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Evolve Pharmacology HESI EXAM 2026/2027 – Comprehensive LPN-to-ADN Transition Competency Assessment with Practice Questions and Rationales

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Evolve Pharmacology HESI EXAM 2026/2027 – Comprehensive LPN-to-ADN Transition Competency Assessment with Practice Questions and Rationales

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An older client who takes risperidone (Risperdal), an antipsychotic, is complaining of
constipation. Which dietary changes should the practical nurse (PN) recommend?


Give this one a try later!


A) Increase daily green vegetables and bran.
Feedback:
Constipation, a side effect of antipsychotics, is managed by encouraging the
client to drink additional water and increase dietary roughage, such as bran
and green vegetables daily (A). (B, C, and D) are not routine recommendations
for constipation.




The practical nurse asks a male client who came to the clinic with an upper respiratory
infection if he has any drug allergies. The client cannot remember if he does or if he ever
received penicillin. After administering the injection of penicillin, the PN tells the client to

,stay for 30 minutes of observation. Which finding should the PN identify that is indicative
of a reaction to the medication?


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A) Rash, itching, and hives.
Feedback:
A client who is unsure about the response to a new antibiotic, especially
penicillin, should be assessed for allergy to the drug after receiving a
parenteral dose. The symptoms that indicate an allergic reaction include rash,
itching, hives (A) and anaphylactic reactions causing laryngeal edema with
difficulty breathing. (B, C, and D) are not typical of allergic responses to
penicillin.




The healthcare provider prescribes cycloplegic and mydriatic ophthalmic drops for a
client who is having a cataract removal. What explanation about the drug actions should
the practical nurse (PN) provide the client?


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D) Dilates the pupil.
Feedback:
Cycloplegic drugs cause ciliary paralysis, and mydriatics dilate the pupil (D),
which facilitates access into the anterior chamber for removal of the lens in
cataract surgery. (A, B, and C) are incorrect actions.




What laboratory results should the practical nurse monitor to evaluate the therapeutic
effects of heparin?


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, D) Activated partial thromboplastin time (APTT).
Feedback:
Ongoing APTT (D) values measure the prolongation times of thromboplastin in
the clotting cascade, which is monitored during heparin therapy. (A, B, and C)
do not indicate the therapeutic action of heparin.




Which instruction should the practical nurse (PN) reinforce with a client who is taking
disulfiram (Antabuse)?


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B) Avoid using any over-the-counter substances containing alcohol.
Feedback:
The use of disulfiram (Antabuse) with over-the-counter (OTC) products that
contain alcohol causes severe adverse reactions, such as severe nausea,
vomiting, chest pain, hyperventilation, tachycardia, seizures, and
cardiovascular collapse, and should be avoided (B). Although a smoking
cessation program is always a good health recommendation (A), it is not a
priority with Antabuse. (C) is inaccurate. Small amounts, as little as 7 ml, of
mouthwash or cough syrup that contains alcohol can precipitate a disulfiram
reaction and should not be used (D).




An adult male arrives in the clinic requesting a prescription for sildenafil (Viagra). Which
client history should the practical nurse (PN) report to the healthcare provider?
A) Hypogonadism.
B) Fluid retention.
C) The use of nitrates.
D) Benign prostatic hypertrophy.


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, C) The use of nitrates.
Feedback:
Sildenafil can lower blood pressure by causing vasodilation. A client who takes
a nitrate (C), a vasodilator, for a pre-existing cardiovascular disease can
experience significant hypotension if Viagra is taken concomittently with
nitrates, such as nitroglycerin, which should be reported to the healthcare
provider. (A, B, and D) are not contraindications for the use of Viagra.




A client receives a prescription for nystatin (Mycostatin) oral suspension for the treatment
of oral thrush. Which information should the practical nurse (PN) provide?
A) Take on an empty stomach.
B) Mix the suspension with water.
C) Swish then swallow the medication.
D) Keep in the refrigerator.


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C) Swish then swallow the medication.
Feedback:
The client should swish the suspension in the mouth for as long as possible
before swallowing it (C). The method of swish and swallow distributes the
medication within the oral cavity to ensure topical coverage of the affected
mucosal surfaces. Although (A, B, and D) are medication administration
instructions, swish and swallow is the most specific administration information
for nystatin.




A client who is comatose is admitted after an overdose of baclofen (Lioresal). What
nursing action should the practical nurse (PN) implement?
A) Provide continuous telemetry monitoring.
B) Monitor for signs of respiratory arrest.

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