VTNE PHARMACOLOGY
EXAM
High-Yield Qs & Answers with Feedback
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High-Yield Qs
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All drugs need to be stored and handled so that they are safe for the patient, client, and
veterinary staff. When handling drugs that are concidered cytotoxic or hazardous, personal
protective apparel (PPA) should be worn. With which of the following drugs is it imperative to
pay special attention to safe handling?
-Ascorbic Acid
-Metoclopramide
-Sucralfate
-Vincristine
-Metronidazole - CORRECT ANSWER -Vincristine is a chemotheraputic agent and PPA including
gloves, gowns, and a face shield should be worn when using this drug. Ascorbic acid is Vitamin C
and probably poses minimal risk when handling. Metronidazole and sucralfate are not
hazardous via handling.
An 11-year old male German shepherd dog with previously diagnosed dilated cardiomyopathy
(DCM) presents to your clinic following a dog fight. The dog is significantly aggressive and
resistant to handling. What medication should NOT be used to sedate this patient?
-Dexmedetomidine
-Atropine
-Midazolam
-Butorphanol
-Buprenorphine - CORRECT ANSWER -Dexmedetomidine should only be used in patients with
normal cardiac function as it can cause a significant reduction in cardiac output due to reduced
heart rate. It should be avoided whenever possible in patients that have compromised cardiac
function. Butorphanol and buprenorphine would be better options for sedation as these drugs
would not have as much effect on cardiac output and would provide some pain relief.
Midazolam can be used to sedate the patient via IM administration and, although it would not
provide any pain control, it would allow for safer handling of the patient. Atropine is not a
sedative, but an anticholinergic used most commonly to increase heart rate.
A Golden retriever ingests several tablespoons of antifreeze. This will cause the most damage to
what organ system?
-Cardiac
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-Renal
-Hepatic
-Gastrointestinal
-Nervous - CORRECT ANSWER -Renal
Ethylene glycol (EG), the primary ingredient in antifreeze, causes damage to the renal system
(kidneys). EG causes damage to the renal tubular epithelium, causing build up of oxalate crystals
in the renal tubules and metabolic acidosis.
Which is safe to put in the ears if the tympanum may be ruptured?
-Chlorhexidine
-Gentamicin
-Neomycin
-0.9% NaCl - CORRECT ANSWER -Saline (0.9% sodium chloride) is considered safe.
The others listed (especially aminoglycoside antibiotics) could potentially be ototoxic if the
eardrum is not intact.
Which of the following medications is commonly found over-the-counter (OTC)?
-Diphenhydramine
-Pimobendan
-Hydrocodone
-Doxycycline - CORRECT ANSWER -Diphenhydramine
The other name for diphenhydramine is Benadryl and can be found over-the-counter.
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Hydrocodone is commonly used as a cough suppressant in veterinary medicine and is a
controlled substance requiring a prescription.
Doxycycline (an antibiotic) and Pimobendan (a heart medication) are by prescription only.
How many milliliters of 50% dextrose should be added to a 100 ml solution of Lactated Ringer's
Solution to make it 2.5%?
0.5
ml
5
ml
10
ml
1
ml
50 ml - CORRECT ANSWER -To answer this question, the following formula should be
implemented:
C(1)V(1) = C(2)V(2)
C is the concentration
V is the volume
C(1) =0.5
V(1) = x
C(2) = 0.025
V(2) = 100 ml
0.5x = 0.025(100)
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