Banasik: Pathophysiology, 7th Edition
MULTIPLE CHOICE
1. C.Q. was recently exposed to group A hemolytic Streptococcus and subsequently developed a
J J J J J J J J J J J J
pharyngeal infection. His clinic examination reveals an oral temperature of 102.3°F, skin rash,
J J J J J J J J J J J J J
dysphagia, and reddened throat mucosa with multiple pustules. He complains of sore throat,
J J J J J J J J J J J J J
malaise, and joint stiffness. A throat culture is positive for Streptococcus, and antibiotics have been
J J J J J J J J J J J J J J J
prescribed. The etiology of C.Q.’s disease is J J J J J J
a. a sore throat. J J
b. streptococcal infection. J
c. genetic susceptibility. J
d. pharyngitis.
ANS: B J
Etiology refers to the proposed cause or causes of a particular disease process. A sore throat is the
J J J J J J J J J J J J J J J J J J
manifestation of the disease process. Genetic susceptibility refers to inherited tendency to develop
J J J J J J J J J J J J J
a disease. Pharyngitis refers to inflammation of the throat and is also a clinical manifestation of the
J J J J J J J J J J J J J J J J J
disease process. J
2. A 17-year-old college-bound student receives a vaccine against an organism that causes
J J J J J J J J J J J J
meningitis. This is an example of J J J J J
a. primary prevention. J
b. secondary prevention. J
c. tertiaryprevention. J
d. disease treatment. J
ANS: A J
Primaryprevention is prevention of disease byaltering susceptibilityor reducing exposure for
J J J J J J J J J J J J J
susceptible individuals, in this case by providing vaccination. Secondary prevention is the early
J J J J J J J J J J J J J
detection, screening, and management of the disease. Tertiary prevention includes rehabilitative
J J J J J J J J J J J
and supportive care and attempts to alleviate disability and restore effective functioning. Disease
J J J J J J J J J J J J J
treatment involves management of the disease once it has developed.
J J J J J J J J J
3. An obese but otherwise healthy teen is given a prescription for a low-calorie diet and exercise
J J J J J J J J J J J J J J J J
program. This is an example of J J J J J
a. primary prevention. J
b. secondary prevention. J
c. tertiaryprevention. J
d. disease treatment. J
ANS: B J
Secondaryprevention is the earlydetection, screening, and management of the disease such as
J J J J J J J J J J J J J J
prescribing diet and exercise for an individual who has already developed obesity. Primary
J J J J J J J J J J J J J
prevention is prevention of disease by altering susceptibility or reducing exposure for susceptible
J J J J J J J J J J J J J
individuals. Tertiary prevention includes rehabilitative and supportive care and attempts to
J J J J J J J J J J J
alleviate disability and restore effective functioning. Disease treatment involves management of
J J J J J J J J J J J
the disease once it has developed.
J J J J J
,4. A patient with high blood pressure who is otherwise healthy is counseled to restrict sodium
J J J J J J J J J J J J J J J
intake. This is an example ofJ J J J J
a. primary prevention. J
b. secondary prevention. J
c. tertiaryprevention. J
d. disease treatment. J
ANS: B J
Secondary prevention is the early detection, screening, and management of the disease, such as by
J J J J J J J J J J J J J J J
prescribing sodium restriction for high blood pressure. Primary prevention is prevention of disease
J J J J J J J J J J J J J
by altering susceptibility or reducing exposure for susceptible individuals. Tertiary prevention
J J J J J J J J J J J
includes rehabilitative and supportive care and attempts to alleviate disability and restore
J J J J J J J J J J J J
effective functioning. Disease treatment involves management of the disease once it has
J J J J J J J J J J J J
developed.
5. After suffering a heart attack, a middle-aged man is counseled to take a cholesterol-lowering
J J J J J J J J J J J J J J
medication. This is an example of J J J J J
a. primary prevention. J
b. secondary prevention. J
c. tertiaryprevention. J
d. disease treatment. J
ANS: C J
Tertiary prevention includes rehabilitative and supportive care and attempts to alleviate disability
J J J J J J J J J J J J
and restore effective functioning such as prescribing a cholesterol-lowering medication following
J J J J J J J J J J J
a heart attack. Primary prevention is prevention of disease by altering susceptibility or reducing
J J J J J J J J J J J J J J
exposure for susceptible individuals. Secondary prevention is the early detection, screening, and
J J J J J J J J J J J J
management of the disease. Disease treatment involves management of the disease once it has J J J J J J J J J J J J J J
developed.
6. A patient has been exposed to meningococcal meningitis, but is not yet demonstrating signs of this
J J J J J J J J J J J J J J J J
disease. This stage of illness is called the
J J J J J J J stage.
a. prodromal
b. latent
c. sequela
d. convalescence
ANS: B J
Incubation refers to the interval between exposure of a tissue to an injurious agent and the first
J J J J J J J J J J J J J J J J J
appearance of signs and symptoms. In infectious diseases, this period is often called the incubation
J J J J J J J J J J J J J J J
(latent) period. Prodromal refers to the appearance of the first signs and symptoms indicating the
J J J J J J J J J J J J J J J
onset of a disease. These are often nonspecific, such as headache, malaise, anorexia, and nausea,
J J J J J J J J J J J J J J J
which are associated with a number of different diseases. Sequela refers to subsequent pathologic
J J J J J J J J J J J J J J
condition resulting from a disease. Convalescence is the stage of recovery after a disease, injury, or
J J J J J J J J J J J J J J J J
surgical operation. J
7. A disease that is native to a particular region is called
J J J J J J J J J J
a. epidemic.
b. endemic.
c. pandemic.
d. ethnographic.
, ANS: B J
A disease that is native to a particular region is called endemic. An epidemic is a disease that spreads
J J J J J J J J J J J J J J J J J J J
to many individuals at the same time. Pandemics are epidemics that affect large geographic regions,
J J J J J J J J J J J J J J J
perhaps spreading worldwide. Ethnographic does not describe a disease distribution pattern.
J J J J J J J J J J
8. In general, with aging, organ size and function
J J J J J J J
a. increase.
b. decrease.
c. remain the same. J J
d. are unknown. J
ANS: B J
In general, with aging, organ size and function decrease.
J J J J J J J J
9. The stage during which the patient functions normally, although the disease processes are well
J J J J J J J J J J J J J J
established, is referred to as J J J J
a. latent.
b. subclinical.
c. prodromal.
d. convalescence.
ANS: B J
The stage during which the patient functions normally, although the disease processes are well
J J J J J J J J J J J J J J
established, is called the subclinical stage. The interval between exposure of a tissue to an injurious
J J J J J J J J J J J J J J J J
agent and the first appearance of signs and symptoms may be called a latent period or, in the case of
J J J J J J J J J J J J J J J J J J J J
infectious diseases, an incubation period. The prodromal period, or prodrome, refers to the
J J J J J J J J J J J J J
appearance of the first signs and symptoms indicating the onset of a disease. Convalescence is the
J J J J J J J J J J J J J J J J
stage of recovery after a disease, injury, or surgical operation.
J J J J J J J J J
MULTIPLE RESPONSE J
1. Your patient’s red blood cell count is slightly elevated today. This might be explained by
J J J J J J J J J J J J J J J
(Select all that apply.) J J J
a. gender difference. J
b. situational factors. J
c. normal variation. J
d. cultural variation. J
e. illness.
ANS: A, B, C, E
J J J J
Gender, situations (e.g., altitude), normal variations, and illness mayall determine red blood cell
J J J J J J J J J J J J J J
count. Culture affects how manifestations are perceived (normal versus abnormal).
J J J J J J J J J
2. Socioeconomic factors influence disease development because of (Select all that apply.) J J J J J J J J J J
a. genetics.
b. environmental toxins. J
c. overcrowding.
d. nutrition.
e. hygiene.
, ANS: B, C, D, E J J J J
Socioeconomic factors influence disease development via exposure to environmental toxins J J J J J J J J J J
(occupational) and overcrowding, nutrition (over- or undernutrition), and hygiene (e.g., in J J J J J J J J J J J
developing countries). Genetics is not influenced by socioeconomic factors.
J J J J J J J J
3. When determining additional data to gather before making a diagnosis, what factors need to be
J J J J J J J J J J J J J J J
considered? (Select all that apply.) J J J J
a. Reliability
b. Expense
c. Validity
d. Generalizability
e. Repetition
ANS: A, C J J
Two considerations one must use when choosing additional data to gather include the reliability
J J J J J J J J J J J J J J
and validity of the tests being weighed. Reliability, or precision, is the ability of a test to give the
J J J J J J J J J J J J J J J J J J J
same result in repeated measurements. Validity, or accuracy, is the degree to which a
J J J J J J J J J J J J J J
measurement reflects the true value of the object it is intended to measure. Expense, J J J J J J J J J J J J J J
generalizability, and repetition are not characteristics that are typically considered. J J J J J J J J J
4. Which of the following statements are accurate when considering diagnostic testing for an
J J J J J J J J J J J J J
individual with a possible medical condition? (Select all that apply.)
J J J J J J J J J
a. The more often a patient has a test, the more accurate the average result is.
J J J J J J J J J J J J J J
b. Sensitivity is the chance the test will be positive if the hypothesized disease is J J J J J J J J J J J J J J
present.
c. Testing is generally not accurate during the prodromal stage to make a diagnosis.
J J J J J J J J J J J J
d. Specificity shows that a test will be negative if the person does not have the J J J J J J J J J J J J J J J
disease.
e. Reliabilitydemonstrates a test is accurate under a number of different conditions. J J J J J J J J J J J
ANS: B, D J J
Sensitivity is the probability that the test will be positive when applied to a person with the
J J J J J J J J J J J J J J J J J
condition. Specificity is the probability that a test will be negative when applied to a person who
J J J J J J J J J J J J J J J J J
does not have a given condition. Test results are usuallynot aggregated and averaged. A disease
J J J J J J J J J J J J J J J J
process is well established during the prodromal phase of illness, so some diagnostic testing would
J J J J J J J J J J J J J J J
indicate its presence. Reliability, or precision, is the ability of a test to give the same result in
J J J J J J J J J J J J J J J J J J
repeated measurements. J
Chapter 02: Homeostasis, Allostasis, and Adaptive Responses to Stressors
J J J J J J J J J
Banasik: Pathophysiology, 7th Edition
J J J
MULTIPLE CHOICE J
1. Indicators that an individual is experiencing high stress include all the following except
J J J J J J J J J J J J
a. tachycardia.
b. diaphoresis.
c. increased peripheral resistance. J J
d. pupil constriction. J
ANS: D J