MICROBIOLOGY EXAM 4 PRACTICE QUESTIONS AND
ANSWERS
All of the following are generally used in vaccines EXCEPT...
a. toxoids
b. parts of bacterial cells
c. live, attenuated viruses
d. inactivated viruses
e. antibodies - Answers - e. antibodies
A reaction between an antibody and soluble antigen-forming lattices is called a(n)...
a. agglutination reaction
b. complement fixation
c. immunofluorescence
d. neutralization reaction
e. precipitation reaction. - Answers - e. precipitation reaction
A DNA plasmid encoding a protein antigen from West Nile virus is injected into muscle
cells of a horse. This is an example of a(n)...
a. subunit vaccine
b. conjugated vaccine
c. DNA vaccine
d. attenuated whole-agent vaccine
e. live whole-agent vaccine. - Answers - c. DNA vaccine
What type of vaccine is the live, weakened measles virus?
a. conjugated vaccine
b. subunit vaccine
c. nucleic acid vaccine
d. attenuated whole-agent vaccine
e. toxoid vaccine - Answers - d. attenuated whole-agent vaccine
Which item is a direct ELISA test screening for?
a. substrate for the enzyme
b. antigen
c. antihuman immune serum
, d. antibodies against the antigen - Answers - b. antigen
Which of the following tests is MOST useful in determining the presence of AIDS
antibodies?
a. agglutination
b. complement fixation
c. neutralization
d. indirect ELISA
e. direct fluorescent-antibody - Answers - d. indirect ELISA
Which of the following is NOT an advantage of live attenuated vaccine agents?
a. They elicit lifelong immunity
b. They stimulate by cell-mediated and humoral immune responses
c. They never revert to virulent forms
d. They require few or no booster immunizations
e. The immune response generated by the vaccine closely mimics a real infection. -
Answers - c. they never revert to virulent forms
In order to view Treponema pallidum, the causative agent of syphilis, under the
microscope, you can tag the specimen with an antibody-flourescein dye complex and
look under a microscope that projects UV light onto the specimen. What test are you
using?
a. Western blot test
b. Fluorescence antibody (FA) test
c. Kirby-Bauer disc diffusion test
d. ELISA test
e. Agglutination test - Answers - b. fluorescence antibody (FA) test
Which of the following immunodiagnostic tests uses antibody or antigen attached to
latex beads?
a. Direct agglutination test
b. Indirect fluorescence antibody (FA) test
c. Indirect ELISA test
d. Direct ELISA test
e. Passive (indirect) agglutination test - Answers - e. passive (indirect) agglutination test
Diseases that primarily exist in animals, but may be transmitted to humans are called...
a. Helminthic
b. Zoonotic
c. Symbiotic
d. Epidemic
ANSWERS
All of the following are generally used in vaccines EXCEPT...
a. toxoids
b. parts of bacterial cells
c. live, attenuated viruses
d. inactivated viruses
e. antibodies - Answers - e. antibodies
A reaction between an antibody and soluble antigen-forming lattices is called a(n)...
a. agglutination reaction
b. complement fixation
c. immunofluorescence
d. neutralization reaction
e. precipitation reaction. - Answers - e. precipitation reaction
A DNA plasmid encoding a protein antigen from West Nile virus is injected into muscle
cells of a horse. This is an example of a(n)...
a. subunit vaccine
b. conjugated vaccine
c. DNA vaccine
d. attenuated whole-agent vaccine
e. live whole-agent vaccine. - Answers - c. DNA vaccine
What type of vaccine is the live, weakened measles virus?
a. conjugated vaccine
b. subunit vaccine
c. nucleic acid vaccine
d. attenuated whole-agent vaccine
e. toxoid vaccine - Answers - d. attenuated whole-agent vaccine
Which item is a direct ELISA test screening for?
a. substrate for the enzyme
b. antigen
c. antihuman immune serum
, d. antibodies against the antigen - Answers - b. antigen
Which of the following tests is MOST useful in determining the presence of AIDS
antibodies?
a. agglutination
b. complement fixation
c. neutralization
d. indirect ELISA
e. direct fluorescent-antibody - Answers - d. indirect ELISA
Which of the following is NOT an advantage of live attenuated vaccine agents?
a. They elicit lifelong immunity
b. They stimulate by cell-mediated and humoral immune responses
c. They never revert to virulent forms
d. They require few or no booster immunizations
e. The immune response generated by the vaccine closely mimics a real infection. -
Answers - c. they never revert to virulent forms
In order to view Treponema pallidum, the causative agent of syphilis, under the
microscope, you can tag the specimen with an antibody-flourescein dye complex and
look under a microscope that projects UV light onto the specimen. What test are you
using?
a. Western blot test
b. Fluorescence antibody (FA) test
c. Kirby-Bauer disc diffusion test
d. ELISA test
e. Agglutination test - Answers - b. fluorescence antibody (FA) test
Which of the following immunodiagnostic tests uses antibody or antigen attached to
latex beads?
a. Direct agglutination test
b. Indirect fluorescence antibody (FA) test
c. Indirect ELISA test
d. Direct ELISA test
e. Passive (indirect) agglutination test - Answers - e. passive (indirect) agglutination test
Diseases that primarily exist in animals, but may be transmitted to humans are called...
a. Helminthic
b. Zoonotic
c. Symbiotic
d. Epidemic