slightly ]different ]m
etabolic ]functions
loading ]dose ]- ]correct ]answer: ]relatively ]large ]dose ]of ]a ]drug ]given ]at ]the ]beginning ]of ]treatment
]to ]rapidly ]obtain ]a ]therapeutic ]response
maintenance ]doses ]- ]correct ]answer: ]amount ]of ]drug ]that ]keeps ]the ]plasma ]drug ]concentration ]
in ]the ]therapeutic ]range
metabolism ]- ]correct ]answer: ]the ]process ]used ]by ]the ]body ]to ]chemically ]change ]a ]drug ]molecul
e, ]also ]called ]biotransformation
minimum ]effective ]concentration ]- ]correct ]answer: ]amount ]of ]drug ]required ]to ]produce ]a ]thera
peutic ]effect