What are the nursing implications for Fludarabine?
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Monitor for visual changes and neurological changes
Infuse over 30 minutes for intermittent infusions, or over 24 hours for
continuous infusions
What are tubulin inhibitors derivatives of?
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Plant
,What do anthracyclines inhibit?
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topoisomerase II and prevent rejoining of the cleaved DNA strands.
What are the major side effects of corticosteroid?
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Hyperphagia, hyperglycemia, stomach/GI upset, gastritis
Immunosuppression
Personality changes, mood swings
Cushing syndrome, pituitary-adrenal axis suppression, hypertension
Poor wound healing, muscle weakness, osteonecrosis
What is the classification of arsenic trioxide?
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Miscellaneous
What is Hydroxyurea classified as?
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, Miscellaneous, cell-cycle-specific (S)
What are the major side effects of Mitoxantrone?
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Stomatitis/mucositis
Myelosuppression, immunosuppression
Green-blue discoloration of sclera, urine, and skin**
Elevated liver function tests
Cardiotoxicity, CHF, cardiac arrhythmias**
Phlebitis, severe tissue damage with extravasation**
What are the major side effects of Dacarbazine?
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Nausea, vomiting, anorexia
Flu-like symptoms (fever, malaise, body aches)
Liver dysfunction
Hypersensitivity reaction
Photosensitivity
how do alkylating and alkylating-like agents work?
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, They cause DNA strand breakage or uncoiling and interfere with DNA
replication, transcriptio; DNA strands unable to separate and uncoil and
divide
What are two exampels of Epipodophyllotoxins?
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-Etoposide
-Teniposide
What are the nursing implications for Fluorouracil (5-FU)?
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Administer oral doses on an empty stomach (1 hour pre-/2 hours post
meals); avoid acidic fruit juice
Monitor stool output
Monitor cardiac symptoms
Consider using cryotherapy to help reduce stomatitis/mucositis
What are the major side effects of Mitotane?
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Monitor for visual changes and neurological changes
Infuse over 30 minutes for intermittent infusions, or over 24 hours for
continuous infusions
What are tubulin inhibitors derivatives of?
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Plant
,What do anthracyclines inhibit?
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topoisomerase II and prevent rejoining of the cleaved DNA strands.
What are the major side effects of corticosteroid?
Give this one a try later!
Hyperphagia, hyperglycemia, stomach/GI upset, gastritis
Immunosuppression
Personality changes, mood swings
Cushing syndrome, pituitary-adrenal axis suppression, hypertension
Poor wound healing, muscle weakness, osteonecrosis
What is the classification of arsenic trioxide?
Give this one a try later!
Miscellaneous
What is Hydroxyurea classified as?
Give this one a try later!
, Miscellaneous, cell-cycle-specific (S)
What are the major side effects of Mitoxantrone?
Give this one a try later!
Stomatitis/mucositis
Myelosuppression, immunosuppression
Green-blue discoloration of sclera, urine, and skin**
Elevated liver function tests
Cardiotoxicity, CHF, cardiac arrhythmias**
Phlebitis, severe tissue damage with extravasation**
What are the major side effects of Dacarbazine?
Give this one a try later!
Nausea, vomiting, anorexia
Flu-like symptoms (fever, malaise, body aches)
Liver dysfunction
Hypersensitivity reaction
Photosensitivity
how do alkylating and alkylating-like agents work?
Give this one a try later!
, They cause DNA strand breakage or uncoiling and interfere with DNA
replication, transcriptio; DNA strands unable to separate and uncoil and
divide
What are two exampels of Epipodophyllotoxins?
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-Etoposide
-Teniposide
What are the nursing implications for Fluorouracil (5-FU)?
Give this one a try later!
Administer oral doses on an empty stomach (1 hour pre-/2 hours post
meals); avoid acidic fruit juice
Monitor stool output
Monitor cardiac symptoms
Consider using cryotherapy to help reduce stomatitis/mucositis
What are the major side effects of Mitotane?
Give this one a try later!
