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NURS 480: Advanced Medical-Surgical Nursing II - Comprehensive Exam 3| A Review of 402 Real Multiple-Choice Questions with Solutions with Clinical Rationale Generated from Past Exams| Updated 2026/2027| Guaranteed Pass (Brand New!!)- 174 Pages

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Are you preparing for your NURS 480 Advanced Med-Surg Exam 3? Do you want to guarantee your success on the 2026/2027 exam? This all-in-one study guide is meticulously designed to provide you with everything you need to ace your test. This 174-page document is your ultimate review, featuring 402 realistic multiple-choice questions generated and refined from past exams, complete with detailed clinical rationales for every answer. The Q&A format helps you not just memorize facts, but deeply understand the pathophysiology and nursing interventions required for advanced medical-surgical nursing. NURS 480: Advanced Medical-Surgical Nursing II - Comprehensive Exam 3| A Review of 402 Real Multiple-Choice Questions with Solutions with Clinical Rationale Generated from Past Exams| Updated 2026/2027| Guaranteed Pass (Brand New!!)- 174 Pages Table of Contents Section 1: Gastrointestinal System Changes & Diagnostic Procedures • Questions 1-40 Section 2: Gastroesophageal Reflux Disease & Hiatal Hernia • Questions 41-80 Section 3: Gastritis & Peptic Ulcer Disease • Questions 81-130 Section 4: Gastric Surgery & Post-Operative Complications • Questions 131-160 Section 5: Irritable Bowel Syndrome & Colorectal Cancer • Questions 161-200 Section 6: Bowel Obstruction & Peritonitis • Questions 201-230 Section 7: Inflammatory Bowel Disease • Questions 231-260 Section 8: Cirrhosis & Hepatic Complications • Questions 261-310 Section 9: Gallbladder & Pancreatic Disorders • Questions 311-350 Section 10: Renal System Disorders • Questions 351-402 ________________________________________ Multiple Choice Section 1: Gastrointestinal System Changes & Diagnostic Procedures Question 1 A nurse is caring for an older adult patient and notes physiological changes associated with aging of the gastrointestinal system. Which finding is consistent with normal age-related GI changes? A) Increased peristalsis and gastric emptying B) Hypertrophy of gastric mucosa C) Atrophy of gastric mucosa D) Decreased size of pancreatic ducts Answer: C) Atrophy of gastric mucosa Rationale: Age-related GI changes include atrophy of the gastric mucosa, decreased peristalsis, distention and dilation of pancreatic ducts, and a decrease in the size and number of hepatic cells. These changes affect digestion, absorption, and drug metabolism. ________________________________________ Question 2 The nurse understands that distention and dilation of pancreatic ducts in the older adult leads to which physiological consequence? A) Increased fat absorption B) Decreased fat absorption C) Enhanced protein metabolism D) Increased carbohydrate digestion Answer: B) Decreased fat absorption Rationale: Distention and dilation of pancreatic ducts leads to decreased fat absorption because the pancreas may not deliver sufficient digestive enzymes to break down fats effectively. ________________________________________ Question 3 A 72-year-old patient is prescribed a new medication. The nurse should consider which age-related change when calculating the appropriate dose? A) Increased number of hepatic cells B) Decreased size and number of hepatic cells C) Enhanced liver blood flow D) Increased hepatic enzyme production Answer: B) Decreased size and number of hepatic cells Rationale: Decrease in size and number of hepatic cells leads to slower drug metabolism, requiring consideration of lower doses or extended dosing intervals in older adults. Question 4 A patient is scheduled for an Upper GI and Small Bowel Series (barium swallow). Which pre-procedure instruction should the nurse provide? A) Eat a light meal 2 hours before the test B) Maintain NPO status for at least 8 hours C) Drink clear liquids up to 1 hour before the test D) Take prescribed opioid analgesics before the test Answer: B) Maintain NPO status for at least 8 hours Rationale: For an Upper GI and Small Bowel Series, the patient should be NPO for at least 8 hours. Opioid analgesics should be held as they decrease peristalsis, and anticholinergics should be held as they dry out the GI tract. The patient drinks 16 ounces of barium before the test. ________________________________________ Question 5 Which medication should be held before an Upper GI and Small Bowel Series because it decreases peristalsis? A) Antacids B) Opioid analgesics C) Proton pump inhibitors D) Histamine receptor antagonists Answer: B) Opioid analgesics Rationale: Opioid analgesics decrease peristalsis and should be held before an Upper GI series to ensure proper visualization of the GI tract. Anticholinergics should also be held because they dry out the GI tract. ________________________________________ Question 6 Following an Upper GI and Small Bowel Series, what instruction is most important for the nurse to provide? A) Remain NPO for 24 hours B) Drink large amounts of fluids C) Take a laxative immediately D) Resume normal diet immediately Answer: B) Drink large amounts of fluids Rationale: Drinking large amounts of fluids post-procedure decreases the risk of barium impaction. Barium can harden and cause obstruction if not adequately flushed from the GI tract.

Content preview

NURS 480: Advanced Medical-Surgical
Nursing II - Comprehensive Exam 3|
A Review of 402 Real Multiple-Choice
Questions with Solutions with Clinical
Rationale Generated from Past Exams|
Updated 2026/2027| Guaranteed Pass
(Brand New!!)- 174 Pages

Table of Contents
Section 1: Gastrointestinal System Changes & Diagnostic Procedures
• Questions 1-40
Section 2: Gastroesophageal Reflux Disease & Hiatal Hernia
• Questions 41-80
Section 3: Gastritis & Peptic Ulcer Disease
• Questions 81-130
Section 4: Gastric Surgery & Post-Operative Complications
• Questions 131-160
Section 5: Irritable Bowel Syndrome & Colorectal Cancer
• Questions 161-200
Section 6: Bowel Obstruction & Peritonitis
• Questions 201-230
Section 7: Inflammatory Bowel Disease
• Questions 231-260
1

,Section 8: Cirrhosis & Hepatic Complications
• Questions 261-310
Section 9: Gallbladder & Pancreatic Disorders
• Questions 311-350
Section 10: Renal System Disorders
• Questions 351-402




Multiple Choice
Section 1: Gastrointestinal System Changes & Diagnostic Procedures
Question 1
A nurse is caring for an older adult patient and notes physiological changes
associated with aging of the gastrointestinal system. Which finding is consistent
with normal age-related GI changes?
A) Increased peristalsis and gastric emptying
B) Hypertrophy of gastric mucosa
C) Atrophy of gastric mucosa
D) Decreased size of pancreatic ducts
Answer: C) Atrophy of gastric mucosa
Rationale: Age-related GI changes include atrophy of the gastric mucosa,
decreased peristalsis, distention and dilation of pancreatic ducts, and a decrease in
the size and number of hepatic cells. These changes affect digestion, absorption,
and drug metabolism.


Question 2
The nurse understands that distention and dilation of pancreatic ducts in the older
adult leads to which physiological consequence?


2

,A) Increased fat absorption
B) Decreased fat absorption
C) Enhanced protein metabolism
D) Increased carbohydrate digestion
Answer: B) Decreased fat absorption
Rationale: Distention and dilation of pancreatic ducts leads to decreased fat
absorption because the pancreas may not deliver sufficient digestive enzymes to
break down fats effectively.


Question 3
A 72-year-old patient is prescribed a new medication. The nurse should consider
which age-related change when calculating the appropriate dose?
A) Increased number of hepatic cells
B) Decreased size and number of hepatic cells
C) Enhanced liver blood flow
D) Increased hepatic enzyme production
Answer: B) Decreased size and number of hepatic cells
Rationale: Decrease in size and number of hepatic cells leads to slower drug
metabolism, requiring consideration of lower doses or extended dosing intervals in
older adults.


Question 4
A patient is scheduled for an Upper GI and Small Bowel Series (barium swallow).
Which pre-procedure instruction should the nurse provide?
A) Eat a light meal 2 hours before the test
B) Maintain NPO status for at least 8 hours
C) Drink clear liquids up to 1 hour before the test
D) Take prescribed opioid analgesics before the test
Answer: B) Maintain NPO status for at least 8 hours


3

, Rationale: For an Upper GI and Small Bowel Series, the patient should be NPO
for at least 8 hours. Opioid analgesics should be held as they decrease peristalsis,
and anticholinergics should be held as they dry out the GI tract. The patient drinks
16 ounces of barium before the test.


Question 5
Which medication should be held before an Upper GI and Small Bowel Series
because it decreases peristalsis?
A) Antacids
B) Opioid analgesics
C) Proton pump inhibitors
D) Histamine receptor antagonists
Answer: B) Opioid analgesics
Rationale: Opioid analgesics decrease peristalsis and should be held before an
Upper GI series to ensure proper visualization of the GI tract. Anticholinergics
should also be held because they dry out the GI tract.


Question 6
Following an Upper GI and Small Bowel Series, what instruction is most important
for the nurse to provide?
A) Remain NPO for 24 hours
B) Drink large amounts of fluids
C) Take a laxative immediately
D) Resume normal diet immediately
Answer: B) Drink large amounts of fluids
Rationale: Drinking large amounts of fluids post-procedure decreases the risk of
barium impaction. Barium can harden and cause obstruction if not adequately
flushed from the GI tract.



4

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