NRNP 6566 Advanced Clinical Management – Advanced
Prac ce Registered Nurse (APRN) Curriculum –Ques on
Exam with Verified Ques ons and Answers
Ques on 1
A 54-year-old pa ent with type 2 diabetes has an A1C of 8.6% despite me ormin therapy.
Which is the most appropriate next step?
A. Discon nue me ormin and start insulin only
B. Add a second agent such as a GLP-1 receptor agonist
C. Stop all medica ons and focus on diet only
D. Start an bio cs for possible infec on
Correct Answer: B
Ra onale: When A1C remains above target despite me ormin, a second an hyperglycemic
agent (e.g., GLP-1 RA or SGLT2 inhibitor) is typically added.
Ques on 2
A pa ent presents with chest pain radia ng to the jaw, diaphoresis, and nausea. ECG shows
ST-eleva on in leads II, III, and aVF. What is the most likely diagnosis?
A. Anterior MI
B. Inferior STEMI
C. Pericardi s
D. Stable angina
Correct Answer: B
Ra onale: ST eleva on in II, III, aVF indicates an inferior myocardial infarc on (RCA territory).
,Ques on 3
Which lab finding is most consistent with chronic kidney disease?
A. Elevated GFR
B. Decreased crea nine
C. Elevated BUN and crea nine
D. Low potassium and low phosphate
Correct Answer: C
Ra onale: CKD is associated with decreased renal clearance leading to increased BUN and
crea nine.
Ques on 4
A pa ent presents with fever, produc ve cough, and right lower lobe consolida on on chest
x-ray. Most likely diagnosis?
A. Asthma exacerba on
B. COPD flare
C. Community-acquired pneumonia
D. Pulmonary embolism
Correct Answer: C
Ra onale: Fever + produc ve cough + lobar infiltrate = pneumonia.
Ques on 5
Which medica on is first-line for uncomplicated hypertension in a Black adult without
comorbidi es?
A. ACE inhibitor
B. Beta blocker
C. Thiazide diure c
D. Digoxin
Correct Answer: C
Ra onale: Thiazide diure cs or calcium channel blockers are first-line per guidelines.
, Ques on 6
A pa ent on warfarin has an INR of 6.2 with no bleeding. What is the best ac on?
A. Increase warfarin dose
B. Hold warfarin temporarily
C. Administer heparin
D. Give aspirin
Correct Answer: B
Ra onale: INR >5 without bleeding → hold warfarin and reassess.
Ques on 7
Which symptom is most consistent with hyperthyroidism?
A. Weight gain and fa gue
B. Bradycardia
C. Heat intolerance and tachycardia
D. Cold intolerance
Correct Answer: C
Ra onale: Hyperthyroidism increases metabolic ac vity.
Ques on 8
A 68-year-old pa ent has sudden unilateral facial droop sparing the forehead. What is the
most likely diagnosis?
A. Bell’s palsy
B. Ischemic stroke
C. Migraine
D. TIA only
Correct Answer: B
Ra onale: Forehead sparing indicates UMN lesion → stroke.
Ques on 9