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Critical Care Nursing (Neonatal) (CCN(C) Exam Questions And Correct Answers (Verified Answers) Plus Rationales 2026|2027 Q&A

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Pass your Critical Care Nursing exam with these 100 neonatal practice questions and correct answers. Master NICU protocols, resuscitation, respiratory support, sepsis, and neonatal pharmacology.Critical care nursing, Neonatal exam, NICU nurse study, Neonatal resuscitation, RNC-NIC prep, Neonatal certification, NICU practice test, Neonatal pharmacology, Premature infant care, Respiratory distress syndrome, Neonatal sepsis, NICU nursing exam, Neonatal nurse practitioner, NICU certification, Neonatal resuscitation program

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Institution
Critical Care Nursing
Course
Critical care nursing

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Critical Care Nursing (Neonatal) (CCN(C) P
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ractice Exam Questions And Correct Answ
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ers (Verified Answers) Plus Rationales 202
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6|2027 Q&A | Instant Download Pdf
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1. A term neonate is apneic at birth. First step in neonatal resuscitation is
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:
a. Chest compressions
v




b. Endotracheal intubation v




c. Provide positive-pressure ventilation (PPV)
v v v




d. Administer epinephrine
v




Answer: c. Provide positive-pressure ventilation (PPV)
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, Rationale: PPV is indicated when the neonate is apneic or has inadequa
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te respirations to establish effective ventilation.
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2. Initial oxygen concentration for PPV in term newborns should be:
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a. 100%
b. 21–30%
c. 40–60%
d. 80–100%
Answer: b. 21–30% v v




Rationale: Start low for term infants and titrate by pulse oximetry to av
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oid hyperoxia.
v




3. Heart rate after birth guides resuscitation. If HR <60 bpm despite e
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ffective ventilation, next step is:
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a. Continue ventilation only v v




b. Begin chest compressions and coordinate with ventilation
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c. Give surfactantv




d. Start cooling v




Answer: b. Begin chest compressions and coordinate with ventilation
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Rationale: Compress at a 3:1 ratio with ventilations when HR remains
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<60 bpm despite adequate ventilation.
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4. Surfactant therapy is most appropriate for neonates with:
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a. Transient tachypnea of the newborn v v v v




b. Respiratory distress syndrome (RDS) from surfactant deficiency
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c. Meconium aspiration without RDS v v v

, d. Bronchiolitis
Answer: b. Respiratory distress syndrome (RDS) from surfactant deficie
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ncy
Rationale: Exogenous surfactant reduces alveolar surface tension in pr
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eterm RDS and improves oxygenation.
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5. Optimal target preductal oxygen saturation at 5 minutes of life is a
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pproximately:
a. 45%
b. 60%
c. 80–85%
d. 95%
Answer: c. 80–85% v v




Rationale: Normal transitional SpO2 values rise gradually; targets guid
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e oxygen titration during resuscitation.
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6. For thermoregulation, a very low birth weight infant should be placed in
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:
a. Open crib at room temperature
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b. Bassinet with warm blankets v v v




c. Radiant warmer or incubator with servo control and plastic wrap f
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or delivery
v




d. On the mother’s chest only
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Answer: c. Radiant warmer or incubator with servo control and pl
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astic wrap for delivery
v v v

, Rationale: Preterm and VLBW infants lose heat rapidly; servo-
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controlled devices and plastic wrap reduce heat loss.
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7. Umbilical arterial catheter placement is indicated primarily to:
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a. Deliver enteral feedings v v




b. Monitor arterial blood pressure and obtain blood gases
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c. Give high-volume parenteral nutrition
v v v




d. Remove excess air from abdomen v v v v




Answer: b. Monitor arterial blood pressure and obtain blood gases Rati
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onale: UACs provide reliable arterial access for continuous BP monitori
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ng and blood sampling.
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8. Central line-associated bloodstream infection prevention includes:
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a. Routine line changes every 24 hoursv v v v v




b. Strict aseptic insertion technique and line maintenance bundles
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c. Using an umbilical catheter indefinitely
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d. Frequent dressing removal to inspect site daily
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Answer: b. Strict aseptic insertion technique and line maintenance bun
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dles
Rationale: Bundles (hand hygiene, maximal barriers, chlorhexidine, ste
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rile dressing) reduce CLABSI rates.
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9. Neonatal hypoglycemia is commonly defined as blood glucose below:
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a. 3.0 mmol/L (54 mg/dL) for all ages
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b. 2.6 mmol/L (47 mg/dL) in the first 48 hours
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c. 1.0 mmol/L (18 mg/dL) at any time
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Institution
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