Amelie Hollier and Advanced Practice
Education Associates (APEA) - Latest
2025/2026 Edition for First-Time Success
First, let's look at the actual structure of the exam to
guide your studying. According to official APEA
documentation, the exam is a competency-based
assessment used to gauge readiness for clinical practice.
It is broken down into three equal domains:
| Domain | Percentage of Exam | What It Tests |
, | :--- | :--- | :--- |
| **Physical Assessment** | **33%** | Your ability to
obtain subjective (history) and objective (physical exam)
data. This includes interview techniques, recognizing
normal vs. abnormal findings, and knowing what signs
and symptoms relate to a condition. |
| **Pharmacotherapeutics** | **33%** | Your ability to
make safe and effective prescribing choices. This includes
selecting the best medication, understanding drug
classes, side effects, interactions, and patient education.
|
| **Pathophysiology** | **33%** | Your knowledge of
the etiology, pathogenesis, and clinical manifestations of
disease. This domain asks you to relate altered
physiology to the clinical presentation of a patient. |
The exam has a total of **75 questions** (25 per
domain), and a score of **67% or higher** indicates
adequate knowledge.