s s s s s s s
,ABRAMS' CLINICAL DRUG THERAPY: RATIONALES FOR NURSING PRACTICE
s s s s s s s
,ABRAMS' CLINICAL DRUG THERAPY: RATIONALES FOR NURSING PRACTICE
s s s s s s s
, ABRAMS' CLINICAL DRUG THERAPY: RATIONALES FOR NURSING PRACTICE
s s s s s s s
Chapter1,TheFoundationofPharmacology:QualityandSafety
s s s s s s s s
1. A woman diagnosed with obsessive–compulsive disorder has been prescribed oral
s s s s s s s s s
paroxetine hydrochloride. What is the expected effect for this prescription?
s s s s s s s s s s
A. Curative effect on symptoms s s s
B. Systemic effect on symptoms s s s
C. Localeffect on symptoms s s s
D. Parenteral effect on symptoms s s s
ANS: B ss
Rationale: Drugs that produce systemic effects are taken into the body, circulated through the
s s s s s s s s s s s s s
bloodstream to their sites of action in various body tissues, and eventually eliminated from the
s s s s s s s s s s s s s s s
body. Curative agents are given to cure a disease process. In this case, paroxetine hydrochloride
s s s s s s s s s s s s s s s
will control the symptoms but not cure the disorder. Drugs with local effects, such as sunscreen and
s s s s s s s s s s s s s s s s s
local anesthetics, act mainly at the site of application. Paroxetine hydrochloride is not
s s s s s s s s s s s s s
administered parenterally. Parenteral agents are administered subcutaneously, intramuscularly,
s s s s s s s s
or intravenously.
s s
PTS: 1 REF: p. 3, Introduction OBJ: 1 s s
NAT: Client Needs: Physiological Integrity: Pharmacological and ParenteralTherapies TOP:
s s s s s s s s s
Chapter: 1: The Foundation of Pharmacology: Qualityand Safety s s s s s s s s
KEY: Integrated Process: Nursing Process
s s s s
BLM: Cognitive Level: Understand
s s NOT: Multiple Choice s s s s
2. A client has been prescribed an antibiotic. This medication is a naturallyoccurring
s s s s s s s s s s s s
substance that has been cheGmRicA
alDlyEm
SoBdOifOieSd.TWhaOtM
.C is another name for this type of medication?
s s s s s s s s s s s s
A. Synthetic drug s
B. Semisynthetic drug s
C. Biotechnologydrug s
D. Prototype drug s
ANS: B ss
Rationale: Semisynthetic drugs (e.g., many antibiotics) are naturally occurring substances that
s s s s s s s s s s
have been chemically modified. Synthetic drugs are more standardized in their chemical
s s s s s s s s s s s s
scharacteristics, more consistent in their effects, and less likely to produce allergic reactions. s s s s s s s s s s s s
sBiotechnologydrugs involve manipulating DNA and RNA and recombining genes into hybrid s s s s s s s s s s s
molecules that can be inserted into living organisms. Prototype drugs are the first drug of a
s s s s s s s s s s s s s s s s
particular group to be developed.
s s s s s
PTS: 1 REF: p. 3, Drug Sources OBJ: 1 s s s
NAT: Client Needs: Physiological Integrity: Pharmacological and ParenteralTherapies
s s s s s s s s
sTOP: Chapter: 1: The Foundation of Pharmacology: Qualityand Safety s s s s s s s s
KEY: Integrated Process: Nursing Process
s s s s
BLM: Cognitive Level: Understand
s s NOT: Multiple Choice s s s s
3. Which classification applies to morphine? s s s s
A. Central nervous system depressant s s s
B. Central nervous system stimulant s s s
ABRAMS' CLINICAL DRUG THERAPY: RATIONALES FOR NURSING PRACTICE
s s s s s s s