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BIO 669 Exam 2 – BIO 669 – Complete Cardiovascular and Endocrine Systems Exam Questions and Answers (June 2026)

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This document contains a comprehensive set of BIO 669 Exam 2 multiple-choice questions with answers covering cardiovascular and endocrine pathophysiology. Topics include cardiac physiology, hypertension, myocardial infarction, vascular disorders, endocrine hormone regulation, diabetes mellitus, thyroid disorders, pituitary function, adrenal disorders, and calcium homeostasis. The material is presented in exam-preparation format with answer keys and covers a broad range of concepts commonly tested in advanced pathophysiology courses.

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Institution
BIO 669
Course
BIO 669

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BIO 669 Exam 2 c. A decrease in aortic compliance
June 2023 Milo0420 increases its stiffness and thus can lead
to an increase in pulse pressures
Thromboangiitis obliterans (Buergers
disease) is an autoimmune condition d. Prostacyclins, which are diminished
that is: by NSAIDs, are vasoconstrictors.
d. Prostacyclins, which are diminished by
a. A result of over activation of the NSAIDS, are vasoconstrictors
intrinsic and extrinsic clotting system Which of the following is incorrect
systemically regarding the isometric contraction
phase of the cardiac cycle?
b. Characterized by attacks of
vasospasm in the small arteries and a. Blood does not flow through the heart
arterioles of the fingers and toes at this time.

c. Strongly associated with smoking b. The atria are contracting

d. Associated with janeway lesions and c. The valves are closed
Oslers Nodes
c. Strongly associated with smoking d. It occurs during ventricular systole
Which of the following is not a systemic b. The atria are contracting
disease that is associated with The resistance of movement of blood
Raynaud's Phenomenon? from the left ventricle to the aorta is
termed the:
a. Congestive heart failure
a. Ejection fraction
b. Collagen vascular diseases such as
scleroderma b. Compliance

c. Pulmonary hypertension c. Preload

d. Myxedema or smoking d. Afterload
a. Congestive Heart Failure d. Afterload
Which of the following is NOT a primary Natriuretic peptides act by:
factor in determining preload?
a. Stimulates secretion of Na+ (and thus
a. Venous return during diastole decreases urine volume) from the
kidneys
b. End systolic volume
b. Stimulated the release of Na+ (thus
c. Total peripheral (systemic) resistance increases urine volume) from the
kidneys
d. All of the above are primary factors of
preload c. Increases vascular smooth muscle
c. Total peripheral (systemic) resistance contraction (vasoconstriction)
Which of the following statements are
INCORRECT d. Stimulates increased heart rate,
contractility, and cardiac output
a. The mean arterial pressure is the b. Stimulate the release of Na+ (thus
average force of pushing blood through increasing urine volume) from the kidneys
the systemic circuit. The double layered serous membrane
surrounding the heart that functions to
b. The pulse pressure is the difference minimize friction from the heart
between systolic and diastolic pressures movement is the:

,A. Myocardium
D. Aneurysm
B. Endocardium B. Complicated plaque
The PR Interval represents the time
C. Peritoneum from:

D. Pericardium A. The onset of atrial systole to the
D. Pericardium completion of atrial diastole
Prinzmetal angina is:
B. The onset of atrial systole to the
a. A transient ischemia of the onset of ventricular diastole
myocardium that occurs unpredictably
C. The onset of atrial systole to the
b. Myocardial ischemia that may not onset of ventricular diastole
cause detectable symptoms
D. The onset of atrial systole to the
c. Ischemia that occurs after a onset of ventricular systole
predictable amount of exercise D. The onset of atrial systole to the onset of
ventricular systole
d. The rupture of an unstable plaque The circumflex artery off of the left
a. A transient ischemia of the myocardium coronary artery:
that occurs unpredictably
Progressive venous distension of the A. Left atrium and ventricle
head and upper extremities resulting
from growth of a cancerous tumor on B. The two atria
the right mainstem bronchus is best
described clinically by: C. The two ventricles

A. Deep vein thrombosis D. The aorta and the pulmonary artery
A. Left atrium and ventricle
B. Spinal shock The structures that connect the
leaflets/cusps and help to prevent
C. Superior vena cava syndrome prolapse of the AV valves is the:

D. Carcinoid syndrome A. Chordae tendineae and papillary
C. Superior Vena Cava Syndrome muscles
The most common cause of aneurysm is:
B. Cardiomyocytes
A. External Hematoma
C. Interventricular septum
B. Atherosclerosis with hypertension
D. Coronary ostia
C. Genetics A. Chordae tendineae and papillary muscles
Hypertensive crisis (malignant
D. Congestive heart failure hypertension) is best defined as:
B. Atherosclerosis with hypertension
An atherosclerotic area that has A. An advancing failure of systemic
ruptured is termed a: circulation as the heart weakens

A. Fibrous plaque B. Rapidly progressive hypertension
with a diastolic pressure of 140 mmHg
B. Complicated plaque or more

C. Fatty streak C. A pulse pressure of greater than 60

, D. Blood pressure readings consistently
greater than 140/90 mmHg B. ATP
B. Rapidly progressive hypertension with a
diastolic pressure of 140 mmHg or more C. K+
Intermittent claudication is:
D. Epinephrine
A. Caused by coronary artery disease A. Ca++
Myocardial hibernation is best
B. A sign of peripheral artery disease described as:

C. An attack of vasospasm brought on by A. Myocardial cells that are persistently
the cold ischemic and undergo metabolic
adaptation to prolong survival
D. A result of peripheral neuropathy
B. A sign of peripheral artery disease B. Hypertrophy that occurs with loss of
Stroke volume: contractile function

A. Does not affect the cardiac index C. Temporary loss of contractile
function that persists for hours to days
B. Is equal to ESV - EDV after restoration of perfusion

C. Does not vary much D. Fibroblast proliferation and severe
inflammatory response
D. None of the above are true A. Myocardial cells that are persistently
D. None of the above are true ischemic and undergo metabolic adaptation
A T wave relates to ______ and shortly to prolong survival
precedes the closure of the _____ valves. A thrombus is a blood clot that remains
attached to a vessel wall. Which of the
A. Ventricular depolarization, AV following is NOT one of the main factors
as proposed by Virchow?
B. Ventricular depolarization, SL
A. Obesity
C. Ventricular repolarization, AV
B. Venous Stasis
D. Ventricular repolarization, SL
C. Venous Endothelial damage
E. None of the above
D. Ventricular repolarization, SL D. Hypercoagulable states
How much of the oxygen carried by A. Obesity
hemoglobin in the blood is actually The decreased or instability to generate
transferred to the myocardium? action potential due to
hyperpolarization or continued closure
A. 10-20% of inactivation gates is termed:

B. 40-50% A. Rhythmicity

C. 70-75% B. Quiescence

D. 100% C. Refractory period
C. 70-75%
The key regulator determining if a D. Afterload
muscle, such as cardiac muscle, C. Refractory period
contracts or not is the presence of: All of the following antihypertensive
agents would be appropriate first line
A. Ca++ treatments EXCEPT:

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