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what is SLE?
ANSWERS: a chronic multi-symptom autoimmune disease
where are the symptoms of SLE?
ANSWERS: they are diverse with inflammation affecting multiple
organ systems
what kind of disease is SLE?
ANSWERS: it is a waxing and waning disease
,Patho of Lupus briefly
ANSWERS: antibody-antigen complexes deposited in
microvasculature and basement membrane of nephrons -->
these antigens include proteins normally protected inside the
cell called nuclear antigens --> complement proteins attract
neutrophils and trigger inflammation
common symptoms of SLE
ANSWERS: frequent fevers, photophobia (light sensitivity), anxiety,
depression, personality changes, mental health changes, nausea,
vomiting, GI discomfort
common flare up triggers for lupus
ANSWERS: sunlight, pregnancy, stress
SLE symptoms in the head
ANSWERS: hair loss, low fevers, impaired saliva production,
butterfly rash, mental health changes, visual changes, fatigue, and
seizures
,SLE symptoms in the immune system
ANSWERS: lymphadenopathy (inflammed lymph nodes)
SLE hematological symptoms
ANSWERS: anemia and thrombocytopenia (low platelet count)
SLE heart symptoms
ANSWERS: pericarditis d/t lots of small vasculature
SLE lung symptoms
ANSWERS: chest pain that needs immediate medical attention,
pleuritis, and pleural effusion d/t inflammation
SLE GI symptoms
ANSWERS: N/V, IBS, diarrhea, sterile peritonitis (infection of
the abdominal cavity without infectious pathogens)
SLE joint symptoms
ANSWERS: pain and swelling
, SLE Kidney symptoms
ANSWERS: protein and blood in the urine d/t blood vessels being
blocked by neutrophils
SLE finger/toe symptoms
ANSWERS: they can turn blue
risk factors for SLE
ANSWERS: hispanic, physical trauma, chronic stress, and must have
the genetic component