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NURS 5334 Exam 3 Study Guide | Advanced Pharmacology Questions & Answers

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Master NURS 5334 Exam 3 with this comprehensive study guide. Includes detailed answers on diabetes, thyroid disorders, respiratory medications, and more for advanced nursing pharmacology.

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NURS 5334 EXAM 3 QUIZZES AND ANSWERS
VERIFIED CORRECTLY
1. What drugs are used to treat gestational diabetes?

Metformin and Insulin



2. What A1C value indicates diabetes mellitus? Pre-DM?

6.5% or greater is considered

diabetes 5.7-6.4% pre-diabetes



3. What fasting and random values indicate DM?

Fasting plasma glucose—126 or greater is diabetes

Random (casual) plasma glucose—anything greater than 200 is diabetes



4. What are complications of insulin therapy?

Hypoglycemia

Can develop lipohypertrophy

 Accumulation of subcutaneous fat that occurs when it is injected too
frequently at the same site

Allergic reactions

 Characterized by red and intensely itchy welts, breathing becomes
difficult
 If severe allergy develops:

-Desensitization procedure (small doses to larger

doses) Hypokalemia

 Promotes the uptake of potassium cells and insulin activates a
membrane-bound enzyme with sodium potassium and ATPase that
pumps potassium into the cells and sodium out

,NURS 5334 EXAM 3 QUIZZES AND ANSWERS
VERIFIED CORRECTLY

5.Drug interactions?

Hypoglycemic agents

 Can intensify the hypoglycemia included by insulin
 Examples: sulfonylureas, glinides,

alcohol Use with caution with

hyperglycemic agents

 Examples: thiazide and glucocorticoids and sympathomimetics



6. What effect do beta blockers have on insulin?
 delay awareness of and response to hypoglycemia by masking the
signs that are associated with stimulation of sympathetic nervous
system
 Impair glycogenolysis
 Prevent the bodies counter-regulatory response



7.What are other therapeutic uses besides DM?

 Hyperkalemia
 Aids in diagnosis of GH deficiency
 Diabetic ketoacidosis



8.Insulin dosage must be coordinated with what?

Carbohydrate intake



9.What is B/P goal in diabetic?

To be controlled, within normal 120/80



10. What medication can be given to decrease risk of diabetic nephropathy?

ACE inhibitor or ARB

,NURS 5334 EXAM 3 QUIZZES AND ANSWERS
VERIFIED CORRECTLY
11. What role does exercise play in treatment of both type 1 and type 2 DM?

 Exercise increases cellular responsiveness to insulin and increases
glucose tolerance
 150 minute per week of moderate intensity exercise is recommended



12. What are the 4 steps in the 4-step approach?

Step 1—diagnosis

 Lifestyle changes plus

metformin Step 2

 Lifestyle changes plus metformin and a second drug (sulfonylurea,
TZD or a DPP4 inhibitor, a sodium glucose cotransporter or SGLT-2
inhibitor, a glucagon- like peptide 1, or a GLP-1 receptor agonist or
basal insulin
 Second drug choice made considering efficacy, the hypoglycemia
risk of the patient, the patient tolerability, and weight-related
considerations (some help weight loss, some cause weight gain),
cost

Step 3

 Three drug combination
 Metformin
 Plus 2 other drugs from step 2

Decided based on a drug and patient specific

considerations Step 4

 If 3 drug combination that includes basal insulin fails after 3-6
months, more complex insulin regimen
 Usually in combination with one or more non-insulin medications



13. When a patient is on insulin therapy what are the blood glucose goals
before meals? At bedtime?

 Before meals—70-130
 Bedtime—100-140

, NURS 5334 EXAM 3 QUIZZES AND ANSWERS
VERIFIED CORRECTLY
14. What is the A1C goal? When is goal below 7 not appropriate?

 7% or below
 Those with severe hypoglycemia risk, limited life expectancy,
advanced micro vascular or macro vascular complications—not
below 7



15. What are the short acting insulins? Intermediate? Long acting?

Short duration: Rapid acting

 Insulin lispro [Humalog]
 Insulin aspart [NovoLog]
 Insulin glulisine

[Apidra] Short duration:

Slower acting

 Regular insulin [Humulin R,

Novolin R] Intermediate duration

 Neutral protamine Hagedorn (NPH) insulin
 Insulin detemir

[Levemir] Long duration

 Insulin glargine



16. When are short duration insulins used?

 Administered in association with meals to control the post-prandial
rise in blood glucose between meals and at night



17. When are intermediate insulins needed?

 Administer 2-3 times daily to provide glycemic control between meals
and during the night



18. How long is duration of glargine? Levemir? Degludec?

 Glargine—up to 24 hours

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