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NCLEX Respiratory Neuro GI Cardio Endocrine Integumentary Complete Systems Review Questions and Answers 2025/ 2026 100% Verified Comprehensive Medical-Surgical Nursing and NCLEX Preparation Solution Guide

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Access a fully updated 2025/ 2026 NCLEX systems-based review covering respiratory, neurological, gastrointestinal, cardiovascular, endocrine, and integumentary nursing concepts. This with solution guide provides structured practice questions, detailed rationales, and comprehensive clinical review designed to strengthen critical thinking and nursing judgment. Improve understanding of pathophysiology, patient assessment, prioritization, pharmacology, and evidence-based nursing interventions across major body systems while building confidence for NCLEX success through organized, verified practice materials.

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Institution
Nursing Rn
Course
Nursing rn

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NCLEX: Respiratory, Neuro, GI, Ortho
Cardio GI, Endocrine,
Integumentary


Integumentary NCLEX

A client with dermatitis has been prescribed a topical corticosteroid for use on the
affected areas, and the nurse has reinforced instructions about the use of this
medication. Which statement by the client indicates a need for further teaching?
I will apply a bandage over the site after applying the medication.

Collagenase (Santyl) is prescribed for a client with a severe burn to the hand. The
nurse provides instructions to the client regarding the use of the medication.
Which statement by the client indicates an accurate understanding of the use of
this medication?
I will apply the ointment once a day and cover it with a sterile dressing.

Isotretinoin (Amnesteem, Clavaris) is prescribed for a client with severe
acne. Before the administration of this medication, the nurse anticipates that
which laboratory test will be prescribed?
Triglyceride level

A client is newly admitted to the hospital with cellulitis of the lower leg. The
nurse checks the health care provider's prescription sheet to see if which
therapy has been prescribed for site care?
Warm compresses

A client with eczema has a prescription for a topical corticosteroid. The nurse
cautions the client to use the product carefully in which area where the risk of
systemic absorption is greater?
Face

The nurse is providing instructions to a client with a diagnosis of scabies
regarding the administration of crotamiton (Eurax). Which statement by
the client indicates an understanding regarding the application of this
medication?
"I will massage the medication into the skin from my chin downward and apply a second
application in 24 hours, followed by a cleansing bath 48 hours after the second application."



The health care provider has prescribed silver sulfadiazine (Silvadene) for the
client with a partial-thickness burn, which has cultured positive for gram-negative
bacteria. The nurse is reinforcing information to the client about the medication.
Which statement made by the client indicates a lack of understanding about the
treatments?
"The medication will permanently stain my skin."

,A client is seen in the clinic for complaints of skin itchiness that has been
persistent over the past several weeks. Following data collection, it has been
determined that the client has scabies. Lindane is prescribed, and the nurse is
asked to provide instructions to the client regarding the use of the medication.
How should the nurse teach the client to apply the cream?
Leave the cream on for 8 to 12 hours and then remove by washing.

The nurse is applying a topical glucocorticoid on a client with eczema. The nurse
monitors for systemic absorption of the medication if the medication is being
applied to which body areas?
Axilla


Coal tar has been prescribed for a client with a diagnosis of psoriasis, and the
nurse reinforces instructions to the client about the medication. Which statement
by the client indicates a need for further teaching?
This medication can cause systemic effects.

Isotretinoin (Accutane) is prescribed for a client to treat severe cystic acne. The
nurse tells the client that the length of the usual prescribed course of treatment
is which?

15 to 20 weeks


Mafenide acetate (Sulfamylon) is prescribed for the client with a burn injury.
When applying the medication, the client complains of local discomfort and
burning. Which is the most appropriate nursing action?
Informing the client this is normal.

The burn client is receiving treatments of topical mafenide acetate (Sulfamylon)
to the site of injury. The nurse monitors the client knowing that which indicates a
systemic effect has occurred?

Hyperventilation

Collagenase (Santyl) is prescribed for a client with a severe burn to the hand. The
nurse is preparing to reinforce instructions to the client and spouse regarding
the wound treatment. Which directions should the nurse include in the
instructions?

Apply once a day and cover the wound with a sterile dressing.




The nurse is assigned to care for a client with a leg ulcer. Sutilains (Travase)
treatments are prescribed. The nurse should avoid which action when performing
the treatment?

Covering the sutilains application with a dry sterile dressing

,A client is undergoing radiation therapy to treat lung cancer. Following the
treatment, the nurse notes that the chest and neck are red, and the client is
complaining of pain at the radiation site. How should the nurse interpret this
data?
A superficial injury to tissue from the radiation.

A client with severe acne is seen in the clinic, and the health care provider (HCP)
prescribes isotretinoin (Amnesteem, Clavaris). The nurse reviews the client's
medication record and should contact the HCP if the client is taking which
medication?

Vitamin A
The nurse is applying a topical corticosteroid to a client with eczema. The nurse
should monitor for the potential for increased systemic absorption of the
medication if the medication is being applied to which body area?
Axilla



A client with a burn injury is applying mafenide acetate (Sulfamylon) to the
wound. The client calls the health care provider's office and tells the nurse that
the medication is uncomfortable and is causing a burning sensation. Which
instructions should the nurse reinforce to the client?

Continue with the treatment because this is expected.

The nurse reinforces instructions to a client regarding the use of tretinoin (Retin-
A). Which statement by the client indicates the need for further teaching?



I should apply a very thin layer to my skin.

The nurse is caring for a client with a burn injury to the lower legs. Silver
sulfadiazine (Silvadene) is prescribed to be applied to the sites of injury. Which
indicates the appropriate method to apply this medication?
Apply to cleansed, debrided wounds as prescribed.


The nurse is caring for a client diagnosed with scabies who has just been
prescribed crotamiton (Eurax). The nurse provides which instruction for
application of this medication?
Massage the medication into the skin from the chin downward, and apply a second
application in 24 hours, followed up with a cleansing bath 48 hours after the second
application.

Salicylic acid is prescribed for a client with a diagnosis of psoriasis.
The nurse monitors the client, knowing that which finding indicates the
presence of systemic toxicity from this medication?

, Tinnitus

The nurse reviews the laboratory results for a client diagnosed with leukemia
who is receiving chemotherapy. The nurse notes that the white blood cell (WBC)
count is 2000 cells/mm3. The nurse identifies the finding as indicative of which?
Signifying leukopenia

The nurse in a health care provider's office has scheduled a client with
dermatitis to be seen in 1 week for a patch test. The nurse should reinforce
instructions to the client to do which action before the procedure?
Discontinue the prescribed antihistamine 2 days before the test.

The clinic nurse is collecting data on a client being admitted. The nurse notes
that the client is taking azelaic acid (Azelex). Because of the medication
prescription the nurse should suspect that the client is being treated for which
condition?
Acne



1. An adult client was burned as a result of an explosion. The burn initially
affected the client's entire face (the anterior half of the head) and the
upper half of the anterior torso, and there were circumferential burns to
the lower half of both of the arms. The client's clothes caught on fire, and
the client ran, which caused subsequent burn injuries of the posterior
surface of the head and the upper half of the posterior torso. According
to the rule of nines, what is the extent of this client's burn injury? Fill in
the blank.
a. 36%
2. A client returns to the clinic for follow-up treatment after a skin biopsy of
a suspicious lesion that was performed 1 week ago. The biopsy report
indicates that the lesion is a melanoma. The nurse understands that
which describes a characteristic of this type of a lesion?
a. It is highly metastatic.
3. The nurse is reviewing the health care record of a client with a lesion
that has been diagnosed as malignant melanoma. The nurse should
expect which characteristic of this type of lesion to be documented in
the client's record?
a. An irregularly shaped lesion
4. The nurse reinforces instructions to a group of clients regarding
measures that will assist with the prevention of skin cancer. Which
statement by a client indicates the need for further teaching?
a. "I need to avoid sun exposure before 10:00 AM and after 4:00 AM."
5. A client arrives at the emergency department and has experienced
frostbite to the right hand. Which should the nurse expect to find when
inspecting the client's hand?
a. A white color of the skin, which is insensitive to touch
6. The evening nurse reviews the nursing documentation in the client's chart
and notes that the day nurse has documented that the client has a stage
2 pressure ulcer in the sacral area. Which should the nurse expect to find
when checking the client's sacral area?
a. Partial-thickness skin loss of the epidermis

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Institution
Nursing rn
Course
Nursing rn

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Uploaded on
June 27, 2026
Number of pages
256
Written in
2025/2026
Type
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Contains
Questions & answers

Subjects

  • nclex systems review
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