KAPLAN NGN ASSESSMENT C PRACTICE TEST QUESTIONS AND CORRECT ANSWERS (VERIFIED ANSWERS) PLUS RATIONALES 2026 Q&A
| INSTANT DOWNLOAD PDF
,Core Domains
Pharmacology Foundations and Pharmacokinetics/Pharmacodynamics
Medication Safety and High-Alert Drug Management
Cardiovascular System Pharmacotherapy
Neurological System Pharmacotherapy
Endocrine System Pharmacotherapy and Diabetes Management
Anti-infective Agents and Antimicrobial Therapy
Oncology Pharmacology and Chemotherapy Safety
Dosage Calculations and Nursing Math
Ethics, Legal Compliance, and Professional Nursing Standards
Clinical Judgment and Real-World Decision-Making
Introduction
,This practice assessment is designed to prepare nursing students and professionals for the Kaplan NGN Assessment C, a comprehensive
pharmacology examination featuring Next Generation NCLEX-style questions. The exam evaluates critical knowledge areas including drug
classifications, pharmacokinetic principles, medication safety protocols, and therapeutic applications across multiple body systems. Questions are
presented in multiple-choice and scenario-based formats that emphasize real-world clinical application, requiring candidates to demonstrate sound
decision-making abilities in authentic healthcare situations. Success on this assessment indicates readiness for safe medication administration and
pharmacotherapy management in clinical practice.*
Section One: Questions 1–100
Question 1
A nurse is administering digoxin to a patient with heart failure. The patient's serum digoxin level is 2.4 ng/mL. Which action should the nurse take
first?
A. Administer the dose as scheduled
B. Hold the dose and notify the provider
C. Recheck the level in 4 hours
D. Provide calcium supplement
🟢 Correct answer: B
🔴 RATIONALE: Normal therapeutic digoxin levels range from 0.5–2.0 ng/mL. A level of 2.4 ng/mL indicates digoxin toxicity, so the nurse must
hold the dose and notify the provider immediately to prevent adverse effects like arrhythmias.
Question 2
Which medication class is contraindicated in patients with bilateral renal artery stenosis?
A. Beta-blockers
B. ACE inhibitors
C. Calcium channel blockers
D. Thiazide diuretics
🟢 Correct answer: B
🔴 RATIONALE: ACE inhibitors can cause acute renal failure in patients with bilateral renal artery stenosis by reducing glomerular filtration
pressure. They are contraindicated in this population due to the risk of worsening renal function.
, Question 3
A patient taking warfarin for deep vein thrombosis reports eating large amounts of leafy greens. Which lab value should the nurse monitor?
A. Platelet count
B. INR (International Normalized Ratio)
C. Hemoglobin
D. White blood cell count
🟢 Correct answer: B
🔴 RATIONALE: Leafy greens contain high levels of vitamin K, which antagonizes warfarin's anticoagulant effect. The INR must be monitored to
assess whether the patient remains within the therapeutic range (typically 2.0–3.0 for DVT).
Question 4
Which drug is the priority treatment for a patient experiencing magnesium sulfate toxicity?
A. Calcium gluconate
B. Sodium bicarbonate
C. Potassium chloride
D. Epinephrine
🟢 Correct answer: A
🔴 RATIONALE: Calcium gluconate is the antidote for magnesium sulfate toxicity. It reverses the effects of hypermagnesemia, including respiratory
depression and loss of deep tendon reflexes.
Question 5
A patient with type 2 diabetes is prescribed metformin. Which condition requires the nurse to hold the medication?
A. Serum creatinine of 1.1 mg/dL
B. Blood glucose of 180 mg/dL
C. Serum creatinine of 1.8 mg/dL
D. Blood pressure of 138/82 mmHg
🟢 Correct answer: C
| INSTANT DOWNLOAD PDF
,Core Domains
Pharmacology Foundations and Pharmacokinetics/Pharmacodynamics
Medication Safety and High-Alert Drug Management
Cardiovascular System Pharmacotherapy
Neurological System Pharmacotherapy
Endocrine System Pharmacotherapy and Diabetes Management
Anti-infective Agents and Antimicrobial Therapy
Oncology Pharmacology and Chemotherapy Safety
Dosage Calculations and Nursing Math
Ethics, Legal Compliance, and Professional Nursing Standards
Clinical Judgment and Real-World Decision-Making
Introduction
,This practice assessment is designed to prepare nursing students and professionals for the Kaplan NGN Assessment C, a comprehensive
pharmacology examination featuring Next Generation NCLEX-style questions. The exam evaluates critical knowledge areas including drug
classifications, pharmacokinetic principles, medication safety protocols, and therapeutic applications across multiple body systems. Questions are
presented in multiple-choice and scenario-based formats that emphasize real-world clinical application, requiring candidates to demonstrate sound
decision-making abilities in authentic healthcare situations. Success on this assessment indicates readiness for safe medication administration and
pharmacotherapy management in clinical practice.*
Section One: Questions 1–100
Question 1
A nurse is administering digoxin to a patient with heart failure. The patient's serum digoxin level is 2.4 ng/mL. Which action should the nurse take
first?
A. Administer the dose as scheduled
B. Hold the dose and notify the provider
C. Recheck the level in 4 hours
D. Provide calcium supplement
🟢 Correct answer: B
🔴 RATIONALE: Normal therapeutic digoxin levels range from 0.5–2.0 ng/mL. A level of 2.4 ng/mL indicates digoxin toxicity, so the nurse must
hold the dose and notify the provider immediately to prevent adverse effects like arrhythmias.
Question 2
Which medication class is contraindicated in patients with bilateral renal artery stenosis?
A. Beta-blockers
B. ACE inhibitors
C. Calcium channel blockers
D. Thiazide diuretics
🟢 Correct answer: B
🔴 RATIONALE: ACE inhibitors can cause acute renal failure in patients with bilateral renal artery stenosis by reducing glomerular filtration
pressure. They are contraindicated in this population due to the risk of worsening renal function.
, Question 3
A patient taking warfarin for deep vein thrombosis reports eating large amounts of leafy greens. Which lab value should the nurse monitor?
A. Platelet count
B. INR (International Normalized Ratio)
C. Hemoglobin
D. White blood cell count
🟢 Correct answer: B
🔴 RATIONALE: Leafy greens contain high levels of vitamin K, which antagonizes warfarin's anticoagulant effect. The INR must be monitored to
assess whether the patient remains within the therapeutic range (typically 2.0–3.0 for DVT).
Question 4
Which drug is the priority treatment for a patient experiencing magnesium sulfate toxicity?
A. Calcium gluconate
B. Sodium bicarbonate
C. Potassium chloride
D. Epinephrine
🟢 Correct answer: A
🔴 RATIONALE: Calcium gluconate is the antidote for magnesium sulfate toxicity. It reverses the effects of hypermagnesemia, including respiratory
depression and loss of deep tendon reflexes.
Question 5
A patient with type 2 diabetes is prescribed metformin. Which condition requires the nurse to hold the medication?
A. Serum creatinine of 1.1 mg/dL
B. Blood glucose of 180 mg/dL
C. Serum creatinine of 1.8 mg/dL
D. Blood pressure of 138/82 mmHg
🟢 Correct answer: C
