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, interferon alfa-2b, peginterferon
interferon gamma-2b, peginterferon
alfa 2a, lamivudine, adefovir,
gamma-2a, amantadine, rimantadine
entecavir, telbivudine, tenofovir
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Term
What is the induction (initial/intensive) phase of TB treatment?
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-Clavulanic acid, tazobactam, sulbactam
-no active against mrsa
-given with penicillins (ampicillin/sulbactam, amoxicillin-clavulanic acid,
piperacillin/tazobactam- effective against pseudomonas)
-Metronidazole 500 mg twice daily for 7 days for women
-Metronidazole 2 g orally in a single dose for men.
o Alternative regimen for women and men
-tinidazole 2 g orally in a single dose.
-Eliminates actively dividing extracellular tubercle bacilli and thereby renders
the sputum noninfectious
-Lasts 8 weeks
-Drugs: isoniazid, rifampin, pyrazinamide, and ethambutol
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, Recommended:
metronidazole ge. 0.75% one full applicator intravaginally once daily for 5 days
o Pregnant women:
-Only oral clindamycin and metronidazole
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Term
What are the therapeutic indications of sulfonamides?
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Only used for life threatening
infections in which safer drugs are primary use: UTIs
ineffective or contraindicated
disulfuram like reaction with alcohol
Reversible bone marrow depression
-BB warning: increased carcinogenic
& fatal aplastic anemia
risk in mic and rats
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Term
First generation cephalosporins: names
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Penicillin's, cephalosporins, carbapenems, vancomycin, telavancin, monobactam,
Fosfomycin (monurol)
Destroyed by beta lactamases
-cefadroxil, cefazolin, cephalexin
-Less sensitive to destruction by beta-lactamases
-cefaclor, cefotetan, cefoxitin, cefprozil, cefuroxime, cefmetazole, cefonicid,
cefotetan and loracarbef
Very Finely Proficient At Cell Murder
-Vancomycin
-Fluoroquinolones
-Penicillin
-Aminoglycosides
-Cephalosporins
-Metronidazole
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