WALDEN UNIVERSITY NRS 6630
PSYCHOPHARMACOLOGY ADVANCED TEST MIDTERM
STUDY GUIDE QUESTIONS AND ANSWERS UPDATED
2026
Adverse effects of MAOIs include: - CORRECT ANS ***Serotonin syndrome and hypertensive
crisis
Due to inhibition of nicotinic (acetylcholine) receptors, this Atypical antidepressant is useful in
smoking cessation: - CORRECT ANS ***bupropion
Due to inhibition of nicotinic (acetylcholine) receptors, this Atypical antidepressant is useful in
smoking cessation: - CORRECT ANS ***bupropion
Due to it's noradrenergic (excitatory) effects, this Atypical Antidepressant may cause
tachycardia, insomnia, and a lower seizure threshold: - CORRECT ANS ***bupropion
Due to its action as an adrenergic antagonist this drug is the treatment of hypertensive crisis: -
CORRECT ANS ***Phentolamine
Due to its noradrenergic (excitatory) effects, this Atypical Antidepressant may cause
tachycardia, insomnia, and a lower seizure threshold: - CORRECT ANS ***bupropion
Due to this medications possible side effects of Agranulocytosis and subsequent risk for
infections, this Atypical Antipsychotic is only used if a client has not responded to other
Antipsychotics: - CORRECT ANS ***clozapine
Eight common Atypical Antipsychotics: - CORRECT ANS ***clozapine, olanzapine, quetiapine,
paliperidone, risperidone, lurasidone, ziprasidone, aripiprazole
,Excess accumulation of serotonin resulting in overstimulation of the nervous system - CORRECT
ANS ***Serotonin Syndrome
First line agent for Acute Mania: - CORRECT ANS ***Atypical Antipsychotics
First line therapy for MDD due to milder side effect profiles - CORRECT ANS ***SSRIs
Five Common side effects of SSRIs include - CORRECT ANS ***Anxiety, insomnia, GI distress,
sexual dysfunction (ED), SIADH
Five common SNRIs include - CORRECT ANS ***duloxetine, venlafaxine, desvenlafaxine,
milnacipran, levomilnacipran
Five main symptoms of hypertensive crisis: - CORRECT ANS ***hyperthermia, hypertension,
tachycardia, arrhythmias, agitation
Five other indications for Atypical Antipsychotics: - CORRECT ANS ***Bipolar disorder, OCD,
Anxiety, Depression, Tourette Syndrome
Foods and drinks rich in tyramine: - CORRECT ANS ***cheese, wine, beer, cured/smoked meats
For depressed individuals with anorexia, increased appetite and weight gain, are possibly
beneficial side effects of this Atypical Antidepressant: - CORRECT ANS ***mirtazapine
Function of the Mesocortical pathway: - CORRECT ANS ***emotions
Function of the Tuberoinfundibular pathway: - CORRECT ANS ***releases Dopamine to limit the
secretion of Prolactin
, Functions of the Mesolimbic pathway: - CORRECT ANS ***motivation and desire
Functions of the Nigrostriatal pathway: - CORRECT ANS ***controls involuntary movements
and coordination (contains motor neurons)
All SSRIs but paroxetine (D) are pregnancy category - CORRECT ANS ***C
Another pathway of the CNS that is rich in Dopamine receptors and is responsible for eating
behavior: - CORRECT ANS ***Medullary Periventricular
Another region of the CNS that is rich in Dopamine receptors and is responsible for initiating
the
When stimulated Alpha 2 receptors inhibit the activity of the presynaptic neuron and decrease
the release of these two neurotransmitters: - CORRECT ANS ***Norepinephrine and Serotonin
When stimulated Alpha 2 receptors inhibit the activity of the presynaptic neuron and decrease
the release of these two neurotransmitters: - CORRECT ANS ***Norepinephrine and Serotonin
When tyramine is not broken down, it increases the release of this neurotransmitter, which
causes hypertensive crisis: - CORRECT ANS ***Norepinephrine
When uninhibited, these two enzymes are responsible for breaking down tyramine: - CORRECT
ANS ***MAO-A and MAO-B
Which type of Antipsychotics are preferred? Typical (first-generation) or Atypical (second
generation): - CORRECT ANS ***Atypical (second generation)
Which Typical Antipsychotics have a stronger sedating effect but less extrapyramidal side
effects? Low potency or High potency Typical Antipsychotics: - CORRECT ANS ***Low potency
vomiting reflex: - CORRECT ANS ***Chemoreceptor trigger zone
PSYCHOPHARMACOLOGY ADVANCED TEST MIDTERM
STUDY GUIDE QUESTIONS AND ANSWERS UPDATED
2026
Adverse effects of MAOIs include: - CORRECT ANS ***Serotonin syndrome and hypertensive
crisis
Due to inhibition of nicotinic (acetylcholine) receptors, this Atypical antidepressant is useful in
smoking cessation: - CORRECT ANS ***bupropion
Due to inhibition of nicotinic (acetylcholine) receptors, this Atypical antidepressant is useful in
smoking cessation: - CORRECT ANS ***bupropion
Due to it's noradrenergic (excitatory) effects, this Atypical Antidepressant may cause
tachycardia, insomnia, and a lower seizure threshold: - CORRECT ANS ***bupropion
Due to its action as an adrenergic antagonist this drug is the treatment of hypertensive crisis: -
CORRECT ANS ***Phentolamine
Due to its noradrenergic (excitatory) effects, this Atypical Antidepressant may cause
tachycardia, insomnia, and a lower seizure threshold: - CORRECT ANS ***bupropion
Due to this medications possible side effects of Agranulocytosis and subsequent risk for
infections, this Atypical Antipsychotic is only used if a client has not responded to other
Antipsychotics: - CORRECT ANS ***clozapine
Eight common Atypical Antipsychotics: - CORRECT ANS ***clozapine, olanzapine, quetiapine,
paliperidone, risperidone, lurasidone, ziprasidone, aripiprazole
,Excess accumulation of serotonin resulting in overstimulation of the nervous system - CORRECT
ANS ***Serotonin Syndrome
First line agent for Acute Mania: - CORRECT ANS ***Atypical Antipsychotics
First line therapy for MDD due to milder side effect profiles - CORRECT ANS ***SSRIs
Five Common side effects of SSRIs include - CORRECT ANS ***Anxiety, insomnia, GI distress,
sexual dysfunction (ED), SIADH
Five common SNRIs include - CORRECT ANS ***duloxetine, venlafaxine, desvenlafaxine,
milnacipran, levomilnacipran
Five main symptoms of hypertensive crisis: - CORRECT ANS ***hyperthermia, hypertension,
tachycardia, arrhythmias, agitation
Five other indications for Atypical Antipsychotics: - CORRECT ANS ***Bipolar disorder, OCD,
Anxiety, Depression, Tourette Syndrome
Foods and drinks rich in tyramine: - CORRECT ANS ***cheese, wine, beer, cured/smoked meats
For depressed individuals with anorexia, increased appetite and weight gain, are possibly
beneficial side effects of this Atypical Antidepressant: - CORRECT ANS ***mirtazapine
Function of the Mesocortical pathway: - CORRECT ANS ***emotions
Function of the Tuberoinfundibular pathway: - CORRECT ANS ***releases Dopamine to limit the
secretion of Prolactin
, Functions of the Mesolimbic pathway: - CORRECT ANS ***motivation and desire
Functions of the Nigrostriatal pathway: - CORRECT ANS ***controls involuntary movements
and coordination (contains motor neurons)
All SSRIs but paroxetine (D) are pregnancy category - CORRECT ANS ***C
Another pathway of the CNS that is rich in Dopamine receptors and is responsible for eating
behavior: - CORRECT ANS ***Medullary Periventricular
Another region of the CNS that is rich in Dopamine receptors and is responsible for initiating
the
When stimulated Alpha 2 receptors inhibit the activity of the presynaptic neuron and decrease
the release of these two neurotransmitters: - CORRECT ANS ***Norepinephrine and Serotonin
When stimulated Alpha 2 receptors inhibit the activity of the presynaptic neuron and decrease
the release of these two neurotransmitters: - CORRECT ANS ***Norepinephrine and Serotonin
When tyramine is not broken down, it increases the release of this neurotransmitter, which
causes hypertensive crisis: - CORRECT ANS ***Norepinephrine
When uninhibited, these two enzymes are responsible for breaking down tyramine: - CORRECT
ANS ***MAO-A and MAO-B
Which type of Antipsychotics are preferred? Typical (first-generation) or Atypical (second
generation): - CORRECT ANS ***Atypical (second generation)
Which Typical Antipsychotics have a stronger sedating effect but less extrapyramidal side
effects? Low potency or High potency Typical Antipsychotics: - CORRECT ANS ***Low potency
vomiting reflex: - CORRECT ANS ***Chemoreceptor trigger zone
