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NSG 5140 Midterm Exam Review/ Advanced Pathophysiology Questions and Correct Answers from Actual Exam 2026. A + SCORE.THE ULTIMATE STUDY GUIDE.pdf

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NSG 5140 Midterm Exam Review/ Advanced Pathophysiology Questions and Correct Answers from Actual Exam 2026. A + SCORE.THE ULTIMATE STUDY GUIDE.pdf

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NSG 5140 Midterm Exam Review: Advanced
Pathophysiology
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Terms in this set (236) Hide definitions




The sodium-potassium pump moves 3 Na⁺ ions out and 2 Sodium-Potassium Pump
K⁺ ions into the cell, creating an electrochemical gradient
essential for membrane potential.


Mitochondria are known as the 'powerhouse' of the cell Mitochondria
due to their role in oxidative phosphorylation and ATP
generation.


In metabolic acidosis, there is a loss of bicarbonate or Metabolic Acidosis Lab Values
accumulation of acids, lowering both bicarbonate and
pH.




B cells differentiate into plasma cells which produce B Lymphocytes
antibodies, central to humoral immunity.


Reversible injury often involves failure of ion pumps Hallmark of Reversible Cellular Injury
leading to water influx and cell swelling.

, IL-1 acts on the hypothalamus to raise the body Interleukin-1 (IL-1)
temperature set point, causing fever.


Type 1 DM is an autoimmune condition where T-cells Type 1 Diabetes Mellitus
destroy insulin-producing beta cells in the pancreas.


Redness (rubor) results from vasodilation and increased Cardinal Sign of Acute Inflammation
blood flow to the inflamed area.


Trisomy 21 leads to Down syndrome, characterized by Down Syndrome
developmental delays and distinct facial features.


In the brain, ischemic injury leads to enzymatic digestion Liquefactive Necrosis
of dead cells resulting in liquefactive necrosis.


IgM is the first antibody produced and is effective in IgM
agglutination and complement activation.


Oncogenes are mutated proto-oncogenes that drive Oncogene
unregulated cell proliferation.




Low potassium levels disturb the cardiac action potential, Hypokalemia
increasing the risk of arrhythmias.


SLE involves immune complex deposition (Type III), Type III Hypersensitivity
leading to widespread inflammation and tissue damage.


The primary motor cortex, located in the frontal lobe, Frontal Lobe
initiates voluntary movement.


Shock results in inadequate delivery of oxygen and Impaired tissue perfusion
nutrients to tissues, causing cellular dysfunction.


Asthma involves hyperresponsiveness, smooth muscle Bronchoconstriction and mucus production
constriction, and increased mucus, narrowing the airway.


Apoptosis is an orderly process for removing damaged Apoptosis
or unneeded cells without inflammation.


Plaque rupture leads to thrombus formation, blocking Atherosclerotic plaque rupture
coronary arteries and causing infarction.

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