BSN Safety and Infection Control for NCLEX-RN 2026/2027 UPDATE
1. When caring for a patient with Clostridioides difficile (C. diff), which hand
hygiene method is mandatory?
A. Alcohol-based hand rub
B. Using iodine-based solution
C. Washing with soap and water
D. Wearing gloves without washing
Answer: C
Rationale: Alcohol-based rubs are ineffective against C. diff spores; physical scrubbing
with soap and water is required to mechanically remove them.
2. Which personal protective equipment (PPE) is required when entering a room
for a patient on Droplet Precautions?
A. N95 respirator
B. Surgical mask
C. Gown and gloves only
D. Face shield and shoe covers
Answer: B
Rationale: Droplet precautions require a standard surgical mask when within 3 to 6 feet of
the patient.
,3. A nurse is preparing to care for a patient with Tuberculosis. Which room
assignment is most appropriate?
A. Private room with negative pressure ventilation
B. Private room with positive pressure ventilation
C. Semiprivate room with a patient who has pneumonia
D. Standard private room with the door kept open
Answer: A
Rationale: Tuberculosis requires Airborne Precautions, which includes an Airborne
Infection Isolation Room (AIIR) with negative pressure.
4. What is the first action a nurse should take after experiencing a needlestick
injury?
A. Report the incident to the supervisor
B. Complete an incident report
C. Wash the site with soap and water
D. Go to the emergency department for prophylaxis
Answer: C
Rationale: Immediate first aid, such as washing the area with soap and water, is the
priority before reporting or documentation.
5. According to the ‘Six Rights’ of medication administration, which of the
following is correct?
A. Right Patient, Right Medication, Right Dose, Right Route, Right Time, Right Documentation
B. Right Patient, Right Room, Right Dose, Right Route, Right Time, Right Documentation
C. Right Patient, Right Medication, Right Frequency, Right Route, Right Time, Right Physician
D. Right Patient, Right Medication, Right Dose, Right Pharmacy, Right Time, Right Documentation
Answer: A
Rationale: The standard six rights are: Patient, Medication, Dose, Route, Time, and
Documentation.
, 6. Which patient is at the highest risk for falls?
A. A 50-year-old postoperative patient who is alert and oriented
B. A 75-year-old patient with a history of falls and orthostatic hypotension
C. A 30-year-old patient with a fractured arm
D. A 60-year-old patient receiving IV fluids
Answer: B
Rationale: Advanced age, history of falls, and physiological factors like orthostatic
hypotension significantly increase fall risk.
7. In which order should PPE be removed (doffing) to minimize contamination?
A. Gown, Mask, Goggles, Gloves
B. Mask, Gown, Gloves, Goggles
C. Gloves, Goggles, Gown, Mask
D. Goggles, Gloves, Mask, Gown
Answer: C
Rationale: The standard sequence for doffing is gloves, goggles/face shield, gown, and
finally the mask/respirator.
8. A healthcare provider orders wrist restraints for a confused patient. How
often must the nurse assess the patient’s skin integrity and circulation?
A. Every 30 minutes
B. Every 4 hours
C. Every 2 hours
D. Once per shift
Answer: C
Rationale: Patients in restraints must be assessed at least every 2 hours for skin integrity,
neurovascular status, and the need for continued restraint.
1. When caring for a patient with Clostridioides difficile (C. diff), which hand
hygiene method is mandatory?
A. Alcohol-based hand rub
B. Using iodine-based solution
C. Washing with soap and water
D. Wearing gloves without washing
Answer: C
Rationale: Alcohol-based rubs are ineffective against C. diff spores; physical scrubbing
with soap and water is required to mechanically remove them.
2. Which personal protective equipment (PPE) is required when entering a room
for a patient on Droplet Precautions?
A. N95 respirator
B. Surgical mask
C. Gown and gloves only
D. Face shield and shoe covers
Answer: B
Rationale: Droplet precautions require a standard surgical mask when within 3 to 6 feet of
the patient.
,3. A nurse is preparing to care for a patient with Tuberculosis. Which room
assignment is most appropriate?
A. Private room with negative pressure ventilation
B. Private room with positive pressure ventilation
C. Semiprivate room with a patient who has pneumonia
D. Standard private room with the door kept open
Answer: A
Rationale: Tuberculosis requires Airborne Precautions, which includes an Airborne
Infection Isolation Room (AIIR) with negative pressure.
4. What is the first action a nurse should take after experiencing a needlestick
injury?
A. Report the incident to the supervisor
B. Complete an incident report
C. Wash the site with soap and water
D. Go to the emergency department for prophylaxis
Answer: C
Rationale: Immediate first aid, such as washing the area with soap and water, is the
priority before reporting or documentation.
5. According to the ‘Six Rights’ of medication administration, which of the
following is correct?
A. Right Patient, Right Medication, Right Dose, Right Route, Right Time, Right Documentation
B. Right Patient, Right Room, Right Dose, Right Route, Right Time, Right Documentation
C. Right Patient, Right Medication, Right Frequency, Right Route, Right Time, Right Physician
D. Right Patient, Right Medication, Right Dose, Right Pharmacy, Right Time, Right Documentation
Answer: A
Rationale: The standard six rights are: Patient, Medication, Dose, Route, Time, and
Documentation.
, 6. Which patient is at the highest risk for falls?
A. A 50-year-old postoperative patient who is alert and oriented
B. A 75-year-old patient with a history of falls and orthostatic hypotension
C. A 30-year-old patient with a fractured arm
D. A 60-year-old patient receiving IV fluids
Answer: B
Rationale: Advanced age, history of falls, and physiological factors like orthostatic
hypotension significantly increase fall risk.
7. In which order should PPE be removed (doffing) to minimize contamination?
A. Gown, Mask, Goggles, Gloves
B. Mask, Gown, Gloves, Goggles
C. Gloves, Goggles, Gown, Mask
D. Goggles, Gloves, Mask, Gown
Answer: C
Rationale: The standard sequence for doffing is gloves, goggles/face shield, gown, and
finally the mask/respirator.
8. A healthcare provider orders wrist restraints for a confused patient. How
often must the nurse assess the patient’s skin integrity and circulation?
A. Every 30 minutes
B. Every 4 hours
C. Every 2 hours
D. Once per shift
Answer: C
Rationale: Patients in restraints must be assessed at least every 2 hours for skin integrity,
neurovascular status, and the need for continued restraint.