PATHO 502 final exam questions
Study online at https://quizlet.com/_apt0c7
1. The administration of a vaccine to an individual to Innate immunity
reduce the risk for future infections is based on the Passive immunity
principles of Adaptive Immunity
Immunosuppression
2. A macrophage can function as an antigen-presenting Lymphocyte
cell to process an antigen for the Neutrophil
Mast cell
Basophil
3. Selected genes function as tumor suppressors, of Deficient; apoptosis
which an important one is p53. Malignant cells are Deficient; cell division
often _________ in p53, and less likely to undergo Abundant; cell division
___________. Abundant; apoptosis
4. A 54 year old man is being evaluated for a suspect- a-Leukocytosis
ed infection. As part of his work-up, hematological b-Lymphopenia
blood work is obtained, including a differential on c-Increase in the number
white blood cells. Which of the following results is (are) of immature granulocytes
expected if this is an infectious cause? (neutrophils)
Each of the above
Both A and C above
5. A laboratory work-up for a patient with drug-induced Increased reticulocyte
hemolytic anemia would be expected to show a(n) count
Leukocytosis
Decreased reticulocyte
count
Leukopenia
6. William is a 70 year old man is taking a low-dose as- Vitamin K-dependent clot-
pirin daily to reduce his risk of a heart attack or stroke. ting factors
Fibrinogen
, PATHO 502 final exam questions
Study online at https://quizlet.com/_apt0c7
He is at an increased risk for bleeding due to effects Platelets
on Thrombin
7. William is a 70 year old man is taking a low-dose A. a lack of inhibition of
aspirin daily to reduce his risk of a heart attack or thromboxane in platelets,
stroke. He was recently prescribed celecoxib, a COX-2 while inhibiting prostacy-
selective NSAID, for an acute injury to his shoulder clin in vascular smooth
suffered while playing tennis. Based on the theory as muscle.
to why COX-2 selective NSAIDs increase the risk for B. a preferential action
thrombotic events, William is at risk because celecoxib in platelets that increas-
exhibits es the concentration of
thromboxane, increasing
the risk for bleeding.
C. characteristics that
create a proinflammatory
state based on the inhibi-
tion of prostaglandins.
D. Minimal anti-inflam-
matory activity due to a
lack of effect on the COX-1
enzyme.
8. A 32 year old man has been experiencing asthma A. The peak flow result
symptoms for the past week, including cough, wheez- should increase as airflow
ing, and shortness of breath. A peak flow is measured obstruction is reduced.
and reported at 290 (60% of his expected result). He is B. The peak flow result
treated with albuterol, which is a β-2 receptor agonist should decrease as a re-
(stimulates the beta receptors resulting in relaxation sult of increased mucus
of bronchial smooth muscle). Based on your under- production.
standing of the pathophysiological features of asth- C. The peak flow is not
ma, which of the following would you predict? expected to change be-
cause albuterol's effect is
, PATHO 502 final exam questions
Study online at https://quizlet.com/_apt0c7
not specific for airflow ob-
struction.
D. The peak flow result
should increase because
of an expected increase in
heart rate.
9. Which of the following features usually predicts the A. Local, aggressive inva-
need to use chemotherapy (as opposed to surgery) to sion of tissue
treat a malignancy? B. Metastasis
C. Age of patient
D. Co-morbidities
10. Which of the following statements is (are) true regard- A. Acute lymphocytic
ing acute leukemias? leukemia (ALL) is the
most common pediatric
leukemia.
B. Acute leukemias are
associated with a higher
percentage of immature
lymphocytes compared to
chronic leukemias.
C. Neutropenia or ane-
mia is not commonly seen
in patients with acute
leukemias.
D. Each of the above is
true
E. Only A and B above is
true
11.
, PATHO 502 final exam questions
Study online at https://quizlet.com/_apt0c7
Which of the following statements is (are) true about A. Characterized by the
chronic lymphocytic leukemia (CLL)? presence of the Philadel-
phia Chromosome.
B. Most commonly affects
elderly adults in their 70s.
C. Generally requires ag-
gressive treatment to im-
prove survival.
D. Each of the above.
E. Both A and C above
12. Which of the following statements is (are) true when A. NHL is more common
comparing Hodgkin lymphomas to non-Hodgkin lym- that Hodgkin lymphoma.
phomas (NHL)? B. NHL tends to
spread more aggressive-
ly to distant organs,
while Hodgkin lymphoma
demonstrates a more or-
derly spread to contigu-
ous lymph nodes.
C. The prognosis is better
for Hodgkin patients com-
pared to non-Hodgkin pa-
tients.
D. Each of the above.
E. None of the above.
13. Females are at greater risk for rheumatoid arthritis A. True
while systemic lupus erythematosus (SLE) is predomi- B. False
nately a disease of males.
14.
Study online at https://quizlet.com/_apt0c7
1. The administration of a vaccine to an individual to Innate immunity
reduce the risk for future infections is based on the Passive immunity
principles of Adaptive Immunity
Immunosuppression
2. A macrophage can function as an antigen-presenting Lymphocyte
cell to process an antigen for the Neutrophil
Mast cell
Basophil
3. Selected genes function as tumor suppressors, of Deficient; apoptosis
which an important one is p53. Malignant cells are Deficient; cell division
often _________ in p53, and less likely to undergo Abundant; cell division
___________. Abundant; apoptosis
4. A 54 year old man is being evaluated for a suspect- a-Leukocytosis
ed infection. As part of his work-up, hematological b-Lymphopenia
blood work is obtained, including a differential on c-Increase in the number
white blood cells. Which of the following results is (are) of immature granulocytes
expected if this is an infectious cause? (neutrophils)
Each of the above
Both A and C above
5. A laboratory work-up for a patient with drug-induced Increased reticulocyte
hemolytic anemia would be expected to show a(n) count
Leukocytosis
Decreased reticulocyte
count
Leukopenia
6. William is a 70 year old man is taking a low-dose as- Vitamin K-dependent clot-
pirin daily to reduce his risk of a heart attack or stroke. ting factors
Fibrinogen
, PATHO 502 final exam questions
Study online at https://quizlet.com/_apt0c7
He is at an increased risk for bleeding due to effects Platelets
on Thrombin
7. William is a 70 year old man is taking a low-dose A. a lack of inhibition of
aspirin daily to reduce his risk of a heart attack or thromboxane in platelets,
stroke. He was recently prescribed celecoxib, a COX-2 while inhibiting prostacy-
selective NSAID, for an acute injury to his shoulder clin in vascular smooth
suffered while playing tennis. Based on the theory as muscle.
to why COX-2 selective NSAIDs increase the risk for B. a preferential action
thrombotic events, William is at risk because celecoxib in platelets that increas-
exhibits es the concentration of
thromboxane, increasing
the risk for bleeding.
C. characteristics that
create a proinflammatory
state based on the inhibi-
tion of prostaglandins.
D. Minimal anti-inflam-
matory activity due to a
lack of effect on the COX-1
enzyme.
8. A 32 year old man has been experiencing asthma A. The peak flow result
symptoms for the past week, including cough, wheez- should increase as airflow
ing, and shortness of breath. A peak flow is measured obstruction is reduced.
and reported at 290 (60% of his expected result). He is B. The peak flow result
treated with albuterol, which is a β-2 receptor agonist should decrease as a re-
(stimulates the beta receptors resulting in relaxation sult of increased mucus
of bronchial smooth muscle). Based on your under- production.
standing of the pathophysiological features of asth- C. The peak flow is not
ma, which of the following would you predict? expected to change be-
cause albuterol's effect is
, PATHO 502 final exam questions
Study online at https://quizlet.com/_apt0c7
not specific for airflow ob-
struction.
D. The peak flow result
should increase because
of an expected increase in
heart rate.
9. Which of the following features usually predicts the A. Local, aggressive inva-
need to use chemotherapy (as opposed to surgery) to sion of tissue
treat a malignancy? B. Metastasis
C. Age of patient
D. Co-morbidities
10. Which of the following statements is (are) true regard- A. Acute lymphocytic
ing acute leukemias? leukemia (ALL) is the
most common pediatric
leukemia.
B. Acute leukemias are
associated with a higher
percentage of immature
lymphocytes compared to
chronic leukemias.
C. Neutropenia or ane-
mia is not commonly seen
in patients with acute
leukemias.
D. Each of the above is
true
E. Only A and B above is
true
11.
, PATHO 502 final exam questions
Study online at https://quizlet.com/_apt0c7
Which of the following statements is (are) true about A. Characterized by the
chronic lymphocytic leukemia (CLL)? presence of the Philadel-
phia Chromosome.
B. Most commonly affects
elderly adults in their 70s.
C. Generally requires ag-
gressive treatment to im-
prove survival.
D. Each of the above.
E. Both A and C above
12. Which of the following statements is (are) true when A. NHL is more common
comparing Hodgkin lymphomas to non-Hodgkin lym- that Hodgkin lymphoma.
phomas (NHL)? B. NHL tends to
spread more aggressive-
ly to distant organs,
while Hodgkin lymphoma
demonstrates a more or-
derly spread to contigu-
ous lymph nodes.
C. The prognosis is better
for Hodgkin patients com-
pared to non-Hodgkin pa-
tients.
D. Each of the above.
E. None of the above.
13. Females are at greater risk for rheumatoid arthritis A. True
while systemic lupus erythematosus (SLE) is predomi- B. False
nately a disease of males.
14.
