BANK| BLOOD & MARROW TRANSPLANT CERTIFIED
NURSE (BMTCN) EXAM PREP WITH COMPLETE EXAM
QUESTIONS AND CORRECT DETAILED ANSWERS (VERIFIED
ANSWERS) ALREADY GRADED A+
Hematopoietic stem cells are primarily responsible for ______.
......ANSWER......Blood cell production
Myeloid lineage gives rise to RBCs, platelets, and ______ cells.
......ANSWER......Granulocytes
T-lymphocytes function mainly in ______ immunity.
......ANSWER......Cell-mediated
Graft-versus-tumor effect refers to donor immune cells attacking
______ cells. ......ANSWER......Malignant
Patient receives own stem cells back after high-dose chemo. Type?
......ANSWER......Autologous transplant
HLA matching is essential for evaluating ______ compatibility.
......ANSWER......Histocompatibility
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,Natural killer cells are part of ______ immunity. ......ANSWER......Innate
GVHD stands for ______. ......ANSWER......Graft-versus-host disease
Allogeneic transplant involves stem cells from a ______ donor.
......ANSWER......Genetically different
Sibling donor match identified. Transplant type?
......ANSWER......Matched related donor (MRD)
CAR-T therapy uses genetically modified ______ cells. ......ANSWER......T
Bone marrow is a primary site of ______ cell production.
......ANSWER......Hematopoietic
MURD means matched ______ donor. ......ANSWER......Unrelated
Umbilical cord blood used as stem cell source. Type?
......ANSWER......Cord blood transplant
Haploidentical donor shares ______% HLA match. ......ANSWER......50
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,Stem cell mobilization increases cells in ______ blood.
......ANSWER......Peripheral
CD34+ cells are markers of ______ stem cells.
......ANSWER......Hematopoietic
Patient with leukemia requires transplant. Indication is ______ disease.
......ANSWER......Malignant
Aplastic anemia is a ______ indication for transplant.
......ANSWER......Non-malignant
Immune reconstitution refers to restoration of ______ function.
......ANSWER......Immune
Conditioning regimen is given before ______ infusion.
......ANSWER......Stem cell
Donor stem cells reject host tissue. This is called ______.
......ANSWER......GVHD
Graft-versus-leukemia effect is also called ______ benefit.
......ANSWER......Therapeutic
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, Histocompatibility is based on matching ______ antigens.
......ANSWER......Human leukocyte
Peripheral blood stem cells are collected via ______.
......ANSWER......Apheresis
Patient receives reduced-intensity chemo before transplant. Regimen
type? ......ANSWER......Non-myeloablative
Umbilical cord blood has higher ______ tolerance. ......ANSWER......HLA
mismatch
Donor selection prioritizes HLA ______ match.
......ANSWER......Compatibility
Engraftment is defined as recovery of ______ counts.
......ANSWER......Blood
No sibling donor found; registry used. Donor type?
......ANSWER......MURD
CAR-T therapy targets ______ antigens on tumor cells.
......ANSWER......Specific
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