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NUR 6130 Exam 2 | (2026) Advanced Practice Nursing III Questions & Answers | William Paterson University – Complete A+ Study Guide (PDF)

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Ace NUR 6130 Exam 2 (Advanced Practice Nursing III) at William Paterson University with this comprehensive 2026 test bank featuring actual exam questions, verified correct answers, and detailed rationales. Updated for the 2025/2026 academic year. Covers all Exam 2 blueprint topics including acute lymphoblastic leukemia (ALL, most common childhood cancer, peak incidence 2-5 years), myelogenous leukemia (CML, Philadelphia chromosome t(9;22) BCR-ABL1), solid tumors (neuroblastoma adrenal sympathetic chain), rhabdomyosarcoma (skeletal muscle children embryonal type), Ewing sarcoma (primitive neuroectodermal tumor), retinoblastoma (RB1 gene), osteosarcoma (second most common primary bone cancer, femur metaphysis), renal disorders (nephrotic syndrome hyperlipidemia, glomerulonephritis poststreptococcal, hydronephrosis calyceal dilation), fluid and electrolyte balance (infant TBW 75%, elderly prone to dehydration decreased thirst sensation, healthy adult I&O mL daily, osmoreceptors antidiuretic hormone ADH, atrial natriuretic peptide ANP sodium excretion), acid-base disorders (pH 7.35-7.45, respiratory alkalosis hyperventilation, metabolic alkalosis vomiting, anion gap calculation, Winter's formula for respiratory compensation pCO2=1.5[HCO3]+8±2), gastrointestinal disorders (Meckel diverticulum true diverticulum omphalomesenteric duct, Hirschsprung disease aganglionic megacolon, biliary atresia TORCH infection liver transplantation, intussusception currant jelly stool, colic crying 3 hours/day 3 days/week 3 weeks, UGI bleed melena hematemesis, lower GI bleeding hematochezia Meckel's scan technetium-99m), metabolic disorders (phenylketonuria PKU hypotonia seizures, galactosemia Escherichia coli sepsis mental retardation, congenital adrenal hyperplasia 21-hydroxylase deficiency hyponatremia hyperkalemia vomiting ambiguous genitalia), respiratory disorders (cystic fibrosis CFTR gene mutation F508del, primary ciliary dyskinesia Kartagener syndrome situs inversus, tracheomalacia extrathoracic collapse inspiration), and test-taking strategies prioritization Maslow safety ABCs. Includes 50+ high-yield practice questions with rationales. Perfect for graduate nursing and NP students – graded A+.

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NUR 6130
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1

, NUR 6130 Exam 2 | (2026) Nursing Exam

Questions | Practice III (PDF)

1. A 58-year-old male with chronic alcoholism presents

with confusion, ataxia, and nystagmus. Thiamine is

administered immediately. Which condition is being

treated?

A. Wernicke encephalopathy

B. Korsakoff syndrome

C. Hepatic encephalopathy

D. Cerebellar degeneration

Answer: A

Rationale: Wernicke encephalopathy (confusion, ataxia,

nystagmus/ophthalmoplegia) is caused by thiamine

deficiency, common in alcoholism. Thiamine must be given

before glucose to prevent exacerbation.

2. In diabetic ketoacidosis (DKA), the primary cause of

the anion gap metabolic acidosis is:

A. Lactic acidosis


2

,B. Hyperchloremia

C. Accumulation of ketone bodies (β -hydroxybutyrate,

acetoacetate)

D. Renal failure

Answer: C

Rationale: Insulin deficiency leads to lipolysis and

ketogenesis, producing ketoacids that consume

bicarbonate and widen the anion gap.

3. A patient with chronic kidney disease (stage 4)

develops hyperphosphatemia. This directly leads to:

A. Hypocalcemia

B. Hypercalcemia

C. Metabolic alkalosis

D. Hypermagnesemia

Answer: A

Rationale: Hyperphosphatemia binds with serum calcium,

lowering ionized calcium, which triggers secondary

hyperparathyroidism.

3

, 4. Which cytokine is primarily responsible for cachexia in
k k k k k k k




k chronic heart failure and cancer?
k k k k




A. IL-10

B. TNF-α

C. IL-4

D. IFN-γ

Answer: B k




Rationale: TNF-α promotes lipolysis, muscle wasting, and
k k k k k




k anorexia, leading to cachexia.
k k k




5. A patient with prolonged QT interval develops torsade de
k k k k k k k k




k pointes. Which electrolyte imbalance is most likely?
k k k k k k




A. Hyperkalemia

B. Hypomagnesemia

C. Hypercalcemia

D. Hyponatremia

Answer: B
k k




Rationale: Hypomagnesemia prolongs repolarization,
k k k




4

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