COMSAE Phase 1 Form 105 Questions With
Correct Answers (Verified Answers) Plus
Rationales 2026 Q&A | Instant Download Pdf
Question 1
A 65-year-old man presents with chest pain radiating to his left arm.
ECG shows ST-segment elevation in leads II, III, and aVF. Which coronary
artery is most likely occluded?
A. Left anterior descending artery
B. Right coronary artery
C. Left circumflex artery
D. Posterior descending artery
Correct answer: B
Rationale: Inferior wall myocardial infarction is indicated by ST
elevation in leads II, III, and aVF. The right coronary artery most
commonly supplies the inferior wall of the heart in right-dominant
circulation.
,Question 2
A patient presents with fatigue, pallor, and a mean corpuscular volume
(MCV) of 72 fL. Which condition is most likely?
A. Vitamin B12 deficiency
B. Iron deficiency anemia
C. Aplastic anemia
D. Folate deficiency
Correct answer: B
Rationale: Microcytic anemia (MCV < 80 fL) is most commonly caused
by iron deficiency, often due to chronic blood loss or inadequate
intake.
Question 3
Which organism is most commonly associated with peptic ulcer
disease?
A. Helicobacter pylori
B. Escherichia coli
C. Staphylococcus aureus
D. Clostridium difficile
,Correct answer: A
Rationale: Helicobacter pylori infection is a major cause of chronic
gastritis and peptic ulcer disease through urease production and
mucosal damage.
Question 4
A 30-year-old woman presents with exophthalmos, heat intolerance,
and weight loss. What is the most likely diagnosis?
A. Hashimoto thyroiditis
B. Graves disease
C. Subacute thyroiditis
D. Thyroid cancer
Correct answer: B
Rationale: Graves disease is an autoimmune hyperthyroidism
characterized by TSH receptor-stimulating antibodies leading to
increased thyroid hormone production and ophthalmopathy.
Question 5
Which vitamin deficiency causes night blindness?
, A. Vitamin A
B. Vitamin D
C. Vitamin C
D. Vitamin K
Correct answer: A
Rationale: Vitamin A is essential for retinal phototransduction via
rhodopsin; deficiency leads to impaired dark adaptation and night
blindness.
Question 6
A patient has a positive Romberg test. Which sensory system is most
likely impaired?
A. Cerebellar function
B. Vestibular system or proprioception
C. Basal ganglia
D. Motor cortex
Correct answer: B
Rationale: A positive Romberg test indicates impaired proprioception
or vestibular dysfunction, as vision compensates for balance when
eyes are open.
Correct Answers (Verified Answers) Plus
Rationales 2026 Q&A | Instant Download Pdf
Question 1
A 65-year-old man presents with chest pain radiating to his left arm.
ECG shows ST-segment elevation in leads II, III, and aVF. Which coronary
artery is most likely occluded?
A. Left anterior descending artery
B. Right coronary artery
C. Left circumflex artery
D. Posterior descending artery
Correct answer: B
Rationale: Inferior wall myocardial infarction is indicated by ST
elevation in leads II, III, and aVF. The right coronary artery most
commonly supplies the inferior wall of the heart in right-dominant
circulation.
,Question 2
A patient presents with fatigue, pallor, and a mean corpuscular volume
(MCV) of 72 fL. Which condition is most likely?
A. Vitamin B12 deficiency
B. Iron deficiency anemia
C. Aplastic anemia
D. Folate deficiency
Correct answer: B
Rationale: Microcytic anemia (MCV < 80 fL) is most commonly caused
by iron deficiency, often due to chronic blood loss or inadequate
intake.
Question 3
Which organism is most commonly associated with peptic ulcer
disease?
A. Helicobacter pylori
B. Escherichia coli
C. Staphylococcus aureus
D. Clostridium difficile
,Correct answer: A
Rationale: Helicobacter pylori infection is a major cause of chronic
gastritis and peptic ulcer disease through urease production and
mucosal damage.
Question 4
A 30-year-old woman presents with exophthalmos, heat intolerance,
and weight loss. What is the most likely diagnosis?
A. Hashimoto thyroiditis
B. Graves disease
C. Subacute thyroiditis
D. Thyroid cancer
Correct answer: B
Rationale: Graves disease is an autoimmune hyperthyroidism
characterized by TSH receptor-stimulating antibodies leading to
increased thyroid hormone production and ophthalmopathy.
Question 5
Which vitamin deficiency causes night blindness?
, A. Vitamin A
B. Vitamin D
C. Vitamin C
D. Vitamin K
Correct answer: A
Rationale: Vitamin A is essential for retinal phototransduction via
rhodopsin; deficiency leads to impaired dark adaptation and night
blindness.
Question 6
A patient has a positive Romberg test. Which sensory system is most
likely impaired?
A. Cerebellar function
B. Vestibular system or proprioception
C. Basal ganglia
D. Motor cortex
Correct answer: B
Rationale: A positive Romberg test indicates impaired proprioception
or vestibular dysfunction, as vision compensates for balance when
eyes are open.
