INFECTIOUS DISEASE TESTING AND
CULTURES - CTBS EXAM PRACTICE
2026 QUESTIONS AND ANSWERS
WITH COMPLETE SOLUTIONS
1. Diagnostic vs. Screening Tests
Question: Donor screening tests are used for almost all mandatory infectious
disease panels, except for which two sexually transmitted infections, which are
instead evaluated using diagnostic tests?
Answer: ✔✔ Chlamydia and Gonorrhea
2. HIV-1 Testing Requirements
Question: For all allogeneic tissue donations, what specific types of donor
screening assays are mandatory when testing for HIV-1?
Answer: ✔✔ Antibody testing and Nucleic Acid Testing (NAT)
3. HIV-2 Testing Requirements
Question: For all allogeneic tissue donations, what specific type of donor screening
assay is required when testing for HIV-2?
Answer: ✔✔ Antibody testing
4. Hepatitis B Testing Requirements
Question: For all allogeneic tissue donations, which three specific screening
markers must be tested to screen for the Hepatitis B virus (HBV)?
Answer: ✔✔ Hepatitis B Surface Antigen (HBsAg), Nucleic Acid Testing (NAT),
and total antibodies to Hepatitis B Core Antigen (Anti-HBc Total)
CULTURES - CTBS EXAM PRACTICE
2026 QUESTIONS AND ANSWERS
WITH COMPLETE SOLUTIONS
1. Diagnostic vs. Screening Tests
Question: Donor screening tests are used for almost all mandatory infectious
disease panels, except for which two sexually transmitted infections, which are
instead evaluated using diagnostic tests?
Answer: ✔✔ Chlamydia and Gonorrhea
2. HIV-1 Testing Requirements
Question: For all allogeneic tissue donations, what specific types of donor
screening assays are mandatory when testing for HIV-1?
Answer: ✔✔ Antibody testing and Nucleic Acid Testing (NAT)
3. HIV-2 Testing Requirements
Question: For all allogeneic tissue donations, what specific type of donor screening
assay is required when testing for HIV-2?
Answer: ✔✔ Antibody testing
4. Hepatitis B Testing Requirements
Question: For all allogeneic tissue donations, which three specific screening
markers must be tested to screen for the Hepatitis B virus (HBV)?
Answer: ✔✔ Hepatitis B Surface Antigen (HBsAg), Nucleic Acid Testing (NAT),
and total antibodies to Hepatitis B Core Antigen (Anti-HBc Total)