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1. What are the three major lines First: Skin and mucous membranes; Second: Inflammatory re-
of defense in the body? sponse; Third: Immune response.
2. What are the cardinal signs of Heat, pain, edema, redness, and loss of function.
inflammation?
3. What is the primary purpose To isolate the area of injury, remove damaged cells, and elimi-
of inflammation? nate infection-causing microorganisms.
4. What are the types of inflam- Acute, subacute, chronic, and granulomatous inflammation.
mation?
5. What are the three major 1. Increase blood flow to the site of injury; 2. Alert healing
goals of acute inflammation? products to attend to the site; 3. Remove injured tissue and
prepare for repair.
6. What role do chemical medi- They induce vasodilation and increase capillary permeability to
ators play in the vascular re- allow more blood flow to the injured area.
sponse during inflammation?
7.
, Inflammation, Tissue Repair, and Cellular Responses in Pathophysiology
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What indicates that the im- A high white blood cell (WBC) count, or leukocytosis, typically
mune system is responding to >11,000 cells/μL.
inflammation or infection?
8. What is chemotaxis in the con- The movement of cells towards the site of injury in response to
text of the cellular response to chemical signals.
inflammation?
9. What are the phases of heal- 1. Inflammatory phase; 2. Proliferative phase; 3. Remodeling
ing and tissue repair? phase.
10. What is healing by primary in- Wound edges are approximated and closed with sutures or
tention? staples, resulting in fast healing and low infection risk.
11. What is healing by secondary Wound edges are separated and heal from the bottom up,
intention? typically resulting in a larger scar and slower healing.