NSG552 Psychopharmacology Exam 1
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, What are the 6 general principles of psychopharmacological treatment? - correct ans:Safety
Tolerability
Efficacy
Practicality
Treatment accessibility
Treatment compliance
Pharmacokinetics - correct ans:How the drug moves in the body. (ex. Where is it absorbed? How and
where is it metabolized? Where is it excreted?)
Pharmacodynamics - correct ans:What the drug does to the body. (consider mechanism of action)
Define First-generation antipsychotics - correct ans:Referred to as Typical Antipsychotics. Most have
strong bond with D2 receptors only, cause EPS symptoms faster due to prolonged receptor dissociation,
have more dangerous side effect profiles, have been around longer, more effective at treating positive
symptoms, less expensive. (Ex. Haloperidol, Chlorpromazine, Thioridazine, Fluphenazine)
Define Second-generation antipsychotics - correct ans:Referred to as Atypical Antipsychotics. Most have
a weak bond with D2 receptors and block serotonin receptors leading to anti-depressive and anxiolytic
effects. They cause less EPS due to rapid receptor disassociation which leads to rapid dopamine
neurotransmission. Have less dangerous side effect profiles but can cause metabolic syndromes, have
been around shorter time, more expensive, more effective at treating negative symptoms but can treat
positive symptoms as well, long-acting injections available for several of these. (Ex. Risperidone,
Clozapine, Quetiapine, Aripiprazole, Ziprasidone)
Extra Pyramidal Symptoms (EPS) - correct ans:Side effects caused by certain antipsychotic medications,
which include: involuntary or uncontrollable movements. tremors. muscle contractions.
Tardive dyskinesia - correct ans:A neurological disorder characterize by involuntary movement of the
face and jaw.
Upregulation - correct ans:Occurs through chronic use of antagonists which causes an increase in the
number of receptors, externalization of receptors, and increased sensitivity of the receptors. Prolonged
use of antagonist -> Up-regulation of receptors -> Sudden withdrawal of antagonist -> increased number
PROCTORED LATEST VERIFIED
VERSION OF {2026-2027} With
Expected real and comprehensive
Questions With Well Elaborated
Correct Answers GRADED A+
Professional Academic Assistance Services
Services Offered
Proctored Exam Assistance
Online Class Management (Full Course Support)
Exam Preparation & Study Materials
Assignments and Coursework Support
Essays and Research Papers
Discussion Posts and Replies
, What are the 6 general principles of psychopharmacological treatment? - correct ans:Safety
Tolerability
Efficacy
Practicality
Treatment accessibility
Treatment compliance
Pharmacokinetics - correct ans:How the drug moves in the body. (ex. Where is it absorbed? How and
where is it metabolized? Where is it excreted?)
Pharmacodynamics - correct ans:What the drug does to the body. (consider mechanism of action)
Define First-generation antipsychotics - correct ans:Referred to as Typical Antipsychotics. Most have
strong bond with D2 receptors only, cause EPS symptoms faster due to prolonged receptor dissociation,
have more dangerous side effect profiles, have been around longer, more effective at treating positive
symptoms, less expensive. (Ex. Haloperidol, Chlorpromazine, Thioridazine, Fluphenazine)
Define Second-generation antipsychotics - correct ans:Referred to as Atypical Antipsychotics. Most have
a weak bond with D2 receptors and block serotonin receptors leading to anti-depressive and anxiolytic
effects. They cause less EPS due to rapid receptor disassociation which leads to rapid dopamine
neurotransmission. Have less dangerous side effect profiles but can cause metabolic syndromes, have
been around shorter time, more expensive, more effective at treating negative symptoms but can treat
positive symptoms as well, long-acting injections available for several of these. (Ex. Risperidone,
Clozapine, Quetiapine, Aripiprazole, Ziprasidone)
Extra Pyramidal Symptoms (EPS) - correct ans:Side effects caused by certain antipsychotic medications,
which include: involuntary or uncontrollable movements. tremors. muscle contractions.
Tardive dyskinesia - correct ans:A neurological disorder characterize by involuntary movement of the
face and jaw.
Upregulation - correct ans:Occurs through chronic use of antagonists which causes an increase in the
number of receptors, externalization of receptors, and increased sensitivity of the receptors. Prolonged
use of antagonist -> Up-regulation of receptors -> Sudden withdrawal of antagonist -> increased number
