NURS 5334 ADVANCED PHARMACOLOGY QUIZ 1 | 50 QUESTIONS
AND ANSWERS | 2026 UPDATE | 100% CORRECT - UTA.
Mechanism of action (MOA) of bisphosphonates - (ANSWER)Inhibit osteoclast-mediated bone resorption
by binding to hydroxyapatite in bone.
IV bisphosphonates - (ANSWER)Should be given to a patient with GERD (avoid PO due to esophageal
irritation).
Four components of a prescription - (ANSWER)Superscription, Inscription, Subscription, Signa (directions
to patient).
Drugs that can cause bone loss - (ANSWER)Glucocorticoids, phenytoin, aromatase inhibitors, heparin,
and long-term PPIs.
Conditions treated with bisphosphonates - (ANSWER)Osteoporosis and Paget's disease.
T-score and Z-score in a DEXA scan - (ANSWER)T-score: compares to young adult; Z-score: compares to
age-matched controls.
Vitamin D3 prescription - (ANSWER)For osteomalacia (soft bones due to vitamin D deficiency).
Lidocaine eye drops - (ANSWER)Used for numbing the eye for exams or procedures—short-term use
only.
Eye makeup during an eye infection - (ANSWER)Discard all makeup to prevent reinfection.
Drug to avoid if tympanic membrane is ruptured - (ANSWER)Ciprofloxacin (due to ototoxicity risk).
Prevention of swimmer's ear - (ANSWER)Isopropyl alcohol or acetic acid drops to dry the ear canal.
, NURS 5334 ADVANCED PHARMACOLOGY QUIZ 1 | 50 QUESTIONS
AND ANSWERS | 2026 UPDATE | 100% CORRECT - UTA.
Debrox - (ANSWER)Used to soften and remove excessive ear wax (contains carbamide peroxide).
Prescribing medications to a friend - (ANSWER)Not recommended—must maintain formal provider-
patient relationship.
Prescription to prevent substitution with generic - (ANSWER)"Brand Medically Necessary."
Upregulation and downregulation - (ANSWER)Upregulation: increase in receptors due to low
stimulation; Downregulation: decrease in receptors due to high stimulation.
Bioavailability - (ANSWER)The percentage of a drug that reaches systemic circulation in active form.
MIC - (ANSWER)Minimum Inhibitory Concentration—the lowest drug concentration to inhibit bacterial
growth.
Lower drug doses for thin/malnourished patients - (ANSWER)They have less protein for binding and
increased drug sensitivity.
CYP450 inducer - (ANSWER)A drug that increases enzyme activity and speeds up metabolism (e.g.,
rifampin, phenytoin).
Dosing interval - (ANSWER)Based on the drug's half-life (T½).
Loading dose - (ANSWER)Used to quickly reach therapeutic levels for drugs with long half-lives.
AND ANSWERS | 2026 UPDATE | 100% CORRECT - UTA.
Mechanism of action (MOA) of bisphosphonates - (ANSWER)Inhibit osteoclast-mediated bone resorption
by binding to hydroxyapatite in bone.
IV bisphosphonates - (ANSWER)Should be given to a patient with GERD (avoid PO due to esophageal
irritation).
Four components of a prescription - (ANSWER)Superscription, Inscription, Subscription, Signa (directions
to patient).
Drugs that can cause bone loss - (ANSWER)Glucocorticoids, phenytoin, aromatase inhibitors, heparin,
and long-term PPIs.
Conditions treated with bisphosphonates - (ANSWER)Osteoporosis and Paget's disease.
T-score and Z-score in a DEXA scan - (ANSWER)T-score: compares to young adult; Z-score: compares to
age-matched controls.
Vitamin D3 prescription - (ANSWER)For osteomalacia (soft bones due to vitamin D deficiency).
Lidocaine eye drops - (ANSWER)Used for numbing the eye for exams or procedures—short-term use
only.
Eye makeup during an eye infection - (ANSWER)Discard all makeup to prevent reinfection.
Drug to avoid if tympanic membrane is ruptured - (ANSWER)Ciprofloxacin (due to ototoxicity risk).
Prevention of swimmer's ear - (ANSWER)Isopropyl alcohol or acetic acid drops to dry the ear canal.
, NURS 5334 ADVANCED PHARMACOLOGY QUIZ 1 | 50 QUESTIONS
AND ANSWERS | 2026 UPDATE | 100% CORRECT - UTA.
Debrox - (ANSWER)Used to soften and remove excessive ear wax (contains carbamide peroxide).
Prescribing medications to a friend - (ANSWER)Not recommended—must maintain formal provider-
patient relationship.
Prescription to prevent substitution with generic - (ANSWER)"Brand Medically Necessary."
Upregulation and downregulation - (ANSWER)Upregulation: increase in receptors due to low
stimulation; Downregulation: decrease in receptors due to high stimulation.
Bioavailability - (ANSWER)The percentage of a drug that reaches systemic circulation in active form.
MIC - (ANSWER)Minimum Inhibitory Concentration—the lowest drug concentration to inhibit bacterial
growth.
Lower drug doses for thin/malnourished patients - (ANSWER)They have less protein for binding and
increased drug sensitivity.
CYP450 inducer - (ANSWER)A drug that increases enzyme activity and speeds up metabolism (e.g.,
rifampin, phenytoin).
Dosing interval - (ANSWER)Based on the drug's half-life (T½).
Loading dose - (ANSWER)Used to quickly reach therapeutic levels for drugs with long half-lives.