PHARMACEUTICAL CHEMISTRY EXAMINATION QUESTIONS AND CORRECT ANSWER WITH EXPLANATION GRADED A+ STUDY GUIDE

PHARMACEUTICAL CHEMISTRY EXAMINATION
QUESTIONS AND CORRECT ANSWER WITH
EXPLANATION GRADED A+ STUDY GUIDE SOUTHERN
NEW HAMPSHIRE UNIVERSITY
1. Pharmaceutical chemistry is the study of:
A. Drugs and their chemical properties
B. Rocks and minerals
C. Weather systems
D. Plant ecology only
Answer: A
Rationale: It focuses on drug design and chemistry.

2. A drug is defined as a substance that:
A. Diagnoses, treats, or prevents disease
B. Only colors solutions
C. Only increases weight
D. Only produces heat
Answer: A
Rationale: Drugs have therapeutic effects.

3. Pharmacology is closely related to:
A. Pharmaceutical chemistry
B. Geology
C. Astronomy
D. Meteorology
Answer: A
Rationale: Both deal with drugs and biological effects.

4. Active pharmaceutical ingredient (API) is:
A. The main drug component
B. A filler only
C. A coating only
D. A dye only
Answer: A
Rationale: Responsible for therapeutic effect.

,5. Excipients are:
A. Inactive drug components
B. Active drugs
C. Toxic substances only
D. Catalysts only
Answer: A
Rationale: Help formulation stability.

6. Pharmacodynamics is the study of:
A. Drug effects on the body
B. Drug manufacturing only
C. Drug packaging only
D. Drug storage only
Answer: A
Rationale: Drug action mechanisms.

7. Pharmacokinetics is the study of:
A. ADME processes
B. Drug colors
C. Drug shapes
D. Drug taste only
Answer: A
Rationale: Absorption, distribution, metabolism, excretion.

8. ADME stands for:
A. Absorption, Distribution, Metabolism, Excretion
B. Action, Dose, Medicine, Effect
C. Acid, Drug, Molecule, Enzyme
D. None
Answer: A
Rationale: Drug movement in body.

9. Absorption is:
A. Entry of drug into bloodstream
B. Drug breakdown
C. Drug removal
D. Drug synthesis
Answer: A
Rationale: First step in ADME.

, 10. Distribution is:
A. Movement of drug in body fluids
B. Drug synthesis
C. Drug excretion
D. Drug packaging
Answer: A
Rationale: Transport process.

11. Metabolism of drugs mainly occurs in:
A. Liver
B. Heart
C. Lungs
D. Bones
Answer: A
Rationale: Liver enzymes process drugs.

12. Excretion is removal of drugs via:
A. Urine or feces
B. Skin only
C. Hair only
D. Bones
Answer: A
Rationale: Elimination pathways.

13. First-pass metabolism occurs in:
A. Liver
B. Brain
C. Heart
D. Skin
Answer: A
Rationale: Drug breakdown before circulation.

14. Bioavailability refers to:
A. Amount of drug reaching circulation
B. Drug color
C. Drug shape
D. Drug taste
Answer: A
Rationale: Fraction of active drug absorbed.