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, Prophecy RN Pharmacology A Exam Questions and
Answers with Detailed Rationales | Prophecy
Assessment Test Prep | Latest Updated Study Guide
2026/2027 | Verified Answers | Graded A+
Question 1
Which of the following medications is known to cause orange-colored
urine?
• A) Phenazopyridine (Pyridium) ✓
• B) Rifampin
• C) Nitrofurantoin
• D) Metronidazole
Answer: A) Phenazopyridine (Pyridium)
Rationale: Phenazopyridine is a urinary tract analgesic that is excreted
unchanged in the urine and imparts a characteristic orange-red color. This
is a harmless but expected side effect and patients should be warned about
it to prevent alarm. Rifampin can also cause orange/red discoloration of
urine, tears, and sweat, but phenazopyridine is most classically associated
with this effect. Nitrofurantoin may cause brown discoloration, and
metronidazole can darken urine.
Question 2
You are ordered to give digoxin. Your patient's vital signs are as
follows: Blood Pressure 130/75, Temp 97.9 oral, HR 52, O2 Sat 100%
room air. What should you do next?
• A) Administer digoxin as ordered
, • B) Hold digoxin and call the provider ✓
• C) Administer digoxin and monitor heart rate
• D) Administer atropine first
Answer: B) Hold digoxin and call the provider
Rationale: The patient's heart rate is 52 bpm, which is bradycardic. Digoxin
has a narrow therapeutic index and slows the heart rate by increasing vagal
tone and decreasing AV node conduction. The general rule for digoxin
administration is to hold the dose if the apical pulse is below 60 bpm (or
according to facility policy, typically <60) and notify the healthcare
provider. Administering digoxin to a bradycardic patient could precipitate
symptomatic bradycardia, heart block, or cardiac arrest. The blood pressure
is adequate, but the heart rate is the primary concern here.
Question 3
Normal Saline (NS) is the solution of choice over D5W when preparing
to administer a blood transfusion because:
• A) Normal Saline is an isotonic solution and prevents cell hemolysis ✓
• B) D5W can cause hyperglycemia
• C) Normal Saline is less expensive
• D) D5W can cause clot formation
Answer: A) Normal Saline is an isotonic solution and prevents cell
hemolysis
Rationale: Normal saline (0.9% NaCl) is the only solution compatible with
blood products for transfusion. It is isotonic and maintains the integrity of
red blood cells, preventing hemolysis. D5W (dextrose 5% in water) is
hypotonic and can cause red blood cell swelling and hemolysis.
Additionally, D5W can cause agglutination of red blood cells. Dextrose