ing
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1. What is the primary focus of The study of disordered physiological processes associated with
pathophysiology? disease or injury.
2. What is homeostasis? The body's ability to maintain a stable internal environment
despite external changes.
3. What are the two main types Endogenous (internal causes) and Exogenous (external caus-
of disease etiology? es).
4. What is the difference be- Congenital diseases are present at birth, while acquired dis-
tween congenital and ac- eases develop after birth.
quired diseases?
5. What are risk factors in dis- Characteristics that increase the likelihood of disease, which
ease? can be non-modifiable (age, genetics) or modifiable (lifestyle
choices).
6. Define pathology. Structural or functional changes that disrupt homeostasis; the
study of diseases.
7. What is pathogenesis? The mechanism or process by which a disease develops and
progresses.
8. What are clinical manifesta- Symptoms (subjective experiences) and signs (objective find-
tions? ings) of a disease.
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, Pathophysiology of Disease: Cellular Injury, Inflammation, and Wound Hea
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9. What is the difference be- Symptoms are subjective patient-reported experiences, while
tween symptoms and signs? signs are objective, observable findings.
10. What is cellular adaptation? The process by which cells adjust to increased stress through
changes in size, number, or form.
11. What is atrophy? A decrease in cell size due to decreased workload or resources.
12. What causes hypertrophy? An increase in cell size due to increased workload, such as
chronic hypertension.
13. What is hyperplasia? An increase in the number of cells in a tissue or organ.
14. What is metaplasia? A change in the form of cells, often in response to chronic
irritation.
15. What is dysplasia? Abnormal changes in the size, shape, and organization of cells.
16. What are the two classifica- Structural (physical changes) and Functional (impaired function
tions of disease by effect? without structural changes).
17. What is the clinical course of a The pattern of disease progression over time, which can be
disease? acute, chronic, or relapsing.
18. What are sequelae? Long-term or permanent effects that occur after the resolution
of a disease.
19. Define syndrome. A group of signs and symptoms that occur together.
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