BCHS 3304 Final Questions and CORRECT Answers
An enzyme cannot make a rxn thermodynamically favorable
True
Phase 2 clinical trails are focused on evaluating the safety of new drug candidates
False
In the rxn coordinate graph showing below, which location(s) is (are) intermediate states?
None of the above (C&E)
In the presence of a competitive inhibitor at [I] = 3 mM, the apparent Km is three times the
KM for the uninhibited rxn. What is K1?
1.5 mM
The role of water in the lysozyme active site is to
Regenerate the active form of the catalytic residues at the active site
A first order rxn has a t1/2 of 20 mins. What is the reaction rate constant k?
0.0035 min-1
In a serine protease enzyme, the catalytic triad drawing in the order of the "proton shuttle
network" is
Ser-His-Asp
For the elementary rxn A + B ->P, the correct rate equation and reaction order are
v=kAB, it is a second order rxn
, Which of the following types of inhibition does the figure below reflect?
Uncompetitive
Which of the following is not true about enzymes?
Enzymes catalyze rxns in the forward direction only
The length of an alpha helix of 20 AA residues is
30 A
Which residue in the seven-residue repeat (abcdefg) of the alpha-keratin helical wheel
provide a hydrophobic interaction to associate two coiled coils?
a, d
The GFP structure is shown below. The major motif in this protein is
beta sheets
The following figure showed the binding curves of myoglobin, stripped hemoglobin, adult
hemoglobin in whole blood at conditions of (normal, elevated CO2, elevated area). Curve a
is hyperbolic and the others are sigmoidal. The binding curve in whole blood is d. The
binding curves for myoglobin, whole blood w/ elevated CO2, and whole blood in elevated
area are:
a-e-f
The mis-folding of Amyloid-beta protein leads to
Alzheimer's disease
An enzyme cannot make a rxn thermodynamically favorable
True
Phase 2 clinical trails are focused on evaluating the safety of new drug candidates
False
In the rxn coordinate graph showing below, which location(s) is (are) intermediate states?
None of the above (C&E)
In the presence of a competitive inhibitor at [I] = 3 mM, the apparent Km is three times the
KM for the uninhibited rxn. What is K1?
1.5 mM
The role of water in the lysozyme active site is to
Regenerate the active form of the catalytic residues at the active site
A first order rxn has a t1/2 of 20 mins. What is the reaction rate constant k?
0.0035 min-1
In a serine protease enzyme, the catalytic triad drawing in the order of the "proton shuttle
network" is
Ser-His-Asp
For the elementary rxn A + B ->P, the correct rate equation and reaction order are
v=kAB, it is a second order rxn
, Which of the following types of inhibition does the figure below reflect?
Uncompetitive
Which of the following is not true about enzymes?
Enzymes catalyze rxns in the forward direction only
The length of an alpha helix of 20 AA residues is
30 A
Which residue in the seven-residue repeat (abcdefg) of the alpha-keratin helical wheel
provide a hydrophobic interaction to associate two coiled coils?
a, d
The GFP structure is shown below. The major motif in this protein is
beta sheets
The following figure showed the binding curves of myoglobin, stripped hemoglobin, adult
hemoglobin in whole blood at conditions of (normal, elevated CO2, elevated area). Curve a
is hyperbolic and the others are sigmoidal. The binding curve in whole blood is d. The
binding curves for myoglobin, whole blood w/ elevated CO2, and whole blood in elevated
area are:
a-e-f
The mis-folding of Amyloid-beta protein leads to
Alzheimer's disease
