unstable angine, NSTEMI
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due to thrombus , vasoconstriction of coronary artery, increased
myocardial o2 demant, intraluminal narrowing.
plaque ruptures00>monocytes circulate and turn into macrophages, ingest
LDLs, become lipid filled (foam cells), die, create lipid pool with fibrous cap
that is easily ruptured.
CRP is needed-->inflammation is trigger for plaque rupture so high CRP
means higher CV risk for MI.
microvascular angina
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, women more affected than men. chest discomfort with exercise + positive
stress test but no obstruction of coronary arteries (seen with angiography).
may be due to microvascular dysfunction or spasms that decrease blood
supply to coronary arteries.
Unstable angine and NSTEMI diagnostics
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EKG-->within 10 minutes of ER arrival
Labs: exclude anemia (get cbc), CMP (assess glucose, BUN, Cr, NA, K),
exclude thyroid cause (get TSH+), get Mg levels to assess need to
replenish. CRP to assess inflammatory response.
BNP or nproBNP to assess for heart failure
Echo: detects location/extent of dysfunction
stable angine presentation
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symptoms relieved by rest or nitro tablets. pain 1-3 minutes. usually diffuse
chest pain/pressure. So if there is a localized area no larger than fingertip
consider a different cause
pathophys carotid artery disease
Give this one a try later!
Give this one a try later!
due to thrombus , vasoconstriction of coronary artery, increased
myocardial o2 demant, intraluminal narrowing.
plaque ruptures00>monocytes circulate and turn into macrophages, ingest
LDLs, become lipid filled (foam cells), die, create lipid pool with fibrous cap
that is easily ruptured.
CRP is needed-->inflammation is trigger for plaque rupture so high CRP
means higher CV risk for MI.
microvascular angina
Give this one a try later!
, women more affected than men. chest discomfort with exercise + positive
stress test but no obstruction of coronary arteries (seen with angiography).
may be due to microvascular dysfunction or spasms that decrease blood
supply to coronary arteries.
Unstable angine and NSTEMI diagnostics
Give this one a try later!
EKG-->within 10 minutes of ER arrival
Labs: exclude anemia (get cbc), CMP (assess glucose, BUN, Cr, NA, K),
exclude thyroid cause (get TSH+), get Mg levels to assess need to
replenish. CRP to assess inflammatory response.
BNP or nproBNP to assess for heart failure
Echo: detects location/extent of dysfunction
stable angine presentation
Give this one a try later!
symptoms relieved by rest or nitro tablets. pain 1-3 minutes. usually diffuse
chest pain/pressure. So if there is a localized area no larger than fingertip
consider a different cause
pathophys carotid artery disease
Give this one a try later!
