Lehne's Pharmacology for Nursing
Care
12th Edition
• Author(s)Jacqueline Rosenjack
Burchum; Laura D. Rosenthal
,TEST BANK
Question 1 (MCQ)
Clinical Scenario
A newly licensed nurse asks why two patients receiving the
same dose of an oral antihypertensive medication experience
different therapeutic responses. The charge nurse explains that
several patient-specific factors influence drug action.
Question Stem
Which factor best explains why patients may respond
differently to the same medication dose?
Answer Options
A. Drug responses are identical when standard doses are
prescribed.
B. Individual differences in age, organ function, genetics,
disease states, and concurrent medications influence drug
response.
C. The color and shape of a medication determine its
therapeutic effect.
D. Drug effectiveness depends only on the manufacturer's
formulation.
,Correct Answer
B
Detailed Rationale
Drug therapy is individualized because patients differ in
pharmacokinetic and pharmacodynamic characteristics. Age-
related physiological changes, hepatic and renal function,
genetic variations, disease processes, nutrition, and drug
interactions all influence absorption, distribution, metabolism,
excretion, and receptor sensitivity. Safe nursing practice
requires ongoing assessment rather than assuming all patients
will respond similarly to standard doses.
Incorrect Option Analysis
A
Why Incorrect
Drug responses vary considerably among individuals.
Common Misconception
Standard dosing guarantees identical outcomes.
Medication Safety Risk
, May lead to inadequate monitoring or delayed recognition of
toxicity.
Nursing Consideration
Assess therapeutic response and adverse effects individually.
C
Why Incorrect
Medication appearance does not determine pharmacologic
activity.
Common Misconception
Visual characteristics indicate drug potency.
Medication Safety Risk
May encourage unsafe assumptions when verifying
medications.
Nursing Consideration
Use medication labels and verification systems.
D
Why Incorrect
Care
12th Edition
• Author(s)Jacqueline Rosenjack
Burchum; Laura D. Rosenthal
,TEST BANK
Question 1 (MCQ)
Clinical Scenario
A newly licensed nurse asks why two patients receiving the
same dose of an oral antihypertensive medication experience
different therapeutic responses. The charge nurse explains that
several patient-specific factors influence drug action.
Question Stem
Which factor best explains why patients may respond
differently to the same medication dose?
Answer Options
A. Drug responses are identical when standard doses are
prescribed.
B. Individual differences in age, organ function, genetics,
disease states, and concurrent medications influence drug
response.
C. The color and shape of a medication determine its
therapeutic effect.
D. Drug effectiveness depends only on the manufacturer's
formulation.
,Correct Answer
B
Detailed Rationale
Drug therapy is individualized because patients differ in
pharmacokinetic and pharmacodynamic characteristics. Age-
related physiological changes, hepatic and renal function,
genetic variations, disease processes, nutrition, and drug
interactions all influence absorption, distribution, metabolism,
excretion, and receptor sensitivity. Safe nursing practice
requires ongoing assessment rather than assuming all patients
will respond similarly to standard doses.
Incorrect Option Analysis
A
Why Incorrect
Drug responses vary considerably among individuals.
Common Misconception
Standard dosing guarantees identical outcomes.
Medication Safety Risk
, May lead to inadequate monitoring or delayed recognition of
toxicity.
Nursing Consideration
Assess therapeutic response and adverse effects individually.
C
Why Incorrect
Medication appearance does not determine pharmacologic
activity.
Common Misconception
Visual characteristics indicate drug potency.
Medication Safety Risk
May encourage unsafe assumptions when verifying
medications.
Nursing Consideration
Use medication labels and verification systems.
D
Why Incorrect
