Chapter 01: Introduction to Pathophysiology
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Test Bank
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MULTIPLE CHOICE L
1. Which of the following would be the most likely cause of an iatrogenic disease?
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a. An inherited disorderL L
b. A combination of specific etiological factors
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c. An unwanted effect of a prescribed drug
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d. Prolonged exposure to toxic chemicals in the environment L L L L L L L
ANS: C L REF: 6 L
2. The manifestations of a disease are best defined as the:
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a. subjective feelings of discomfort during a chronic illness. L L L L L L L
b. signs and symptoms of a disease. L L L L L
c. factors that precipitate an acute episode of a chronic illness.
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d. early indicators of the prodromal stage of infection.
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ANS: B L REF: 6 L
3. The best definition of the term prognosis is the:
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a. precipitating factors causing an acute episode. L L L L L
b. number of remissions to be expected during the course of a chronic illness.
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c. predicted outcome or likelihood of recovery from a specific disease.
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d. exacerbations occurring during chronic illness. L L L L
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ANS: C L REF: 7 L
4. Which of the following is considered a systemic sign of disease?
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a. Swelling of the knee L L L
b. Fever
c. Pain in the neck L L L
d. Red rash on the face L L L L
ANS: B L REF: 6 L
5. Etiology is defined as the study of the:
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a. causes of a disease. L L L
b. course of a disease. L L L
c. expected complications of a disease. L L L L
d. manifestations of a disease. L L L
ANS: A L REF: 5 L
6. A type of cellular adaptation in which there is a decrease in cell size is referred to as:
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a. hypertrophy.
b. metaplasia.
c. anaplasia.
d. atrophy.
ANS: D L REF: 8 L
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7. A change in a tissue marked by cells that vary in size and shape and show increased mitotic
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figures would be called:
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a. metaplasia.
b. atrophy.
c. dysplasia.
d. hypertrophy.
ANS: C L REF: 8 L
8. A deficit of oxygen in the cells usually due to respiratory or circulatory problems is called:
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a. apoptosis.
b. ischemia.
c. hypertrophy.
d. necrosis.
ANS: B L REF: 9 L
9. When a group of cells in the body dies, the change is called:
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a. ischemia.
b. gangrene.
c. hypoxia.
d. necrosis.
ANS: D L REF: 10 L
10. Rigorous weight lifting/body building regimens may result in the skeletal muscle cells
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a. hypertrophy.
b. dysplasia.
c. atrophy.
d. regeneration.
ANS: A L REF: 8 LLL
11. The term cancer refers to:
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a. dysplasia.
b. hyperplasia.
c. metaplasia.
d. malignant neoplasm. L
ANS: D L REF: 9 LLL
12. To which of the following does the term apoptosis refer?
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a. Increased rate of mitosis by certain cells L L L L L L
b. Ischemic damage to cells L L L
c. Liquefaction of necrotic tissue L L L
d. Preprogrammed cell self-destruction L L
ANS: D L REF: 9 L
13. Which of the following statements is TRUE?
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a. Alteration of DNA does not change cell function. L L L L L L L
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b. Damaged cells may be able to repair themselves. L L L L L L L
c. All types of cells die at the same rate.
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d. Mild ischemia causes immediate cell death.
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ANS: B L REF: 10 L
14. Caseation necrosis refers to an area where:
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a. cell proteins have been denatured.
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b. cell are liquefied by enzymes.
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c. dead cells form a thick cheesy substance.
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d. bacterial invasion has occurred. L L L
ANS: C L REF: 10 L
15. Routine application of sun block to skin would be an example of:
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a. an iatrogenic cause of cancer.
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b. a preventive measure.
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c. a precipitating factor.
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d. a predisposing condition.
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ANS: B L REF: 6 L
16. A circumstance that causes a sudden acute episode of a chronic disease to occur is termed:
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a. latent stage. L
b. predisposing factor. L
c. incidence.
d. precipitating factor. L
ANS: D L REF: 7 L
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17. The term homeostasis refers to:
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a. the causative factors in a particular disease.
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b. maintenance of a stable internal environment. L L L L L
c. a condition that triggers an acute episode.
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d. a collection of signs and symptoms.
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ANS: B L REF: 2 L
18. Which term is used to describe a new and secondary or additional problem that arises after the
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original disease has been established?
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a. Symptoms
b. Occurrence
c. Manifestations
d. Complication
ANS: D L REF: 7 L
19. Pathophysiology involves the study of: L L L L
a. the structure of the human body.
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b. the functions of various organs in the body.
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c. functional or structural changes resulting from disease processes.
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d. various cell structures and related functions.
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ANS: C L REF: 2 L
20. Which of the following is the best definition of epidemiology?
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a. The science of tracking the occurrence and distribution of diseases
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b. The relative number of deaths resulting from a particular disease
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c. Identification of a specific disease through evaluation of signs and symptoms L L L L L L L L L L
d. The global search for emerging diseases
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ANS: A L REF: 7 L
21. Which of the following can cause cell injury or death?
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1. Hypoxia
2. Exposure to excessive cold L L L
3. Excessive pressure on a tissue L L L L
4. Chemical toxins L
a. 1, 2 L
b. 2, 4
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c. 1, 3, 4 L L
d. 1, 2, 3, 4
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ANS: D L REF: 9 L
22. All of the following are part of the Seven Steps to Health EXCEPT:
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a. follow cancer screening guidelines. L L L
b. use sun block agents whenever exposed.
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c. participate in strenuous exercise on a regular daily basis. L L L L L L L L
d. choose high fiber, lower fat foods. L L L L L
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ANS: C L REF: 2 L
23. The term disease refers to:
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a. the period of recovery and return to a normal healthy state.
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b. a deviation from the normal state of health and function.
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c. the treatment measures used to promote recovery.
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d. a basic collection of signs and symptoms.
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ANS: B L REF: 2 L
24. A collection of signs and symptoms, often affecting more than one organ or system, that
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usually occur together in response to a certain condition is referred to as a (an):
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a. acute disease. L
b. multiorgan disorder. L
c. syndrome.
d. manifestation.
ANS: C L REF: 7 L
25. All of the following statements are correct about cell damage EXCEPT:
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a. The initial stage of cell damage often causes an alteration in metabolic reactions.
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b. If the factor causing the damage is removed quickly, the cell may be able to
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recover and return to its normal state. L L L L L L
c. If the noxious factor remains for an extended period of time, the damage becomes
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