1
, WGU D027 ADVANCED
PATHOPHARMACOLOGICAL
FOUNDATIONS QUESTIONS AND
VERIFIED ANSWERS
A 23 - year - old woman comes in for prenatal counseling. While completing
her family history, she reports her brother has cystic fibrosis. She does
not know if she is a carrier. She asks if her children will be affected by the
disease.
What is an accurate way to determine the likelihood of this patient's children
being affected?
A sweat test
A genetic or a carrier test
A history and a physical
A fertility test - ANSWER - A genetic or carrier test
The disease occurs when an individual inherits the mutated gene from
each parent. When only one mutated gene is inherited, the individual is
labeled a carrier.
chance of the disease.
2
,A 31- year - old man comes into the office for an exam. He is 6' 5 " with a
high - pitched voice, and he has a moderate degree of mental impairment.
It is discovered upon exam that his body hair is sparse, his testes are
small, and he has gynecomastia.
Which genetic disorder should this patient be tested for?
Klinefelter syndrome
Turner syndrome
Partial trisomy
Sex chromosome aneuploidy - ANSWER - Klinefelter syndrome: a
hereditary disease also known as 47,XXY or XXY that manifests as the
series of symptoms described.
A six - month - old female infant with failure to thrive comes in to the office
with her parents. It is noticed upon exam that the patient has facial
deformities and is jaundiced. A complete blood count (CBC) is ordered,
which reveals anemia. When that patient's blood is examined under a
microscope, the red blood cells appear small and abn ormally shaped. A
mutational analysis is ordered, and alpha thalassemia is diagnosed.
What is the likelihood of incidence of these parent's future children having
alpha thalassemia?
25%
100%
0%
50% - ANSWER - 25% or 1/4 chance
3
, A 64 - year - old male truck driver comes in complaining of pain in his lower
left calf. He states he drives eight to ten hours per day. Upon exam, swelling
and mottled coloring are noted in the patient's calf. A D - dimer test is
ordered and comes back positive.
Which additional test should be ordered to confirm a diagnosis in this
patient?
A CT scan
A Doppler Ultrasound
The D - dimer test again
A clotting factors test - ANSWER - A Doppler Ultrasound is the initial test
of choice for patients who are not initially stratified according to clinical
pretest probability (PTP) as being low, moderate, or high risk for DVT.
A 54 - year - old man comes into a clinic for a routine visit. His initial BP is
148/92. After a recheck 15 minutes later, his BP is 140/90. He states he
suffers from "white coat hypertension." He states he has no history of high
blood pressure and no family h istory of high blood pressure.
Which nursing intervention would assist this patient in receiving a clinical
diagnosis of hypertension?
Ordering the patient a cholesterol level test
Checking the patient's blood pressure in three months
Completing a biochemical blood profile
Completing an ambulatory blood pressure assessment - ANSWER -
Completing an ambulatory BP assessment.
Assessing blood pressure in a location of comfort like the home
environment when no professional is present will enable the ability to
determine his blood pressure under routine circumstances.
4
, WGU D027 ADVANCED
PATHOPHARMACOLOGICAL
FOUNDATIONS QUESTIONS AND
VERIFIED ANSWERS
A 23 - year - old woman comes in for prenatal counseling. While completing
her family history, she reports her brother has cystic fibrosis. She does
not know if she is a carrier. She asks if her children will be affected by the
disease.
What is an accurate way to determine the likelihood of this patient's children
being affected?
A sweat test
A genetic or a carrier test
A history and a physical
A fertility test - ANSWER - A genetic or carrier test
The disease occurs when an individual inherits the mutated gene from
each parent. When only one mutated gene is inherited, the individual is
labeled a carrier.
chance of the disease.
2
,A 31- year - old man comes into the office for an exam. He is 6' 5 " with a
high - pitched voice, and he has a moderate degree of mental impairment.
It is discovered upon exam that his body hair is sparse, his testes are
small, and he has gynecomastia.
Which genetic disorder should this patient be tested for?
Klinefelter syndrome
Turner syndrome
Partial trisomy
Sex chromosome aneuploidy - ANSWER - Klinefelter syndrome: a
hereditary disease also known as 47,XXY or XXY that manifests as the
series of symptoms described.
A six - month - old female infant with failure to thrive comes in to the office
with her parents. It is noticed upon exam that the patient has facial
deformities and is jaundiced. A complete blood count (CBC) is ordered,
which reveals anemia. When that patient's blood is examined under a
microscope, the red blood cells appear small and abn ormally shaped. A
mutational analysis is ordered, and alpha thalassemia is diagnosed.
What is the likelihood of incidence of these parent's future children having
alpha thalassemia?
25%
100%
0%
50% - ANSWER - 25% or 1/4 chance
3
, A 64 - year - old male truck driver comes in complaining of pain in his lower
left calf. He states he drives eight to ten hours per day. Upon exam, swelling
and mottled coloring are noted in the patient's calf. A D - dimer test is
ordered and comes back positive.
Which additional test should be ordered to confirm a diagnosis in this
patient?
A CT scan
A Doppler Ultrasound
The D - dimer test again
A clotting factors test - ANSWER - A Doppler Ultrasound is the initial test
of choice for patients who are not initially stratified according to clinical
pretest probability (PTP) as being low, moderate, or high risk for DVT.
A 54 - year - old man comes into a clinic for a routine visit. His initial BP is
148/92. After a recheck 15 minutes later, his BP is 140/90. He states he
suffers from "white coat hypertension." He states he has no history of high
blood pressure and no family h istory of high blood pressure.
Which nursing intervention would assist this patient in receiving a clinical
diagnosis of hypertension?
Ordering the patient a cholesterol level test
Checking the patient's blood pressure in three months
Completing a biochemical blood profile
Completing an ambulatory blood pressure assessment - ANSWER -
Completing an ambulatory BP assessment.
Assessing blood pressure in a location of comfort like the home
environment when no professional is present will enable the ability to
determine his blood pressure under routine circumstances.
4
