Complete 200-Question Test Bank with NGN Case
Scenarios & Detailed Rationales
Wilkes University | 2026/2027 Edition | 100% Pass
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COMPREHENSIVE EXAM
Topic Area
Neurobiology & Neurotransmission
Pharmacokinetics & Pharmacodynamics
Antidepressants (SSRIs, SNRIs, TCAs, MAOIs,
Atypicals)
Antipsychotics (Typical & Atypical)
Mood Stabilizers & Anticonvulsants
Anxiolytics, Sedatives & Hypnotics
Substance Use Disorders – Opioids & Alcohol
,Topic Area
Substance Use Disorders – Stimulants,
Nicotine, Others
ADHD & Neurodevelopmental Disorders
Dementia & Geriatric Psychopharmacology
Personality Disorders & Evidence-Based
Therapies
NGN Case Scenarios (Integrated)
SECTION 1: NEUROBIOLOGY & NEUROTRANSMISSION
(Questions 1–15)
1. A nursing student asks the preceptor to explain the
primary difference between pharmacokinetics and
pharmacodynamics. Which response is most accurate?
A) "Pharmacokinetics is the effect of the drug on the
body; pharmacodynamics is what the body does to the
drug."
, B) "Pharmacokinetics is what the body does to the drug;
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pharmacodynamics is the effect of the drug on the body."
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C) "Pharmacokinetics involves receptor binding;
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pharmacodynamics involves drug absorption."
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D) "There is no significant difference between the two
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terms."
K
Answer: B) "Pharmacokinetics is what the body does to the
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drug; pharmacodynamics is the effect of the drug on the
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body."
K
Rationale: Pharmacokinetics describes what the body does
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to the drug (Absorption, Distribution, Metabolism,
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Excretion – ADME). Pharmacodynamics describes what the
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drug does to the body (receptor binding, mechanism of
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action, clinical effect).
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2. Which neurotransmitter is the primary inhibitory
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neurotransmitter in the central nervous system?
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A) Glutamate
K
B) Dopamine
K
C) GABA
K
D) Norepinephrine
K
Answer: C) GABA K K
Rationale: GABA (gamma-aminobutyric acid) is the
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