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Pathophysiology Exam 1 Practice Problems 85 Q&A 2026

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Master your Pathophysiology Exam 1 with 85 practice questions and detailed answers covering cell injury, inflammation, immunity, hematology, and tissue repair. Updated for 2026 nursing curriculum. Perfect for BSN, ADN, and PN students preparing for NCLEX. Instant digital download. Compatible with Chamberlain, Walden, South College, and standard nursing programs. Includes rationales for cell adaptation, stress response, wound healing, immunoglobulins, anemia types, and hypersensitivity reactions.

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Pathophysiology Exam 1 Practice Problems
85 QUESTIONS AND ANSWERS 2026
UPDATE



g Agpatientgisgfoundgtoghaveglivergdisease,gresultinggingthegremovalgofgaglobegofghisgliver.gAdaptationgtog
thegreducedgsizegofgtheglivergleadsgtog ofgthegremainingglivergcells.


A. Metaplasia
B. Organgatrophy
C. Compensatoryghyperplasia
D. Physiologicghyperplasiag-gANS>>C


Angoldergadultgpatientgcomesgtogthegclinicgcomplaininggofgnotgbeinggablegtogdogwhatghegusedgtogbegab
legto.gYougknowgthatgnormalgchangesgassociatedgwithgagingginclude:g(Selectgallgthatgapply.)


A. Improvedgbloodgflow
B. Slowedgmetabolicgrate
C. Decreasedgbraingweight
D. Improvedgnervegfibergconduction
E. Lessgrespiratorygcapacityg-gANS>>B,gC,gE


Ag20-year-
oldgcollegegstudentghasgpresentedgtoghergcampusgmedicalgclinicgforgagscheduledgPapgsmear.gThegclin
iciangwhogwillginterpretgthegsmeargwillgexaminegcellgsamplesgforgevidencegof:


A. Changesgingcellgshape,gsize,gandgorganization
B. Presencegofgunexpectedgcellgtypes
C. Ischemicgchangesgingcellgsample
D. Abnormallyghighgnumbersgofgcellsg-gANS>>A


Thegparentsgofgag4-year-
oldggirlghavegsoughtgcaregbecausegtheirgdaughterghasgadmittedgtogchewinggandgswallowinggimporte
dgtoygfigurinesgthatghavegbeengdeterminedgtogbegmadegofglead.gWhichgofgthegfollowinggbloodgtestsgsh
ouldgthegcaregteamgprioritize?


A. Whitegbloodgcellglevelsgwithgdifferential
B. Redgbloodgcellglevelsgandgmorphology
C. Ureagandgcreatinineglevels
D. Livergfunctiongpanelg-
ANS>>BgLeadg-
g


>ganemia,gRBCglysis

,Yougknowgit'sgnotgAgbecausegtheregisgnoginfectionginvolved.gCgisgfocusedgongkidneygfunctiongwhilegDgis
focusedgonglivergfunction.gBothgofgthesegwouldgbegimportantgingthegcasegofgleadgpoisoninggBUTgthegpri
g


oritygANS>>gisgB,gbecausegyougneedgfirstgtogaddressgthegmostglife-
threateninggpatientgneeds.gTheglittleggirlgingthisgquestiongcanggogintogshockgorgsuffergpermanentgorgan
g damagegifghergRBCsgareglow.


Agpatientgwithgseveregperipheralgvasculargdiseaseghasgdevelopedgsignsgofgdryggangrenegongtheggreatgt
oegofgonegfoot.gWhichgofgthegfollowinggpathophysiologicgprocessesgmostglikelygcontributedgtogthisgdia
gnosis?


A. Inappropriategactivationgofgapoptosis
B. Bacterialginvasion
C. Impairedgarterialgbloodgsupply
D. Metaplasticgcellulargchangesg-gANS>>B


Remembergthatgit'sgnotgCgbecausegtoghaveggangrene,gyougmustghaveginfection


Althoughgstressgexposureginitiatesgintegratedgresponsesgbygmultiplegsystems,gthegmostgimportantgc
hangesgaregfirstgactivatedgbygwhichgsystem?


A. Pulmonary
B. Gastrointestinal
C. Neuroendocrine
D. Cardiovascularg-gANS>>C


Whichgmanifestationgofgstressgreflectsgthegnon-specificgfightgorgflightgresponse?


A. Decreasedgpupillaryglightgresponse
B. IncreasedgGIgmotility
C. Decreasedgshort-termgmemory
D. Increasedgcardiopulmonarygratesg-gANS>>D


Thisgwouldgfallgundergphysiologicgresponsesgtogstress!!gSlideg25gingyourglecturegpowerpointg


Stress-inducedgcortisolghormonegsecretiongisgassociatedgwith:


A. Increasedggrowthghormoneglevel
B. Regulationgofgthegstressgresponse
C. Increasedgthyroid-stimulatingghormone
D. Depressedgadrenalgglandgfunctiong-gANS>>B



Yougknowgit'sgnotgAgbecausegIgmentionedgingangearliergslidegthatggrowthghormoneglevelsgdecreasegwi
thgstress.gWegdidn'tgmentiongthyroid-
stimulatingghormonegasgonegofgthegonesgassociatedgwithgthegstressgrepsonsegsogyougcangprettygmuc
hgassumegthat'sgnotgright.gAndgwegknowgadrenalgfunctiongisgnotgdepressedgbecausegACTHgfromgtheg
anteriorgpituitarygstimulatesgthegadrenalgglandsgtogreleasegcortisol.

, Whichgofgthegfollowinggfactorsgaregknowngtogcontributegtogangindividual'sgabilitygtogadaptgtogstress?g(
Selectgallgthatgapply.)


A. Ethnicity
B. Age
C. Socioeconomicgstatus
D. Gender
E. Healthgstatusg-gANS>>B,gC,gD,gE


"Abilitygtogadaptgtogstress"g=gmediatinggfactors!gSlideg28gofgthisgpowerpoint


Twogpeoplegexperiencegthegsamegstressorgyetgonlygonegisgablegtogcopegandgadaptgadequately.gAngexa
mplegofgthegpersongwithgangincreasedgcapacitygtogadaptgisgthegonegwith:


A. Agsensegofgpurposeginglife
B. Circadiangrhythmgdisruption
C. Age-relatedgrenalgdysfunction
D. Excessivegweightggaingorglossg-gANS>>A


Backgtogmediatinggfactors.gWhichgofgthesegthingsgdogyougthinkgwouldghelpgagpersongdealgwithgstress
?gDisruptiongingsleepgcycleg(B)gwillgdefinitelygnotghelp,gage-
relatedgrenalgdysfunctiong(C)gisgangindicatorgofgpoorghealthgstatusgwhichgalsogwouldgnotghelp,gandgex
cessivegweightgchangesg(D)garegalsoglikelygtogcausegmoregstressgthangalleviategit.


Thegcharacteristic,glocalizedgcardinalgsignsgofgacuteginflammationginclude:g(Selectgallgthatgapply.)


A. Redness
B. Fatigue
C. Swelling
D. Warmth
E. Feverg-gANS>>A,gC,gD


Thegcellulargstagegofgacuteginflammationgisgmarkedgbygthegmovementgofgleukocytesgintogthegarea.gWh
ichgofgthegfollowinggcellsgarrivesgfirstgandginggreatgnumbers?


A. Basophils
B. Lymphocytes
C. Neutrophils
D. Plateletsg-gANS>>C


Whichgofgthegfollowinggmediatorsgofginflammationgcausesgincreasedgcapillarygpermeabilitygandgpain?


A. Serotonin
B. Histamine
C. Bradykinin
D. Nitricgoxideg-gANS>>C

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